Matches in SemOpenAlex for { <https://semopenalex.org/work/W3011431481> ?p ?o ?g. }
- W3011431481 abstract "Abstract The responses of cells to their surroundings are mediated by the binding of cell surface proteins (CSPs) to extracellular signals. Such processes are regulated via dynamic changes in the structure, composition, and expression levels of CSPs. In this study, we demonstrate the possibility of decorating bacteria with artificial, self-assembled receptors that imitate the dynamic features of CSPs. We show that the local concentration of these receptors on the bacterial membrane and their structure can be reversibly controlled using suitable chemical signals, in a way that resembles changes that occur with CSP expression levels or posttranslational modifications (PTMs), respectively. We also show that these modifications can endow the bacteria with programmable properties, akin to the way CSP responses can induce cellular functions. By programming the bacteria to glow, adhere to surfaces, or interact with proteins or mammalian cells, we demonstrate the potential to tailor such biomimetic systems for specific applications." @default.
- W3011431481 created "2020-03-23" @default.
- W3011431481 creator A5000101285 @default.
- W3011431481 creator A5033654232 @default.
- W3011431481 creator A5041261143 @default.
- W3011431481 creator A5048585838 @default.
- W3011431481 creator A5049994035 @default.
- W3011431481 creator A5061704187 @default.
- W3011431481 creator A5068016555 @default.
- W3011431481 creator A5076914026 @default.
- W3011431481 creator A5083469891 @default.
- W3011431481 date "2020-03-10" @default.
- W3011431481 modified "2023-10-10" @default.
- W3011431481 title "Decorating bacteria with self-assembled synthetic receptors" @default.
- W3011431481 cites W1921492782 @default.
- W3011431481 cites W1972673148 @default.
- W3011431481 cites W1974119662 @default.
- W3011431481 cites W1976791804 @default.
- W3011431481 cites W1977125051 @default.
- W3011431481 cites W1977878598 @default.
- W3011431481 cites W1978513278 @default.
- W3011431481 cites W1979108979 @default.
- W3011431481 cites W1981659539 @default.
- W3011431481 cites W1984537439 @default.
- W3011431481 cites W2000606502 @default.
- W3011431481 cites W2002192998 @default.
- W3011431481 cites W2006579803 @default.
- W3011431481 cites W2013980015 @default.
- W3011431481 cites W2028355094 @default.
- W3011431481 cites W2028415754 @default.
- W3011431481 cites W2031858174 @default.
- W3011431481 cites W2039589883 @default.
- W3011431481 cites W2039684640 @default.
- W3011431481 cites W2041806467 @default.
- W3011431481 cites W2052052881 @default.
- W3011431481 cites W2057788156 @default.
- W3011431481 cites W2070102480 @default.
- W3011431481 cites W2071033460 @default.
- W3011431481 cites W2075460623 @default.
- W3011431481 cites W2090651532 @default.
- W3011431481 cites W2107167859 @default.
- W3011431481 cites W2111520742 @default.
- W3011431481 cites W2113138384 @default.
- W3011431481 cites W211729685 @default.
- W3011431481 cites W2127347791 @default.
- W3011431481 cites W2128121220 @default.
- W3011431481 cites W2135349490 @default.
- W3011431481 cites W2146394719 @default.
- W3011431481 cites W2154367235 @default.
- W3011431481 cites W2154980023 @default.
- W3011431481 cites W2158821132 @default.
- W3011431481 cites W2167192225 @default.
- W3011431481 cites W2167723084 @default.
- W3011431481 cites W2178610589 @default.
- W3011431481 cites W2189360969 @default.
- W3011431481 cites W2216044891 @default.
- W3011431481 cites W2283768968 @default.
- W3011431481 cites W2323436860 @default.
- W3011431481 cites W2324690081 @default.
- W3011431481 cites W2327086333 @default.
- W3011431481 cites W2332024781 @default.
- W3011431481 cites W2408589030 @default.
- W3011431481 cites W2560345632 @default.
- W3011431481 cites W2588424256 @default.
- W3011431481 cites W2604646706 @default.
- W3011431481 cites W2607287108 @default.
- W3011431481 cites W2614052840 @default.
- W3011431481 cites W2614400304 @default.
- W3011431481 cites W2619969316 @default.
- W3011431481 cites W2753240448 @default.
- W3011431481 cites W2765741363 @default.
- W3011431481 cites W2782859760 @default.
- W3011431481 cites W2783181233 @default.
- W3011431481 cites W2786946130 @default.
- W3011431481 cites W2791476158 @default.
- W3011431481 cites W2803175246 @default.
- W3011431481 cites W2806148921 @default.
- W3011431481 cites W2883593500 @default.
- W3011431481 cites W2897207821 @default.
- W3011431481 cites W2898873576 @default.
- W3011431481 cites W2901245659 @default.
- W3011431481 cites W2905205401 @default.
- W3011431481 cites W2906406229 @default.
- W3011431481 cites W2914839653 @default.
- W3011431481 cites W4241634501 @default.
- W3011431481 cites W4243789264 @default.
- W3011431481 doi "https://doi.org/10.1038/s41467-020-14336-7" @default.
- W3011431481 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7064574" @default.
- W3011431481 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32157077" @default.
- W3011431481 hasPublicationYear "2020" @default.
- W3011431481 type Work @default.
- W3011431481 sameAs 3011431481 @default.
- W3011431481 citedByCount "29" @default.
- W3011431481 countsByYear W30114314812020 @default.
- W3011431481 countsByYear W30114314812021 @default.
- W3011431481 countsByYear W30114314812022 @default.
- W3011431481 countsByYear W30114314812023 @default.
- W3011431481 crossrefType "journal-article" @default.
- W3011431481 hasAuthorship W3011431481A5000101285 @default.
- W3011431481 hasAuthorship W3011431481A5033654232 @default.