FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3011566364> ?p ?o ?g. }

• W3011566364 endingPage "1057" @default.
• W3011566364 startingPage "1050" @default.
• W3011566364 abstract "Yeast-derived β-glucan particles (GPs) are a class of microcarriers under development for the delivery of drugs and imaging agents to immune-system cells for theranostic approaches. However, the encapsulation of hydrophilic imaging agents in the porous GPs is challenging. Here, we show that the unique coordination chemistry of FeIII-based macrocyclic T1 MRI contrast agents permits facile encapsulation in GPs. Remarkably, GPs labeled with the simple FeIII complexes are stable under physiologically relevant conditions, despite the absence of amphiphilic groups. In contrast to the free FeIII coordination complex, the labeled FeIII-GPs have lowered T1 relaxivity and act as a silenced form of the contrast agent. Addition of a fluorescent tag to the FeIII complex produces a bimodal agent to further enable tracking of the nanoparticles and to monitor release. Treatment of the iron-labeled GPs with a maltol chelator or with mildly acidic conditions releases the intact iron complex and restores enhanced T1 relaxation of the water protons." @default.
• W3011566364 created "2020-03-23" @default.
• W3011566364 creator A5005873881 @default.
• W3011566364 creator A5011976803 @default.
• W3011566364 creator A5036803810 @default.
• W3011566364 creator A5050648586 @default.
• W3011566364 creator A5074529781 @default.
• W3011566364 creator A5086244003 @default.
• W3011566364 date "2020-04-14" @default.
• W3011566364 modified "2023-09-25" @default.
• W3011566364 title "Binding and Release of FeIII Complexes from Glucan Particles for the Delivery of T ₁ MRI Contrast Agents" @default.
• W3011566364 cites W1990645562 @default.
• W3011566364 cites W1998871484 @default.
• W3011566364 cites W1999732094 @default.
• W3011566364 cites W2017059861 @default.
• W3011566364 cites W2044173549 @default.
• W3011566364 cites W2054756697 @default.
• W3011566364 cites W2055981765 @default.
• W3011566364 cites W2061352374 @default.
• W3011566364 cites W2074844176 @default.
• W3011566364 cites W2076769768 @default.
• W3011566364 cites W2081514177 @default.
• W3011566364 cites W2084777656 @default.
• W3011566364 cites W2095929490 @default.
• W3011566364 cites W2097568210 @default.
• W3011566364 cites W2121995105 @default.
• W3011566364 cites W2123202621 @default.
• W3011566364 cites W2127178472 @default.
• W3011566364 cites W2137073891 @default.
• W3011566364 cites W2156128675 @default.
• W3011566364 cites W2166145829 @default.
• W3011566364 cites W2191517493 @default.
• W3011566364 cites W2300479003 @default.
• W3011566364 cites W2330080280 @default.
• W3011566364 cites W2538434739 @default.
• W3011566364 cites W2612568177 @default.
• W3011566364 cites W2786954262 @default.
• W3011566364 cites W2788087525 @default.
• W3011566364 cites W2796005422 @default.
• W3011566364 cites W2806186486 @default.
• W3011566364 cites W2883191879 @default.
• W3011566364 cites W2886165156 @default.
• W3011566364 cites W2888531326 @default.
• W3011566364 cites W2896682297 @default.
• W3011566364 cites W2897537410 @default.
• W3011566364 cites W2913778645 @default.
• W3011566364 cites W2952918110 @default.
• W3011566364 cites W2972224799 @default.
• W3011566364 cites W4249509226 @default.
• W3011566364 doi "https://doi.org/10.1002/cmdc.202000003" @default.
• W3011566364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32168421" @default.
• W3011566364 hasPublicationYear "2020" @default.
• W3011566364 type Work @default.
• W3011566364 sameAs 3011566364 @default.
• W3011566364 citedByCount "18" @default.
• W3011566364 countsByYear W30115663642020 @default.
• W3011566364 countsByYear W30115663642021 @default.
• W3011566364 countsByYear W30115663642022 @default.
• W3011566364 countsByYear W30115663642023 @default.
• W3011566364 crossrefType "journal-article" @default.
• W3011566364 hasAuthorship W3011566364A5005873881 @default.
• W3011566364 hasAuthorship W3011566364A5011976803 @default.
• W3011566364 hasAuthorship W3011566364A5036803810 @default.
• W3011566364 hasAuthorship W3011566364A5050648586 @default.
• W3011566364 hasAuthorship W3011566364A5074529781 @default.
• W3011566364 hasAuthorship W3011566364A5086244003 @default.
• W3011566364 hasConcept C12554922 @default.
• W3011566364 hasConcept C155672457 @default.
• W3011566364 hasConcept C15920480 @default.
• W3011566364 hasConcept C171250308 @default.
• W3011566364 hasConcept C178790620 @default.
• W3011566364 hasConcept C185592680 @default.
• W3011566364 hasConcept C192562407 @default.
• W3011566364 hasConcept C197404232 @default.
• W3011566364 hasConcept C21951064 @default.
• W3011566364 hasConcept C2778978742 @default.
• W3011566364 hasConcept C521977710 @default.
• W3011566364 hasConcept C67407626 @default.
• W3011566364 hasConcept C86803240 @default.
• W3011566364 hasConceptScore W3011566364C12554922 @default.
• W3011566364 hasConceptScore W3011566364C155672457 @default.
• W3011566364 hasConceptScore W3011566364C15920480 @default.
• W3011566364 hasConceptScore W3011566364C171250308 @default.
• W3011566364 hasConceptScore W3011566364C178790620 @default.
• W3011566364 hasConceptScore W3011566364C185592680 @default.
• W3011566364 hasConceptScore W3011566364C192562407 @default.
• W3011566364 hasConceptScore W3011566364C197404232 @default.
• W3011566364 hasConceptScore W3011566364C21951064 @default.
• W3011566364 hasConceptScore W3011566364C2778978742 @default.
• W3011566364 hasConceptScore W3011566364C521977710 @default.
• W3011566364 hasConceptScore W3011566364C67407626 @default.
• W3011566364 hasConceptScore W3011566364C86803240 @default.
• W3011566364 hasFunder F4320306076 @default.
• W3011566364 hasFunder F4320332161 @default.
• W3011566364 hasFunder F4320332641 @default.
• W3011566364 hasIssue "12" @default.
• W3011566364 hasLocation W30115663641 @default.
• W3011566364 hasOpenAccess W3011566364 @default.

• next