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- W3011756564 abstract "Abstract Introduction Using a large national registry, we investigated patterns of care and overall survival (OS) for metastatic rectal cancer patients treated with chemotherapy or radiotherapy (RT), or with a multimodal approach. Patients and Methods Adult patients with metastatic rectal cancer who did not undergo resection diagnosed from 2004 to 2014 were included. Kaplan-Meier, log-rank, and Cox regression analyses were performed. Results We identified 2385 patients. Of these, 1020 patients (43%) received chemotherapy alone, 228 (10%) received RT alone, 850 (36%) received chemotherapy and RT, and 287 (12%) received no treatment. Receipt of chemotherapy alone increased over the study period, and receipt of chemoradiotherapy decreased (P Conclusion Metastatic rectal cancer patients with T3 tumors were more likely to receive RT. Local RT does not improve survival for patients with metastatic rectal cancer who do not also undergo surgery. The use of chemotherapy alone for metastatic rectal cancer is increasing, and chemotherapy is associated with higher OS compared to no treatment and RT alone. This remained true even in patients older than 80 years." @default.
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- W3011756564 date "2020-06-01" @default.
- W3011756564 modified "2023-09-24" @default.
- W3011756564 title "Analysis of Nonsurgical Treatment Options for Metastatic Rectal Cancer" @default.
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- W3011756564 doi "https://doi.org/10.1016/j.clcc.2019.11.002" @default.
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