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- W3011010256 abstract "In this study, the crude polysaccharide (HMP) was extracted from Hypsizygus marmoreus using water-extraction and alcohol-precipitation methods. The separation and purification were performed followed by the preparation of the homogeneous polysaccharide termed as HMP-1. The structural feature of HMP-1 was investigated by a combination of chemical and instrumental analyses. The results showed that the average molecular weight of HMP-1 was 1.92 × 103 kDa. Besides, monosaccharide composition analysis showed that the HMP-1 mainly consist of d-mannose, d-glucose and d-galactose in the molar ratio of 1.145:5.282:1.157. The periodate oxidation, smith degradation and methylation results revealed that the main chain of HMP-1 was composed by →4)-D-Glcp-(1→, →6)-D-Galp-(1→, →4,6)-D-Glcp-(1→ and D-Glcp-(1→, while the side chain was →3)-D-Manp-(1→, D-Manp-(1→ and D-Glcp-(1 → . α-Glucosidase inhibitory activity experiment result showed that HMP-1 was able to inhibit the activity of α-glucosidase. Therefore, as the chemical structure and biological activity of HMP-1 were clearly characterized, Hypsizygus marmoreus can be used as a reference source for drug preparations." @default.
- W3011010256 created "2020-03-23" @default.
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- W3011010256 date "2020-07-01" @default.
- W3011010256 modified "2023-10-16" @default.
- W3011010256 title "Chemical structure and inhibition on α-glucosidase of a novel polysaccharide from Hypsizygus marmoreus" @default.
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- W3011010256 doi "https://doi.org/10.1016/j.molstruc.2020.128110" @default.
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