FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3011543640> ?p ?o ?g. }

• W3011543640 endingPage "2071" @default.
• W3011543640 startingPage "2062" @default.
• W3011543640 abstract "Hydrogen sulfide (H2S) is an endogenous gasotransmitter in the human body involved in various physiological functions including cytoprotection, maintaining homeostasis, and regulation of organ development. Therefore, H2S-releasing polymers that can imitate endogenous H2S release can offer great therapeutic potential. Despite decades of research, the use of H2S donors in medical device applications is mostly unexplored largely due to the challenge of the steady H2S release from a suitable polymeric platform that does not compromise the normal cellular functions of the host. In this work, an exogenous H2S release system was developed by integrating sodium sulfide (Na2S), a common H2S donor, into a medical-grade thermoplastic silicone-polycarbonate-urethane polymer, Carbosil 20 80A (hereon as Carbosil), via a facile solvent evaporation technique. The spatial distribution and nature of Na2S in Carbosil were characterized through X-ray diffraction (XRD) spectroscopy and field emission scanning electron microscopy (FESEM) with energy-dispersive spectroscopy (EDS), indicating an amorphous phase shift upon incorporating Na2S in Carbosil. The composite, Na2S-Carbosil, is responsive in physiological conditions, resulting in sustained H2S release measured for 3 h. In vitro cellular responses of 3T3 mouse fibroblasts, human lung epithelial (HLE), and primary human umbilical vein endothelial cells (HUVEC) were investigated. Fibroblast cells showed cell proliferation in 24 h and complete cell migration in 42 h in vitro. The Na2S-Carbosil composites were cytocompatible toward HUVEC and HLE cells. This study provided important in vitro proof of concept that warrants potential use of these H2S-releasing platforms in engineering biomedical devices, tissue engineering, and drug delivery applications." @default.
• W3011543640 created "2020-03-23" @default.
• W3011543640 creator A5024724191 @default.
• W3011543640 creator A5033641096 @default.
• W3011543640 creator A5040592734 @default.
• W3011543640 creator A5041447331 @default.
• W3011543640 creator A5045333775 @default.
• W3011543640 creator A5059877583 @default.
• W3011543640 date "2020-03-13" @default.
• W3011543640 modified "2023-09-26" @default.
• W3011543640 title "H₂S-Releasing Composite: a Gasotransmitter Platform for Potential Biomedical Applications" @default.
• W3011543640 cites W1412109522 @default.
• W3011543640 cites W1497515855 @default.
• W3011543640 cites W1972355061 @default.
• W3011543640 cites W1977830159 @default.
• W3011543640 cites W1986221786 @default.
• W3011543640 cites W1988937935 @default.
• W3011543640 cites W1990839876 @default.
• W3011543640 cites W1992450168 @default.
• W3011543640 cites W1997751338 @default.
• W3011543640 cites W1999838214 @default.
• W3011543640 cites W2002408287 @default.
• W3011543640 cites W2005980540 @default.
• W3011543640 cites W2007936423 @default.
• W3011543640 cites W2008863925 @default.
• W3011543640 cites W2009585923 @default.
• W3011543640 cites W2010201046 @default.
• W3011543640 cites W2013491094 @default.
• W3011543640 cites W2013741750 @default.
• W3011543640 cites W2014515422 @default.
• W3011543640 cites W2015991271 @default.
• W3011543640 cites W2019922483 @default.
• W3011543640 cites W2021215174 @default.
• W3011543640 cites W2022696269 @default.
• W3011543640 cites W2027514447 @default.
• W3011543640 cites W2028637052 @default.
• W3011543640 cites W2029377122 @default.
• W3011543640 cites W2035889676 @default.
• W3011543640 cites W2044242789 @default.
• W3011543640 cites W2045910150 @default.
• W3011543640 cites W2050742799 @default.
• W3011543640 cites W2054064167 @default.
• W3011543640 cites W2054567864 @default.
• W3011543640 cites W2071146637 @default.
• W3011543640 cites W2072610511 @default.
• W3011543640 cites W2089389631 @default.
• W3011543640 cites W2100592123 @default.
• W3011543640 cites W2102013706 @default.
• W3011543640 cites W2103880422 @default.
• W3011543640 cites W2106517022 @default.
• W3011543640 cites W2111316958 @default.
• W3011543640 cites W2133840693 @default.
• W3011543640 cites W2144026946 @default.
• W3011543640 cites W2161146123 @default.
• W3011543640 cites W2165000537 @default.
• W3011543640 cites W2165892241 @default.
• W3011543640 cites W2169413646 @default.
• W3011543640 cites W2177144915 @default.
• W3011543640 cites W2226662974 @default.
• W3011543640 cites W2254265185 @default.
• W3011543640 cites W2292312621 @default.
• W3011543640 cites W2515956294 @default.
• W3011543640 cites W2529341556 @default.
• W3011543640 cites W2575770495 @default.
• W3011543640 cites W2595415744 @default.
• W3011543640 cites W2605840825 @default.
• W3011543640 cites W2607308150 @default.
• W3011543640 cites W2620692413 @default.
• W3011543640 cites W2623511697 @default.
• W3011543640 cites W2726833281 @default.
• W3011543640 cites W2741189883 @default.
• W3011543640 cites W2756864383 @default.
• W3011543640 cites W2767914703 @default.
• W3011543640 cites W2779890638 @default.
• W3011543640 cites W2915542748 @default.
• W3011543640 cites W2954062875 @default.
• W3011543640 cites W6579719 @default.
• W3011543640 cites W2286725433 @default.
• W3011543640 doi "https://doi.org/10.1021/acsbiomaterials.0c00146" @default.
• W3011543640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33455343" @default.
• W3011543640 hasPublicationYear "2020" @default.
• W3011543640 type Work @default.
• W3011543640 sameAs 3011543640 @default.
• W3011543640 citedByCount "7" @default.
• W3011543640 countsByYear W30115436402021 @default.
• W3011543640 countsByYear W30115436402022 @default.
• W3011543640 countsByYear W30115436402023 @default.
• W3011543640 crossrefType "journal-article" @default.
• W3011543640 hasAuthorship W3011543640A5024724191 @default.
• W3011543640 hasAuthorship W3011543640A5033641096 @default.
• W3011543640 hasAuthorship W3011543640A5040592734 @default.
• W3011543640 hasAuthorship W3011543640A5041447331 @default.
• W3011543640 hasAuthorship W3011543640A5045333775 @default.
• W3011543640 hasAuthorship W3011543640A5059877583 @default.
• W3011543640 hasConcept C104779481 @default.
• W3011543640 hasConcept C127413603 @default.
• W3011543640 hasConcept C136229726 @default.
• W3011543640 hasConcept C159985019 @default.

• next