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- W3011112054 abstract "In this research,typical organic/inorganic photothermal therapy(PTT) agents were designed with a combination of upconversion luminescent(UCL) or near-infrared (NIR) II imaging rare-earth nanomaterials forphoto-acoustic (PA)/UCL/NIR II imaging-guided PTT under NIR laserirradiation. The results show the following: (1) The PTT effect mainlycomes from NIR absorption and partly from UCL light conversion. (2)Visible UCL emission is mainly quenched by NIR absorption of the coatedPTT agent and partly quenched by visible absorption, indicating thatexcitation may play a more important role than in the UCL emissionprocess. (3) The biostability of the composite might be decided bythe synthesis reaction temperature. Among the five inorganic/organicnanocomposites, UCNP@MnO2 is the most suitable candidatefor cancer diagnosis and treatment because of its stimuli-responseability to the micro-acid environment of tumor cells and highest biostability.The composites generate heat for PTT after entering the tumor cells,and then, the visible light emission gradually regains as MnO2 is reduced to colorless Mn2+ ions, thereby illuminatingthe cancer cells after the therapy." @default.
- W3011112054 created "2020-03-23" @default.
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- W3011112054 date "2020-03-19" @default.
- W3011112054 modified "2023-10-13" @default.
- W3011112054 title "Lanthanide-Based Nanocomposites for Photothermal Therapy under Near-Infrared Laser: Relationship between Light and Heat, Biostability, and Reaction Temperature" @default.
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- W3011112054 doi "https://doi.org/10.1021/acs.langmuir.0c00343" @default.
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