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- W3011341467 endingPage "490" @default.
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- W3011341467 abstract "Abstract The brain’s relationship to essential hypertension is primarily understood to be that of an end-organ, damaged late in life by stroke or dementia. Emerging evidence, however, shows that heightened blood pressure (BP) early in life and prior to traditionally defined hypertension, relates to altered brain structure, cerebrovascular function, and cognitive processing. Deficits in cognitive function, cerebral blood flow responsivity, volumes of brain areas, and white matter integrity all relate to increased but prehypertensive levels of BP. Such relationships may be observed as early as childhood. In this review, we consider the basis of these relationships by examining the emergence of putative causative factors for hypertension that would impact or involve brain function/structure, e.g., sympathetic nervous system activation and related endocrine and inflammatory activation. Currently, however, available evidence is not sufficient to fully explain the specific pattern of brain deficits related to heightened BP. Despite this uncertainty, the evidence reviewed suggests the value that early intervention may have, not only for reducing BP, but also for maintaining brain function." @default.
- W3011341467 created "2020-03-23" @default.
- W3011341467 creator A5000985873 @default.
- W3011341467 creator A5025219266 @default.
- W3011341467 creator A5039585998 @default.
- W3011341467 date "2020-03-14" @default.
- W3011341467 modified "2023-09-23" @default.
- W3011341467 title "Is the Brain an Early or Late Component of Essential Hypertension?" @default.
- W3011341467 cites W153408323 @default.
- W3011341467 cites W1601613757 @default.
- W3011341467 cites W1653011747 @default.
- W3011341467 cites W1840594301 @default.
- W3011341467 cites W1973807084 @default.
- W3011341467 cites W1979370053 @default.
- W3011341467 cites W1980201732 @default.
- W3011341467 cites W1980683585 @default.
- W3011341467 cites W1983715761 @default.
- W3011341467 cites W1987880972 @default.
- W3011341467 cites W1988082450 @default.
- W3011341467 cites W1988388756 @default.
- W3011341467 cites W1997763915 @default.
- W3011341467 cites W1998817898 @default.
- W3011341467 cites W1999241129 @default.
- W3011341467 cites W2000085854 @default.
- W3011341467 cites W2013480805 @default.
- W3011341467 cites W2023126015 @default.
- W3011341467 cites W2030992436 @default.
- W3011341467 cites W2035363453 @default.
- W3011341467 cites W2043661019 @default.
- W3011341467 cites W2044416817 @default.
- W3011341467 cites W2045031822 @default.
- W3011341467 cites W2051259967 @default.
- W3011341467 cites W2054523815 @default.
- W3011341467 cites W2059095381 @default.
- W3011341467 cites W2065249546 @default.
- W3011341467 cites W2069152309 @default.
- W3011341467 cites W2073394329 @default.
- W3011341467 cites W2074560470 @default.
- W3011341467 cites W2076699009 @default.
- W3011341467 cites W2081457754 @default.
- W3011341467 cites W2088175856 @default.
- W3011341467 cites W2088230441 @default.
- W3011341467 cites W2088427061 @default.
- W3011341467 cites W2090240743 @default.
- W3011341467 cites W2093140436 @default.
- W3011341467 cites W2097602322 @default.
- W3011341467 cites W2099962940 @default.
- W3011341467 cites W2102264398 @default.
- W3011341467 cites W2104177477 @default.
- W3011341467 cites W2118411978 @default.
- W3011341467 cites W2118648850 @default.
- W3011341467 cites W2121642559 @default.
- W3011341467 cites W2124407174 @default.
- W3011341467 cites W2130577608 @default.
- W3011341467 cites W2130766313 @default.
- W3011341467 cites W2131532508 @default.
- W3011341467 cites W2135634877 @default.
- W3011341467 cites W2146667985 @default.
- W3011341467 cites W2156971293 @default.
- W3011341467 cites W2163107621 @default.
- W3011341467 cites W2163613769 @default.
- W3011341467 cites W2166731508 @default.
- W3011341467 cites W2166791505 @default.
- W3011341467 cites W2171078840 @default.
- W3011341467 cites W2171519439 @default.
- W3011341467 cites W2322678100 @default.
- W3011341467 cites W2327663417 @default.
- W3011341467 cites W2327807354 @default.
- W3011341467 cites W2328407444 @default.
- W3011341467 cites W2336711000 @default.
- W3011341467 cites W2343296574 @default.
- W3011341467 cites W2368388378 @default.
- W3011341467 cites W2418338139 @default.
- W3011341467 cites W2525975480 @default.
- W3011341467 cites W2526284382 @default.
- W3011341467 cites W2527609605 @default.
- W3011341467 cites W2529464446 @default.
- W3011341467 cites W2530115453 @default.
- W3011341467 cites W2536317907 @default.
- W3011341467 cites W2545669894 @default.
- W3011341467 cites W2557880103 @default.
- W3011341467 cites W2562525710 @default.
- W3011341467 cites W2576595026 @default.
- W3011341467 cites W2594345737 @default.
- W3011341467 cites W2603112182 @default.
- W3011341467 cites W2610469200 @default.
- W3011341467 cites W2617934305 @default.
- W3011341467 cites W2621215132 @default.
- W3011341467 cites W2731491363 @default.
- W3011341467 cites W2738822837 @default.
- W3011341467 cites W2761061704 @default.
- W3011341467 cites W2766765514 @default.
- W3011341467 cites W2767355593 @default.
- W3011341467 cites W2783468975 @default.
- W3011341467 cites W2897064514 @default.
- W3011341467 cites W2900649959 @default.
- W3011341467 cites W2915850409 @default.
- W3011341467 cites W2945507856 @default.