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- W3012020177 endingPage "806" @default.
- W3012020177 startingPage "789" @default.
- W3012020177 abstract "Abstract Other than the final divisions that lead to a mature oocyst, all the developmental stages of Toxoplasma gondii reproduce inside a host cell. The particular niche they occupy is formed by an invagination of the host plasma membrane (HPM) during invasion, resulting in a parasitophorous vacuole (PV) within which the parasites will grow and divide. The PV is a special environment that presents the parasites with the opportunity to coopt host cell functions through the use of secreted “effectors.” The chapter by Lebrun et al. discusses how the PV is formed and how the PV membrane (PVM) is modified to be a crucial place of dialogue between parasite and host cell. In this chapter, we focus on the parasite effectors that are translocated either across the HPM during invasion or across the PVM once the parasites have taken up residence inside the cell. Those transiting across the HPM during invasion generally originate in the apical, club-shaped rhoptries, while those that cross the PVM after invasion originate in the parasite’s dense granules. The number of such identified effectors continues to grow as does the list of remarkable ways, in which they coopt host cell functions for the parasite’s own purposes. Finally, we also discuss the limited knowledge on how these two classes of effectors move across the various membranes they respectively transit." @default.
- W3012020177 created "2020-03-23" @default.
- W3012020177 creator A5053925806 @default.
- W3012020177 creator A5074210440 @default.
- W3012020177 date "2020-01-01" @default.
- W3012020177 modified "2023-09-26" @default.
- W3012020177 title "Effectors produced by rhoptries and dense granules: an intense conversation between parasite and host in many languages" @default.
- W3012020177 cites W1491008823 @default.
- W3012020177 cites W1571840817 @default.
- W3012020177 cites W1595279671 @default.
- W3012020177 cites W1926739413 @default.
- W3012020177 cites W1964706690 @default.
- W3012020177 cites W1966086728 @default.
- W3012020177 cites W1969766619 @default.
- W3012020177 cites W1971050822 @default.
- W3012020177 cites W1972586696 @default.
- W3012020177 cites W1974595623 @default.
- W3012020177 cites W1976712030 @default.
- W3012020177 cites W1976781467 @default.
- W3012020177 cites W1977693553 @default.
- W3012020177 cites W1978466652 @default.
- W3012020177 cites W1979106632 @default.
- W3012020177 cites W1979300255 @default.
- W3012020177 cites W1981066202 @default.
- W3012020177 cites W1983891891 @default.
- W3012020177 cites W1988758735 @default.
- W3012020177 cites W1991275192 @default.
- W3012020177 cites W1992935467 @default.
- W3012020177 cites W1993349714 @default.
- W3012020177 cites W1993484262 @default.
- W3012020177 cites W1996143581 @default.
- W3012020177 cites W1996355227 @default.
- W3012020177 cites W1997308847 @default.
- W3012020177 cites W1997313407 @default.
- W3012020177 cites W1998047654 @default.
- W3012020177 cites W1998615549 @default.
- W3012020177 cites W2000861996 @default.
- W3012020177 cites W2002961859 @default.
- W3012020177 cites W2003493907 @default.
- W3012020177 cites W2007833275 @default.
- W3012020177 cites W2012818965 @default.
- W3012020177 cites W2013891209 @default.
- W3012020177 cites W2015293161 @default.
- W3012020177 cites W2015703705 @default.
- W3012020177 cites W2021105093 @default.
- W3012020177 cites W2024639429 @default.
- W3012020177 cites W2026861452 @default.
- W3012020177 cites W2027073533 @default.
- W3012020177 cites W2033779889 @default.
- W3012020177 cites W2033972585 @default.
- W3012020177 cites W2041475318 @default.
- W3012020177 cites W2048171163 @default.
- W3012020177 cites W2048933815 @default.
- W3012020177 cites W2050263490 @default.
- W3012020177 cites W2052059236 @default.
- W3012020177 cites W2052301327 @default.
- W3012020177 cites W2059646159 @default.
- W3012020177 cites W2061123122 @default.
- W3012020177 cites W2061191162 @default.
- W3012020177 cites W2064261370 @default.
- W3012020177 cites W2068294387 @default.
- W3012020177 cites W2070763276 @default.
- W3012020177 cites W2072773040 @default.
- W3012020177 cites W2074177784 @default.
- W3012020177 cites W2074354155 @default.
- W3012020177 cites W2075680757 @default.
- W3012020177 cites W2083692164 @default.
- W3012020177 cites W2085705809 @default.
- W3012020177 cites W2090036244 @default.
- W3012020177 cites W2090349233 @default.
- W3012020177 cites W2093020034 @default.
- W3012020177 cites W2100868544 @default.
- W3012020177 cites W2104352786 @default.
- W3012020177 cites W2105911630 @default.
- W3012020177 cites W2106482095 @default.
- W3012020177 cites W2114241062 @default.
- W3012020177 cites W2117235669 @default.
- W3012020177 cites W2117873437 @default.
- W3012020177 cites W2118954525 @default.
- W3012020177 cites W2126000073 @default.
- W3012020177 cites W2130217467 @default.
- W3012020177 cites W2132572271 @default.
- W3012020177 cites W2136846968 @default.
- W3012020177 cites W2139496218 @default.
- W3012020177 cites W2142788740 @default.
- W3012020177 cites W2142939879 @default.
- W3012020177 cites W2145728129 @default.
- W3012020177 cites W2153249510 @default.
- W3012020177 cites W2153756387 @default.
- W3012020177 cites W2154767199 @default.
- W3012020177 cites W2155202238 @default.
- W3012020177 cites W2158113848 @default.
- W3012020177 cites W2162553455 @default.
- W3012020177 cites W2163814594 @default.
- W3012020177 cites W2164275380 @default.
- W3012020177 cites W2164792430 @default.
- W3012020177 cites W2166235742 @default.
- W3012020177 cites W2167925524 @default.