FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3012357488> ?p ?o ?g. }

• W3012357488 endingPage "126" @default.
• W3012357488 startingPage "126" @default.
• W3012357488 abstract "The cellular immune responses elicited by an investigational vaccine against an emergent variant of influenza (H3N2v) are not fully understood. Twenty-five subjects, enrolled in an investigational influenza A/H3N2v vaccine study, who received two doses of vaccine 21 days apart, were included in a sub-study of cellular immune responses. H3N2v-specific plasmablasts were determined by ELISpot 8 days after each vaccine dose and H3N2v specific CD4+ T cells were quantified by intracellular cytokine and CD154 (CD40 ligand) staining before vaccination, 8 and 21 days after each vaccine dose. Results: 95% (19/20) and 96% (24/25) subjects had pre-existing H3N2v specific memory B, and T cell responses, respectively. Plasmablast responses at Day 8 after the first vaccine administration were detected against contemporary H3N2 strains and correlated with hemagglutination inhibition HAI (IgG: p = 0.018; IgA: p < 0.001) and Neut (IgG: p = 0.038; IgA: p = 0.021) titers and with memory B cell frequency at baseline (IgA: r = 0.76, p < 0.001; IgG: r = 0.74, p = 0.0001). The CD4+ T cells at Days 8 and 21 expanded after prime vaccination and this expansion correlated strongly with early post-vaccination HAI and Neut titers (p ≤ 0.002). In an adult population, the rapid serological response observed after initial H3N2v vaccination correlates with post-vaccination plasmablasts and CD4+ T cell responses." @default.
• W3012357488 created "2020-03-23" @default.
• W3012357488 creator A5005432740 @default.
• W3012357488 creator A5012154124 @default.
• W3012357488 creator A5016037005 @default.
• W3012357488 creator A5040846880 @default.
• W3012357488 creator A5041183761 @default.
• W3012357488 creator A5041415448 @default.
• W3012357488 creator A5047942140 @default.
• W3012357488 creator A5050849376 @default.
• W3012357488 creator A5057786429 @default.
• W3012357488 creator A5064116200 @default.
• W3012357488 creator A5069889761 @default.
• W3012357488 creator A5079489250 @default.
• W3012357488 creator A5081113436 @default.
• W3012357488 creator A5081646689 @default.
• W3012357488 date "2020-03-13" @default.
• W3012357488 modified "2023-10-16" @default.
• W3012357488 title "Baseline Levels of Influenza-Specific B Cells and T Cell Responses Modulate Human Immune Responses to Swine Variant Influenza A/H3N2 Vaccine" @default.
• W3012357488 cites W1990429464 @default.
• W3012357488 cites W1994200209 @default.
• W3012357488 cites W2018239119 @default.
• W3012357488 cites W2036182565 @default.
• W3012357488 cites W2038899530 @default.
• W3012357488 cites W2039333054 @default.
• W3012357488 cites W2057566115 @default.
• W3012357488 cites W2061397586 @default.
• W3012357488 cites W2070141423 @default.
• W3012357488 cites W2084806839 @default.
• W3012357488 cites W2093138102 @default.
• W3012357488 cites W2096187131 @default.
• W3012357488 cites W2110586663 @default.
• W3012357488 cites W2137984836 @default.
• W3012357488 cites W2155467153 @default.
• W3012357488 cites W2158071105 @default.
• W3012357488 cites W2164655171 @default.
• W3012357488 cites W2166559731 @default.
• W3012357488 cites W2432225738 @default.
• W3012357488 cites W2464515200 @default.
• W3012357488 cites W2508296694 @default.
• W3012357488 cites W2521413867 @default.
• W3012357488 cites W2964972272 @default.
• W3012357488 doi "https://doi.org/10.3390/vaccines8010126" @default.
• W3012357488 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7157591" @default.
• W3012357488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32183105" @default.
• W3012357488 hasPublicationYear "2020" @default.
• W3012357488 type Work @default.
• W3012357488 sameAs 3012357488 @default.
• W3012357488 citedByCount "1" @default.
• W3012357488 countsByYear W30123574882022 @default.
• W3012357488 crossrefType "journal-article" @default.
• W3012357488 hasAuthorship W3012357488A5005432740 @default.
• W3012357488 hasAuthorship W3012357488A5012154124 @default.
• W3012357488 hasAuthorship W3012357488A5016037005 @default.
• W3012357488 hasAuthorship W3012357488A5040846880 @default.
• W3012357488 hasAuthorship W3012357488A5041183761 @default.
• W3012357488 hasAuthorship W3012357488A5041415448 @default.
• W3012357488 hasAuthorship W3012357488A5047942140 @default.
• W3012357488 hasAuthorship W3012357488A5050849376 @default.
• W3012357488 hasAuthorship W3012357488A5057786429 @default.
• W3012357488 hasAuthorship W3012357488A5064116200 @default.
• W3012357488 hasAuthorship W3012357488A5069889761 @default.
• W3012357488 hasAuthorship W3012357488A5079489250 @default.
• W3012357488 hasAuthorship W3012357488A5081113436 @default.
• W3012357488 hasAuthorship W3012357488A5081646689 @default.
• W3012357488 hasBestOaLocation W30123574881 @default.
• W3012357488 hasConcept C154317977 @default.
• W3012357488 hasConcept C159047783 @default.
• W3012357488 hasConcept C159654299 @default.
• W3012357488 hasConcept C182072434 @default.
• W3012357488 hasConcept C202751555 @default.
• W3012357488 hasConcept C203014093 @default.
• W3012357488 hasConcept C22070199 @default.
• W3012357488 hasConcept C2776090121 @default.
• W3012357488 hasConcept C2778453870 @default.
• W3012357488 hasConcept C2779053233 @default.
• W3012357488 hasConcept C2779234475 @default.
• W3012357488 hasConcept C2779359726 @default.
• W3012357488 hasConcept C2780689484 @default.
• W3012357488 hasConcept C2908647359 @default.
• W3012357488 hasConcept C32611913 @default.
• W3012357488 hasConcept C39347974 @default.
• W3012357488 hasConcept C55493867 @default.
• W3012357488 hasConcept C71924100 @default.
• W3012357488 hasConcept C86803240 @default.
• W3012357488 hasConcept C8891405 @default.
• W3012357488 hasConcept C99454951 @default.
• W3012357488 hasConceptScore W3012357488C154317977 @default.
• W3012357488 hasConceptScore W3012357488C159047783 @default.
• W3012357488 hasConceptScore W3012357488C159654299 @default.
• W3012357488 hasConceptScore W3012357488C182072434 @default.
• W3012357488 hasConceptScore W3012357488C202751555 @default.
• W3012357488 hasConceptScore W3012357488C203014093 @default.
• W3012357488 hasConceptScore W3012357488C22070199 @default.
• W3012357488 hasConceptScore W3012357488C2776090121 @default.
• W3012357488 hasConceptScore W3012357488C2778453870 @default.
• W3012357488 hasConceptScore W3012357488C2779053233 @default.
• W3012357488 hasConceptScore W3012357488C2779234475 @default.

• next