Matches in SemOpenAlex for { <https://semopenalex.org/work/W3011819571> ?p ?o ?g. }
- W3011819571 endingPage "78" @default.
- W3011819571 startingPage "70" @default.
- W3011819571 abstract "Background Gastroesophageal reflux disease (GERD) is a common disease with various clinical presentations. Acid suppression with proton pump inhibitors and lifestyle modification may not lead to satisfactory response in a substantial portion of patients. We investigated the possible effect of midodrine in patients with refractory GERD. Methods Patients suffering from GERD and were refractory to one-month course of pantoprazole 40mg twice daily entered the study. This was a pilot, randomized, double-blind, and placebo-controlled study. After randomization, one group received Midodrine 5mg before meals for one month, and the other group received placebo for the same period. Meanwhile, pantoprazole was continued 40mg twice daily in both arms. The severity of symptoms was evaluated by the visual scoring system. Quality of life (QoL) in both groups was measured using a standardized version of Quality of Life in Reflux and Dyspepsia questionnaire (QOLRAD). Results A total of twenty patients were enrolled in this study. There was a significant interaction between the groups and time on all measured scores based on QOLRAD questionnaire. All the markers in the Midodrine group had significant improvement over time, but the placebo group did not show any significant improvement. Both visual severity score and total QoL score in Midodrine arm showed a U shape change during 6 weeks. Conclusions Midodrine before a meal could be useful in alleviating symptoms and improving QoL in the patients with refractory gastroesophageal disease." @default.
- W3011819571 created "2020-03-23" @default.
- W3011819571 creator A5004748156 @default.
- W3011819571 creator A5004919570 @default.
- W3011819571 creator A5006897146 @default.
- W3011819571 creator A5015280297 @default.
- W3011819571 creator A5016712562 @default.
- W3011819571 creator A5020128764 @default.
- W3011819571 creator A5032018720 @default.
- W3011819571 creator A5036993448 @default.
- W3011819571 creator A5049166261 @default.
- W3011819571 creator A5056866619 @default.
- W3011819571 creator A5069232073 @default.
- W3011819571 date "2020-03-19" @default.
- W3011819571 modified "2023-09-26" @default.
- W3011819571 title "A preliminary report on the use of Midodrine in treating refractory gastroesophageal disease: Randomized Double-Blind Controlled Trial." @default.
- W3011819571 cites W1517064514 @default.
- W3011819571 cites W1547895755 @default.
- W3011819571 cites W1621221558 @default.
- W3011819571 cites W1678891441 @default.
- W3011819571 cites W1897962374 @default.
- W3011819571 cites W1899691766 @default.
- W3011819571 cites W1926507110 @default.
- W3011819571 cites W1978516590 @default.
- W3011819571 cites W1984326232 @default.
- W3011819571 cites W1993706139 @default.
- W3011819571 cites W2040040183 @default.
- W3011819571 cites W2064646374 @default.
- W3011819571 cites W2064990595 @default.
- W3011819571 cites W2072925621 @default.
- W3011819571 cites W2077407052 @default.
- W3011819571 cites W2083625182 @default.
- W3011819571 cites W2083790189 @default.
- W3011819571 cites W2084264352 @default.
- W3011819571 cites W2084379496 @default.
- W3011819571 cites W2091402426 @default.
- W3011819571 cites W2094149744 @default.
- W3011819571 cites W2099999179 @default.
- W3011819571 cites W2114442699 @default.
- W3011819571 cites W2115100611 @default.
- W3011819571 cites W2124608582 @default.
- W3011819571 cites W2128639898 @default.
- W3011819571 cites W2132004673 @default.
- W3011819571 cites W2136650640 @default.
- W3011819571 cites W2140922220 @default.
- W3011819571 cites W2143285572 @default.
- W3011819571 cites W2156522371 @default.
- W3011819571 cites W2157108147 @default.
- W3011819571 cites W2158690779 @default.
- W3011819571 cites W2159239762 @default.
- W3011819571 cites W2159657819 @default.
- W3011819571 cites W2168168749 @default.
- W3011819571 cites W2244257686 @default.
- W3011819571 cites W2416329110 @default.
- W3011819571 cites W2601599603 @default.
- W3011819571 cites W2676655276 @default.
- W3011819571 cites W2738505756 @default.
- W3011819571 cites W2790723724 @default.
- W3011819571 doi "https://doi.org/10.23750/abm.v91i1.8486" @default.
- W3011819571 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7569571" @default.
- W3011819571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32191657" @default.
- W3011819571 hasPublicationYear "2020" @default.
- W3011819571 type Work @default.
- W3011819571 sameAs 3011819571 @default.
- W3011819571 citedByCount "0" @default.
- W3011819571 crossrefType "journal-article" @default.
- W3011819571 hasAuthorship W3011819571A5004748156 @default.
- W3011819571 hasAuthorship W3011819571A5004919570 @default.
- W3011819571 hasAuthorship W3011819571A5006897146 @default.
- W3011819571 hasAuthorship W3011819571A5015280297 @default.
- W3011819571 hasAuthorship W3011819571A5016712562 @default.
- W3011819571 hasAuthorship W3011819571A5020128764 @default.
- W3011819571 hasAuthorship W3011819571A5032018720 @default.
- W3011819571 hasAuthorship W3011819571A5036993448 @default.
- W3011819571 hasAuthorship W3011819571A5049166261 @default.
- W3011819571 hasAuthorship W3011819571A5056866619 @default.
- W3011819571 hasAuthorship W3011819571A5069232073 @default.
- W3011819571 hasConcept C121332964 @default.
- W3011819571 hasConcept C126322002 @default.
- W3011819571 hasConcept C142424586 @default.
- W3011819571 hasConcept C142724271 @default.
- W3011819571 hasConcept C159110408 @default.
- W3011819571 hasConcept C168563851 @default.
- W3011819571 hasConcept C202061045 @default.
- W3011819571 hasConcept C204243189 @default.
- W3011819571 hasConcept C204787440 @default.
- W3011819571 hasConcept C27081682 @default.
- W3011819571 hasConcept C2777014526 @default.
- W3011819571 hasConcept C2779134260 @default.
- W3011819571 hasConcept C2779951463 @default.
- W3011819571 hasConcept C2780081974 @default.
- W3011819571 hasConcept C2991744798 @default.
- W3011819571 hasConcept C43270747 @default.
- W3011819571 hasConcept C535046627 @default.
- W3011819571 hasConcept C71924100 @default.
- W3011819571 hasConcept C73787029 @default.
- W3011819571 hasConcept C84393581 @default.
- W3011819571 hasConcept C87355193 @default.