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• W3011370864 abstract "Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths in the United States. Furthermore, it is well established that obese individuals have high risks of developing CRC, and obesity-associated CRC represents an unmet medical problem in the United States. Using a metabolomics approach, our recent research supports that the cytochrome P450 (CYP) monooxygenase/soluble epoxide hydrolase (sEH)-mediated eicosanoid pathway could play critical roles in the pathogenesis of CRC and obesity-associated CRC. Here in this review, we discuss recent studies about the roles of the CYP/sEH eicosanoid pathway in the pathogenesis of these diseases." @default.
• W3011370864 created "2020-03-23" @default.
• W3011370864 creator A5044229632 @default.
• W3011370864 creator A5089378951 @default.
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• W3011370864 date "2019-08-23" @default.
• W3011370864 modified "2023-09-25" @default.
• W3011370864 title "Cytochrome P450 monooxygenase/soluble epoxide hydrolase-mediated eicosanoid pathway in colorectal cancer and obesity-associated colorectal cancer" @default.
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• W3011370864 doi "https://doi.org/10.18632/oncoscience.488" @default.
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