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• W3011823615 abstract "Malignant ascites changes the microenvironment of the peritoneal cavity and damages abdominal functional host cells such as interstitial cells of Cajal (ICC), causing gastrointestinal dysfunction and poor prognosis. Besides tumor cells, malignant ascites contains large numbers of lymphocytes and macrophagocytes. These inflammatory cells act as a 'double arrow' and it is not clear whether they cause injury to ICCs. Our study demonstrates the presence of T lymphocytes in malignant ascites and shows that these cells may have a critical role in inducing damage to ICC via Caspases and Fas/FasL. These inflammatory cells were contributory to gastric dysfunction in our GI tumor-induced ascites mouse models." @default.
• W3011823615 created "2020-03-23" @default.
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• W3011823615 date "2018-01-01" @default.
• W3011823615 modified "2023-09-27" @default.
• W3011823615 title "Relationship between infiltrating lymphocytes in cancerous ascites and dysfunction of Cajal mesenchymal cells in the small intestine." @default.
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• W3011823615 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6958188" @default.
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