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• W3011008058 abstract "Abstract Background To explore the effects of the respiratory rate (RR) on the venous-to-arterial CO 2 tension difference (gapCO 2 ) in septic shock patients undergoing volume mechanical ventilation. Methods Adult patients with septic shock underwent volume mechanical ventilation between October 2015 and October 2016. RR was started at 10 breaths/min, and 2 breaths/min were added every 60 min until 16 breaths/min was reached. At every point, central venous and arterial blood gas measurements were obtained simultaneously. Results In this study, gapCO 2 induced by hyperventilation significantly increased, while the central venous carbon dioxide pressure (PvCO 2 ) and the partial pressure of CO 2 (PaCO 2 ) in arteries decreased. The decreasing trend of the PaCO 2 was more obvious than that of the PvCO 2 . HCO 3 − and ctCO 2 were markedly decreased, when the RR was increased ( P < 0.05). Central venous oxygen saturation (S cv O 2 ) had a decreasing trend between 14 (77.1 ± 8.3%) and 16 (75.2 ± 8.7%) breaths/min; however, the difference was not significant. Conclusions In septic patients undergoing ventilation, respiratory alkalosis induced by hyperventilation caused an increase in the gapCO 2 . Clinicians should cautiously interpret the gapCO 2 in hemodynamically stable ventilated septic shock patients and its relationship with low cardiac output and inadequate perfusion." @default.
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• W3011008058 date "2020-03-17" @default.
• W3011008058 modified "2023-09-26" @default.
• W3011008058 title "Effects of respiratory rate on venous-to-arterial CO2 tension difference in septic shock patients undergoing volume mechanical ventilation" @default.
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• W3011008058 doi "https://doi.org/10.1186/s40001-020-00402-9" @default.
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