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• W3011844695 abstract "The first total synthesis of the pro-resolving lipid mediator 7(S),12(R),13(S)-Resolvin T2 [7(S),12(R),13(S)-RvT2] and its 13(R)-epimer, derived from n-3 docosapentaenoic acid (n-3 DPA), are described. 7(S),12(R),13(S)-RvT2 and its 13(R)-epimer were obtained by total synthesis using a chiral pool strategy to introduce the chiral centers. C7 was generated from S-(−)-1,2,4-butanetriol in both molecules and the C12 and C13 centers were generated from L-(+)-ribose and D-(−)-arabinose respectively. Cis and trans-selective Wittig reactions, selective deprotections, and Dess-Martin periodinane oxidation were the key steps in the syntheses." @default.
• W3011844695 created "2020-03-23" @default.
• W3011844695 creator A5037918415 @default.
• W3011844695 creator A5059546138 @default.
• W3011844695 date "2020-05-01" @default.
• W3011844695 modified "2023-09-25" @default.
• W3011844695 title "First total synthesis of the pro-resolving lipid mediator 7(S),12(R),13(S)-Resolvin T2 and its 13(R)-epimer" @default.
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• W3011844695 doi "https://doi.org/10.1016/j.tetlet.2020.151857" @default.
• W3011844695 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7454203" @default.
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