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- W3011315185 abstract "Neural stem cells (NSCs) have gained significant scientific and commercial interest in the last 15 years. Given their plasticity, defined as the ability to develop into different phenotypes inside and outside of the nervous system, with capacity of almost unlimited self-renewal, of releasing trophic and immunomodulatory factors and of exploiting temporal and spatial dynamics, NSCs have been proposed for i) neurotoxicity testing; ii) cellular therapies to treat CNS diseases; iii) neural tissue engineering and repair; iv) drug target validation and testing; v) personalized medicine. Moreover, given the growing interest of developing cell-based therapies to target neurodegenerative diseases, recent progresses in developing NSCs from human-induced pluripotent stem cells have licensed an analog of endogenous NSCs Herein, we will review the current understanding on emerging conceptual and technological topics in the neural stem cell field such as deep characterization of the human compartment, single cell spatial-temporal dynamics, reprogramming from somatic cells or NSC manipulation and monitoring. Altogether those aspects contribute to further disentangle NSC plasticity to better exploit the potential of those cells that in the future might offer new strategies for brain therapies." @default.
- W3011315185 created "2020-03-23" @default.
- W3011315185 creator A5003067809 @default.
- W3011315185 creator A5029732475 @default.
- W3011315185 creator A5060623848 @default.
- W3011315185 date "2020-03-20" @default.
- W3011315185 modified "2023-10-10" @default.
- W3011315185 title "Therapeutic Plasticity of Neural Stem Cells" @default.
- W3011315185 cites W128396052 @default.
- W3011315185 cites W1513529766 @default.
- W3011315185 cites W1533389761 @default.
- W3011315185 cites W1539462532 @default.
- W3011315185 cites W1540546146 @default.
- W3011315185 cites W1563398459 @default.
- W3011315185 cites W1564898390 @default.
- W3011315185 cites W1564952613 @default.
- W3011315185 cites W1570545162 @default.
- W3011315185 cites W1571742199 @default.
- W3011315185 cites W1592283056 @default.
- W3011315185 cites W1595834812 @default.
- W3011315185 cites W1597141946 @default.
- W3011315185 cites W1606173244 @default.
- W3011315185 cites W1617074755 @default.
- W3011315185 cites W1666901150 @default.
- W3011315185 cites W1760682360 @default.
- W3011315185 cites W1774728488 @default.
- W3011315185 cites W1828558002 @default.
- W3011315185 cites W1835798525 @default.
- W3011315185 cites W1859730138 @default.
- W3011315185 cites W1861988602 @default.
- W3011315185 cites W1905790310 @default.
- W3011315185 cites W1921871464 @default.
- W3011315185 cites W1926043920 @default.
- W3011315185 cites W1933245065 @default.
- W3011315185 cites W1963724707 @default.
- W3011315185 cites W1964285345 @default.
- W3011315185 cites W1964980861 @default.
- W3011315185 cites W1965810526 @default.
- W3011315185 cites W1966100398 @default.
- W3011315185 cites W1968673355 @default.
- W3011315185 cites W1969043349 @default.
- W3011315185 cites W1969905245 @default.
- W3011315185 cites W1971044205 @default.
- W3011315185 cites W1971967959 @default.
- W3011315185 cites W1973439716 @default.
- W3011315185 cites W1978253837 @default.
- W3011315185 cites W1980499453 @default.
- W3011315185 cites W1980940171 @default.
- W3011315185 cites W1982850249 @default.
- W3011315185 cites W1985530230 @default.
- W3011315185 cites W1986219188 @default.
- W3011315185 cites W1986579256 @default.
- W3011315185 cites W1988352722 @default.
- W3011315185 cites W1988601362 @default.
- W3011315185 cites W1988896202 @default.
- W3011315185 cites W1989140838 @default.
- W3011315185 cites W1989266013 @default.
- W3011315185 cites W1990044878 @default.
- W3011315185 cites W1990564529 @default.
- W3011315185 cites W1990573718 @default.
- W3011315185 cites W1991006196 @default.
- W3011315185 cites W1991614955 @default.
- W3011315185 cites W1993353576 @default.
- W3011315185 cites W1993678030 @default.
- W3011315185 cites W1994348124 @default.
- W3011315185 cites W1994796110 @default.
- W3011315185 cites W1995827857 @default.
- W3011315185 cites W1997496613 @default.
- W3011315185 cites W1998463679 @default.
- W3011315185 cites W1999053936 @default.
- W3011315185 cites W2001392873 @default.
- W3011315185 cites W2001419937 @default.
- W3011315185 cites W2003503502 @default.
- W3011315185 cites W2004927868 @default.
- W3011315185 cites W2007543609 @default.
- W3011315185 cites W2011580597 @default.
- W3011315185 cites W2012253237 @default.
- W3011315185 cites W2014407542 @default.
- W3011315185 cites W2015636063 @default.
- W3011315185 cites W2016500868 @default.
- W3011315185 cites W2017084943 @default.
- W3011315185 cites W2017584345 @default.
- W3011315185 cites W2018286352 @default.
- W3011315185 cites W2019454133 @default.
- W3011315185 cites W2021766835 @default.
- W3011315185 cites W2023025245 @default.
- W3011315185 cites W2023168515 @default.
- W3011315185 cites W2023291891 @default.
- W3011315185 cites W2023656078 @default.
- W3011315185 cites W2026598324 @default.
- W3011315185 cites W2027449023 @default.
- W3011315185 cites W2028699052 @default.
- W3011315185 cites W2030396039 @default.
- W3011315185 cites W2031421193 @default.
- W3011315185 cites W2032925963 @default.
- W3011315185 cites W2033032660 @default.
- W3011315185 cites W2033500695 @default.
- W3011315185 cites W2038530570 @default.
- W3011315185 cites W2040118612 @default.
- W3011315185 cites W2041977230 @default.