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- W3012145864 abstract "Titanium and its alloys are widely used as implant in biomedical applications. Theyhave good mechanical and chemical properties, biocompatibility and biointegrationwith human body, but they have no ability to bond directly to natural bone. Therefore,alkali and heat treatments (gel oxidation) were introduced to improve the bioactivityof titanium by forming a mixture of sodium titanate and rutile on the surface oftitanium. This method enables titanium to possess a bioactive surface which isessential to induce the apatite formation. This study aims to investigate the effects ofalkali, sodium removal and heat treatments on in vitro bioactivity of titanium. UV lightirradiation was used to study the effect on in vitro bioactivity of titanium. Alkalitreatedtitanium subjected to heat treatment in air have shown better overall in vitroperformance than those treated in argon atmosphere. Therefore, the sodium removaltreatment (dilute hydrochloric acid (HCl) treatment) was introduced to convert sodiumtitanate into anatase to improve the bioactivity of titanium treated in argon atmosphere.Thus, four samples (AT-0.5-HT500R, AT-0.5-HT600R, AT-5-HT500R and AT-5-HT600R) with different ratios of anatase to rutile were produced by varying theconcentration of HCl acid treatment and heating temperature in argon atmosphere. Itwas found that the incorporation of sodium removal treatment has reduced two timesthe duration of apatite formation as compared with the conventional alkali and heattreatments. In order to further enhance the bioactivity, these samples were subjectedto six different conditions of ultraviolet light irradiation and followed by in vitrobioactivity test. As a result, AT-5-HT500R (82.2% anatase and 17.8% rutile) wasproven to deliver the best performance. It was confirmed that UV light irradiationenhances the bioactivity by removing hydrocarbon, inducing superhydrophilicity andforming OH groups. It was discovered that the duration of apatite formation wasshortened to 7 days. Furthermore, the continuous UVA irradiation during in vitro testresulted in the acceleration of bonelike apatite formation in 3 days. It can be concludedthat the sodium removal treatment and UV light irradiation give very significant impact to the formation of bonelike apatite on the titanium surfaces for biomedicalapplications." @default.
- W3012145864 created "2020-03-23" @default.
- W3012145864 creator A5068874194 @default.
- W3012145864 date "2018-06-01" @default.
- W3012145864 modified "2023-09-27" @default.
- W3012145864 title "Preparation of bioactive surface via gel oxidation on titanium for biomedical application (hip joint replacement)" @default.
- W3012145864 hasPublicationYear "2018" @default.
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