FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3012404258> ?p ?o ?g. }

• W3012404258 endingPage "1225" @default.
• W3012404258 startingPage "1215" @default.
• W3012404258 abstract "Inspired by the structure and function of the mussel adhesive protein, a facile strategy involving oxidative polymerization of dopamine was proposed for surface modification of nanostructured lipid carriers (NLCs) to promote drug delivery in the skin. The formation of a polydopamine (PDA) layer rounding the surface of NLCs was confirmed by the X-ray photoelectron spectroscopy and the Fourier transform infrared spectroscopy studies. Using terbinafine (TBF) as a model drug, the in vitro permeation study revealed that the PDA coating significantly enhanced the delivery of TBF from NLCs to the deep skin layers, where the follicular pathway played an essential role as suggested by the hair follicle blocking and differential tape stripping experiments, as well as the laser scanning confocal microscopy study by using Nile red as the fluorescent probe. The cellular investigation indicated that the PDA coating led to a higher cellular uptake of nanoparticles in human immortalized keratinocytes (HaCaT) without causing additional cytotoxicity. Using endocytic inhibitors, it was found that the lipid raft/caveolae-mediated endocytosis was strongly involved in the internalization of both the PDA modified and unmodified NLCs. Our results suggested that surface modification of NLCs with PDA coating improved the intracutaneous drug delivery mainly via the follicular pathway, which provided an avenue for the development of potential drug delivery carriers for dermal use." @default.
• W3012404258 created "2020-03-23" @default.
• W3012404258 creator A5016535802 @default.
• W3012404258 creator A5034790559 @default.
• W3012404258 creator A5063880073 @default.
• W3012404258 creator A5069136110 @default.
• W3012404258 creator A5086231834 @default.
• W3012404258 date "2020-03-13" @default.
• W3012404258 modified "2023-10-11" @default.
• W3012404258 title "Mussel-Inspired Polydopamine Coating Enhances the Intracutaneous Drug Delivery from Nanostructured Lipid Carriers Dependently on a Follicular Pathway" @default.
• W3012404258 cites W1734250133 @default.
• W3012404258 cites W1846505747 @default.
• W3012404258 cites W1964501217 @default.
• W3012404258 cites W1974123834 @default.
• W3012404258 cites W1983714457 @default.
• W3012404258 cites W1996833161 @default.
• W3012404258 cites W2002528172 @default.
• W3012404258 cites W2004468483 @default.
• W3012404258 cites W2011667484 @default.
• W3012404258 cites W2013262011 @default.
• W3012404258 cites W2021167843 @default.
• W3012404258 cites W2022087048 @default.
• W3012404258 cites W2046088979 @default.
• W3012404258 cites W2046454400 @default.
• W3012404258 cites W2047247630 @default.
• W3012404258 cites W2048711631 @default.
• W3012404258 cites W2051425346 @default.
• W3012404258 cites W2059549594 @default.
• W3012404258 cites W2072344392 @default.
• W3012404258 cites W2072656690 @default.
• W3012404258 cites W2084538675 @default.
• W3012404258 cites W2113972541 @default.
• W3012404258 cites W2124434163 @default.
• W3012404258 cites W2152312983 @default.
• W3012404258 cites W2173044124 @default.
• W3012404258 cites W2283944724 @default.
• W3012404258 cites W2335405043 @default.
• W3012404258 cites W2338603586 @default.
• W3012404258 cites W2516001258 @default.
• W3012404258 cites W2566666513 @default.
• W3012404258 cites W2581007089 @default.
• W3012404258 cites W2610893933 @default.
• W3012404258 cites W2616030447 @default.
• W3012404258 cites W2767390274 @default.
• W3012404258 cites W2785875427 @default.
• W3012404258 cites W2801831449 @default.
• W3012404258 cites W2849832964 @default.
• W3012404258 cites W2913692542 @default.
• W3012404258 cites W2953212384 @default.
• W3012404258 cites W2962103572 @default.
• W3012404258 cites W2964585156 @default.
• W3012404258 cites W854625900 @default.
• W3012404258 doi "https://doi.org/10.1021/acs.molpharmaceut.9b01240" @default.
• W3012404258 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32167771" @default.
• W3012404258 hasPublicationYear "2020" @default.
• W3012404258 type Work @default.
• W3012404258 sameAs 3012404258 @default.
• W3012404258 citedByCount "16" @default.
• W3012404258 countsByYear W30124042582020 @default.
• W3012404258 countsByYear W30124042582021 @default.
• W3012404258 countsByYear W30124042582022 @default.
• W3012404258 countsByYear W30124042582023 @default.
• W3012404258 crossrefType "journal-article" @default.
• W3012404258 hasAuthorship W3012404258A5016535802 @default.
• W3012404258 hasAuthorship W3012404258A5034790559 @default.
• W3012404258 hasAuthorship W3012404258A5063880073 @default.
• W3012404258 hasAuthorship W3012404258A5069136110 @default.
• W3012404258 hasAuthorship W3012404258A5086231834 @default.
• W3012404258 hasConcept C115537861 @default.
• W3012404258 hasConcept C118995209 @default.
• W3012404258 hasConcept C12554922 @default.
• W3012404258 hasConcept C13245373 @default.
• W3012404258 hasConcept C142724271 @default.
• W3012404258 hasConcept C147789679 @default.
• W3012404258 hasConcept C1491633281 @default.
• W3012404258 hasConcept C171250308 @default.
• W3012404258 hasConcept C178790620 @default.
• W3012404258 hasConcept C18150654 @default.
• W3012404258 hasConcept C185592680 @default.
• W3012404258 hasConcept C192562407 @default.
• W3012404258 hasConcept C202751555 @default.
• W3012404258 hasConcept C2778370115 @default.
• W3012404258 hasConcept C2779820397 @default.
• W3012404258 hasConcept C28005876 @default.
• W3012404258 hasConcept C55493867 @default.
• W3012404258 hasConcept C71924100 @default.
• W3012404258 hasConcept C79747257 @default.
• W3012404258 hasConcept C86803240 @default.
• W3012404258 hasConceptScore W3012404258C115537861 @default.
• W3012404258 hasConceptScore W3012404258C118995209 @default.
• W3012404258 hasConceptScore W3012404258C12554922 @default.
• W3012404258 hasConceptScore W3012404258C13245373 @default.
• W3012404258 hasConceptScore W3012404258C142724271 @default.
• W3012404258 hasConceptScore W3012404258C147789679 @default.
• W3012404258 hasConceptScore W3012404258C1491633281 @default.
• W3012404258 hasConceptScore W3012404258C171250308 @default.
• W3012404258 hasConceptScore W3012404258C178790620 @default.
• W3012404258 hasConceptScore W3012404258C18150654 @default.

• next