Matches in SemOpenAlex for { <https://semopenalex.org/work/W3012042016> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3012042016 abstract "Abstract This study was performed to investigate whether the lipofuscin formed within cardiomyocytes can be excluded by the myocardial tissue. We have provided indicators that can be used for future studies on anti-aging interventions. In the present study, the heart of a 5-month-old BALB/c mouse was obtained for resin embedding and ultra-thin sectioning. The specimens were observed under a Hitach 7500 transmission electron microscope, and the images were acquired using an XR401 side-insertion device. Lipofuscin granules are found abundantly in myocardial cells. Cardiomyocytes can excrete lipofuscin granules into the myocardial interstitium using capsule-like protrusions that are formed on the sarcolemma. These granules enter the myocardial interstitium and can be de-aggregated to form “membrane-like garbage”, which can pass from the myocardial stroma into the lumen of the vessel through its walls in the form of soluble fine particles through diffusion or endocytosis of capillaries. Smaller lipofuscin granules can pass through the walls of the vessels and enter the blood vessel lumen through the active transport function of the capillary endothelial cells. When the extended cytoplasmic end of macrophages and fibroblasts fuse with the endothelial cells, the lipofuscin granules or clumps found in the cells of the myocardial interstitium are transported to the capillary walls, and then, they are released into the lumen of the blood vessel by the endothelial cells. The myocardial tissues of mice have the ability to eliminate the lipofuscin produced in the cardiomyocytes into the myocardial blood circulation. Although there are several mechanisms through which the myocardial tissues release lipofuscin into the bloodstream, it is mainly carried out in the form of small, fine, soluble, continuous transport." @default.
- W3012042016 created "2020-03-23" @default.
- W3012042016 creator A5045080436 @default.
- W3012042016 creator A5060292356 @default.
- W3012042016 creator A5073090336 @default.
- W3012042016 creator A5073216396 @default.
- W3012042016 creator A5078373928 @default.
- W3012042016 date "2020-03-10" @default.
- W3012042016 modified "2023-10-15" @default.
- W3012042016 title "Observation of the Transport and Removal of Lipofuscin from the Mouse Myocardium using Transmission Electron Microscope" @default.
- W3012042016 cites W1538904872 @default.
- W3012042016 cites W1980076134 @default.
- W3012042016 cites W1985177979 @default.
- W3012042016 cites W1987558049 @default.
- W3012042016 cites W1992029192 @default.
- W3012042016 cites W2000146799 @default.
- W3012042016 cites W2006162913 @default.
- W3012042016 cites W2012221118 @default.
- W3012042016 cites W2018027031 @default.
- W3012042016 cites W2022754327 @default.
- W3012042016 cites W2023767769 @default.
- W3012042016 cites W2038027009 @default.
- W3012042016 cites W2049199904 @default.
- W3012042016 cites W2050304614 @default.
- W3012042016 cites W2072208356 @default.
- W3012042016 cites W2153211616 @default.
- W3012042016 cites W2318536322 @default.
- W3012042016 cites W2328372803 @default.
- W3012042016 cites W2593138956 @default.
- W3012042016 cites W2917333786 @default.
- W3012042016 cites W4231756003 @default.
- W3012042016 doi "https://doi.org/10.1101/2020.03.10.985507" @default.
- W3012042016 hasPublicationYear "2020" @default.
- W3012042016 type Work @default.
- W3012042016 sameAs 3012042016 @default.
- W3012042016 citedByCount "2" @default.
- W3012042016 countsByYear W30120420162020 @default.
- W3012042016 countsByYear W30120420162023 @default.
- W3012042016 crossrefType "posted-content" @default.
- W3012042016 hasAuthorship W3012042016A5045080436 @default.
- W3012042016 hasAuthorship W3012042016A5060292356 @default.
- W3012042016 hasAuthorship W3012042016A5073090336 @default.
- W3012042016 hasAuthorship W3012042016A5073216396 @default.
- W3012042016 hasAuthorship W3012042016A5078373928 @default.
- W3012042016 hasBestOaLocation W30120420161 @default.
- W3012042016 hasConcept C105702510 @default.
- W3012042016 hasConcept C12554922 @default.
- W3012042016 hasConcept C131631996 @default.
- W3012042016 hasConcept C142724271 @default.
- W3012042016 hasConcept C1491633281 @default.
- W3012042016 hasConcept C185592680 @default.
- W3012042016 hasConcept C186198217 @default.
- W3012042016 hasConcept C28005876 @default.
- W3012042016 hasConcept C55493867 @default.
- W3012042016 hasConcept C71924100 @default.
- W3012042016 hasConcept C86803240 @default.
- W3012042016 hasConcept C95444343 @default.
- W3012042016 hasConceptScore W3012042016C105702510 @default.
- W3012042016 hasConceptScore W3012042016C12554922 @default.
- W3012042016 hasConceptScore W3012042016C131631996 @default.
- W3012042016 hasConceptScore W3012042016C142724271 @default.
- W3012042016 hasConceptScore W3012042016C1491633281 @default.
- W3012042016 hasConceptScore W3012042016C185592680 @default.
- W3012042016 hasConceptScore W3012042016C186198217 @default.
- W3012042016 hasConceptScore W3012042016C28005876 @default.
- W3012042016 hasConceptScore W3012042016C55493867 @default.
- W3012042016 hasConceptScore W3012042016C71924100 @default.
- W3012042016 hasConceptScore W3012042016C86803240 @default.
- W3012042016 hasConceptScore W3012042016C95444343 @default.
- W3012042016 hasLocation W30120420161 @default.
- W3012042016 hasOpenAccess W3012042016 @default.
- W3012042016 hasPrimaryLocation W30120420161 @default.
- W3012042016 hasRelatedWork W1985870115 @default.
- W3012042016 hasRelatedWork W2003417689 @default.
- W3012042016 hasRelatedWork W2006162913 @default.
- W3012042016 hasRelatedWork W2007971923 @default.
- W3012042016 hasRelatedWork W2038684666 @default.
- W3012042016 hasRelatedWork W2169314708 @default.
- W3012042016 hasRelatedWork W3009289062 @default.
- W3012042016 hasRelatedWork W807746960 @default.
- W3012042016 hasRelatedWork W80844995 @default.
- W3012042016 hasRelatedWork W95357468 @default.
- W3012042016 isParatext "false" @default.
- W3012042016 isRetracted "false" @default.
- W3012042016 magId "3012042016" @default.
- W3012042016 workType "article" @default.