Matches in SemOpenAlex for { <https://semopenalex.org/work/W3010921287> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W3010921287 endingPage "S273" @default.
- W3010921287 startingPage "S272" @default.
- W3010921287 abstract "Hypertension is a common manifestation during systemic lupus erythematosus (SLE). Its mechanism is multifactorial and microthromboses of renal arterioles seem to be the most important mechanism. The objective of our study is to identify the histological and evolutionary characteristics of patients with lupus nephritis (LN) presenting with hypertension. A retrospective study of 85 patients followed for LES with lupus nephritis documented by a renal biopsy collected between 1998 and 2015 and presenting with hypertension. Among 174 patients with LN, eighty-five (48.58%) are hypertensive. A sex ratio F / H of 6.08. The mean age of LN diagnosis was 36.4 years old [13 -75 years old]. The average time to onset of hypertension was 25.8 months [0-204 months]. Malignant hypertension was present in 12% of patients. Antiphospholipid Antibody Syndrome (APLS) was found in 35.3% of cases. Renal biopsy showed LN class II in 2 cases, class III in 8 cases, class IV in 43 cases, class V isolated in 8 cases and class VI in 3 cases. Vascular lesions were arteriolosclerosis in 40% of cases and thrombotic microangiopathy (TMA) lesions in 17.6% of cases. The treatment was essentially based on blockers of the renin angiotensin system, either as monotherapy or in combination with calcium channel blockers, beta blockers or central antihypertensives. The evolution was marked by the occurrence of cerebrovascular accidents associated in 7 cases with APLS and coronary artery disease in 2 cases. Renal evolution was marked by total and durable remission in 27.5%, chronic renal disease in 31.7%, and end-stage renal failure in 40.8% of cases. Blood pressure was balanced in 40,5 % of cases and unbalanced in 59,5% of cases. In our lupus patients, hypertension was common, associated with severe glomerular and vascular lesions and a rather severe renal prognosis." @default.
- W3010921287 created "2020-03-23" @default.
- W3010921287 creator A5009185889 @default.
- W3010921287 creator A5012247314 @default.
- W3010921287 creator A5027998173 @default.
- W3010921287 creator A5054822603 @default.
- W3010921287 creator A5057706616 @default.
- W3010921287 creator A5076242950 @default.
- W3010921287 creator A5078004989 @default.
- W3010921287 creator A5085563014 @default.
- W3010921287 creator A5085970007 @default.
- W3010921287 creator A5087739388 @default.
- W3010921287 date "2020-03-01" @default.
- W3010921287 modified "2023-09-25" @default.
- W3010921287 title "SUN-177 HYPERTENSION AND RENAL DISEASE IN SYSTEMIC LUPUS ERYTHEMATOSUS" @default.
- W3010921287 doi "https://doi.org/10.1016/j.ekir.2020.02.709" @default.
- W3010921287 hasPublicationYear "2020" @default.
- W3010921287 type Work @default.
- W3010921287 sameAs 3010921287 @default.
- W3010921287 citedByCount "0" @default.
- W3010921287 crossrefType "journal-article" @default.
- W3010921287 hasAuthorship W3010921287A5009185889 @default.
- W3010921287 hasAuthorship W3010921287A5012247314 @default.
- W3010921287 hasAuthorship W3010921287A5027998173 @default.
- W3010921287 hasAuthorship W3010921287A5054822603 @default.
- W3010921287 hasAuthorship W3010921287A5057706616 @default.
- W3010921287 hasAuthorship W3010921287A5076242950 @default.
- W3010921287 hasAuthorship W3010921287A5078004989 @default.
- W3010921287 hasAuthorship W3010921287A5085563014 @default.
- W3010921287 hasAuthorship W3010921287A5085970007 @default.
- W3010921287 hasAuthorship W3010921287A5087739388 @default.
- W3010921287 hasBestOaLocation W30109212871 @default.
- W3010921287 hasConcept C126322002 @default.
- W3010921287 hasConcept C2775934546 @default.
- W3010921287 hasConcept C2776912625 @default.
- W3010921287 hasConcept C2777878052 @default.
- W3010921287 hasConcept C2779134260 @default.
- W3010921287 hasConcept C2779912601 @default.
- W3010921287 hasConcept C2780793064 @default.
- W3010921287 hasConcept C2781087799 @default.
- W3010921287 hasConcept C71924100 @default.
- W3010921287 hasConcept C90924648 @default.
- W3010921287 hasConceptScore W3010921287C126322002 @default.
- W3010921287 hasConceptScore W3010921287C2775934546 @default.
- W3010921287 hasConceptScore W3010921287C2776912625 @default.
- W3010921287 hasConceptScore W3010921287C2777878052 @default.
- W3010921287 hasConceptScore W3010921287C2779134260 @default.
- W3010921287 hasConceptScore W3010921287C2779912601 @default.
- W3010921287 hasConceptScore W3010921287C2780793064 @default.
- W3010921287 hasConceptScore W3010921287C2781087799 @default.
- W3010921287 hasConceptScore W3010921287C71924100 @default.
- W3010921287 hasConceptScore W3010921287C90924648 @default.
- W3010921287 hasIssue "3" @default.
- W3010921287 hasLocation W30109212871 @default.
- W3010921287 hasOpenAccess W3010921287 @default.
- W3010921287 hasPrimaryLocation W30109212871 @default.
- W3010921287 hasRelatedWork W1770337685 @default.
- W3010921287 hasRelatedWork W2117328268 @default.
- W3010921287 hasRelatedWork W2120180438 @default.
- W3010921287 hasRelatedWork W2414615690 @default.
- W3010921287 hasRelatedWork W2467350723 @default.
- W3010921287 hasRelatedWork W3106988363 @default.
- W3010921287 hasRelatedWork W3133971152 @default.
- W3010921287 hasRelatedWork W3164471077 @default.
- W3010921287 hasRelatedWork W4285613386 @default.
- W3010921287 hasRelatedWork W45214655 @default.
- W3010921287 hasVolume "5" @default.
- W3010921287 isParatext "false" @default.
- W3010921287 isRetracted "false" @default.
- W3010921287 magId "3010921287" @default.
- W3010921287 workType "article" @default.