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• W3011063004 abstract "In recent decades, there has been an increase in the prevalence of allergic diseases around the world. In industrialized countries, the prevalence of allergic rhinitis reaches up to 40%. Symptoms of allergic rhinitis can have a negative impact on patients’ quality of life, disturb sleep, and contribute to poor school performance. In allergic rhinitis, characteristic changes of the nasal mucous membrane epithelium are noted: metaplasia of goblet cells; exfoliation of the epithelium; decrease in number of cells with mobile cilia; loss of cilia by epithelial cells; infiltration of mucous membrane by inflammatory cells; thickening of basal membrane. Symptoms of allergic rhinitis include rhinorrhoea, obstructed nasal breathing, itching and sneezing. Modern classifications of allergic rhinitis take into account the etiology, duration and severity of symptoms and pathophysiological changes. Allergic rhinitis often debut in children under 6, which is often preceded by sensitization. The algorithm of management of patients with allergic rhinitis has four main methods that are necessary simultaneously: training of patients, including children and their parents, elimination of allergens, pharmacotherapy, immunotherapy. Elimination measures are very important for patients with allergic rhinitis, but it is not always possible to completely eliminate contact with the causal allergen. The choice of drug therapy depends on the form and clinical severity of the disease, the age of the patient (age restriction of the drug), the availability of the drug in pharmacies and its price, as well as the acceptability and satisfaction of the patient with the specific treatment method. Intranasal antihistamines have been shown to be highly effective in reducing symptoms such as sneezing, rhinorrhoea, itching, and to a lesser extent - nasal congestion. Intranasal antihistamines also have faster onset than oral antihistamines. Nasal congestion is most effectively facilitated by decongestants." @default.
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• W3011063004 date "2020-03-09" @default.
• W3011063004 modified "2023-09-27" @default.
• W3011063004 title "Allergic rhinitis in children: a modern view of therapy" @default.
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• W3011063004 doi "https://doi.org/10.21518/2079-701x-2020-1-130-133" @default.
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