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- W3010977327 endingPage "907" @default.
- W3010977327 startingPage "895" @default.
- W3010977327 abstract "Objective: Endometriosis affects up to 10% of women of reproductive age, and the main goal of treatment is to relieve symptoms. Progestins have been the mainstay of endometriosis suppression, of which dienogest has become an important option in many parts of the world. This is an expert literature review, with recommendations on the use of dienogest in the context of various clinical considerations when treating endometriosis.Methods: A search of PubMed was conducted for papers published between 2007 and 2019 on the use of dienogest in endometriosis. Experts reviewed these and included those they considered most relevant in clinical practice, according to their own clinical experience.Results: Evidence regarding the long-term use (>15 months) of dienogest for the management of endometriosis is presented, with experts concluding that the efficacy of dienogest should be assessed primarily on its impact on pain and quality of life. Fertility preservation, the option to avoid or delay surgery, and managing bleeding irregularities that can occur with this treatment are also considered. Counseling women on potential bleeding risks before starting treatment may be helpful, and evidence suggests that few women discontinue treatment for this reason, with the benefits of treatment outweighing any impact of bleeding irregularities.Conclusions: Overall, the evidence demonstrates that dienogest offers an effective and tolerable alternative or adjunct to surgery and provides many advantages over combined hormonal contraceptives for the treatment of endometriosis. It is important that treatment guidelines are followed and care is tailored to the woman's individual needs and desires." @default.
- W3010977327 created "2020-03-23" @default.
- W3010977327 creator A5009111607 @default.
- W3010977327 creator A5018591454 @default.
- W3010977327 creator A5020919310 @default.
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- W3010977327 creator A5066195595 @default.
- W3010977327 creator A5067153931 @default.
- W3010977327 creator A5081966221 @default.
- W3010977327 date "2020-03-31" @default.
- W3010977327 modified "2023-10-18" @default.
- W3010977327 title "Use of dienogest in endometriosis: a narrative literature review and expert commentary" @default.
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