Matches in SemOpenAlex for { <https://semopenalex.org/work/W3012485859> ?p ?o ?g. }
- W3012485859 endingPage "295" @default.
- W3012485859 startingPage "295" @default.
- W3012485859 abstract "In this review, we highlight information on microRNA (miRNA) identification and functional characterization in the beef for muscle and carcass composition traits, with an emphasis on Qinchuan beef cattle, and discuss the current challenges and future directions for the use of miRNA as a biomarker in cattle for breeding programs to improve meat quality and carcass traits. MicroRNAs are endogenous and non-coding RNA that have the function of making post-transcriptional modifications during the process of preadipocyte differentiation in mammals. Many studies claim that diverse miRNAs have an impact on adipogenesis. Furthermore, their target genes are associated with every phase of adipocyte differentiation. It has been confirmed that, during adipogenesis, several miRNAs are differentially expressed, including miR-204, miR-224, and miR-33. The development of mammalian skeletal muscle is sequentially controlled by somite commitment into progenitor cells, followed by their fusion and migration, the proliferation of myoblasts, and final modification into fast- and slow-twitch muscle fibers. It has been reported that miRNA in the bovine MEG3-DIO3 locus has a regulatory function for myoblast differentiation. Likewise, miR-224 has been associated with controlling the differentiation of bovine adipocytes by targeting lipoprotein lipase. Through the posttranscriptional downregulation of KLF6, miR-148a-3p disrupts the proliferation of bovine myoblasts and stimulates apoptosis while the miR-23a~27a~24-2 cluster represses adipogenesis. Additional to influences on muscle and fat, bta-mir-182, bta-mir-183, and bta-mir-338 represent regulators of proteolysis in muscle, which influences meat tenderness." @default.
- W3012485859 created "2020-03-23" @default.
- W3012485859 creator A5014825255 @default.
- W3012485859 creator A5015175387 @default.
- W3012485859 creator A5020387919 @default.
- W3012485859 creator A5031922956 @default.
- W3012485859 creator A5047274929 @default.
- W3012485859 creator A5054256557 @default.
- W3012485859 creator A5061254569 @default.
- W3012485859 creator A5061392895 @default.
- W3012485859 creator A5068600177 @default.
- W3012485859 creator A5069506329 @default.
- W3012485859 creator A5089772471 @default.
- W3012485859 date "2020-03-11" @default.
- W3012485859 modified "2023-10-15" @default.
- W3012485859 title "The Role of MicroRNAs in Muscle Tissue Development in Beef Cattle" @default.
- W3012485859 cites W179241959 @default.
- W3012485859 cites W1819171550 @default.
- W3012485859 cites W1952579501 @default.
- W3012485859 cites W1965084904 @default.
- W3012485859 cites W1974321250 @default.
- W3012485859 cites W1986903527 @default.
- W3012485859 cites W1994264655 @default.
- W3012485859 cites W1997529197 @default.
- W3012485859 cites W1999307118 @default.
- W3012485859 cites W2001508508 @default.
- W3012485859 cites W2003166113 @default.
- W3012485859 cites W2004916086 @default.
- W3012485859 cites W2006792851 @default.
- W3012485859 cites W2010384402 @default.
- W3012485859 cites W2023398004 @default.
- W3012485859 cites W2039191702 @default.
- W3012485859 cites W2046737464 @default.
- W3012485859 cites W2047461181 @default.
- W3012485859 cites W2056051702 @default.
- W3012485859 cites W2066028026 @default.
- W3012485859 cites W2067228453 @default.
- W3012485859 cites W2070571588 @default.
- W3012485859 cites W2073567151 @default.
- W3012485859 cites W2077012773 @default.
- W3012485859 cites W2082924833 @default.
- W3012485859 cites W2085024815 @default.
- W3012485859 cites W2091850057 @default.
- W3012485859 cites W2091895695 @default.
- W3012485859 cites W2095734937 @default.
- W3012485859 cites W2113047680 @default.
- W3012485859 cites W2114395071 @default.
- W3012485859 cites W2116902247 @default.
- W3012485859 cites W2124221912 @default.
- W3012485859 cites W2134158036 @default.
- W3012485859 cites W2134406094 @default.
- W3012485859 cites W2142342028 @default.
- W3012485859 cites W2144735576 @default.
- W3012485859 cites W2153899636 @default.
- W3012485859 cites W2158992273 @default.
- W3012485859 cites W2159303054 @default.
- W3012485859 cites W2161864879 @default.
- W3012485859 cites W2164079778 @default.
- W3012485859 cites W2168230240 @default.
- W3012485859 cites W2171694179 @default.
- W3012485859 cites W2272197615 @default.
- W3012485859 cites W2278997977 @default.
- W3012485859 cites W2501671595 @default.
- W3012485859 cites W2593197658 @default.
- W3012485859 cites W2597827012 @default.
- W3012485859 cites W2604216480 @default.
- W3012485859 cites W2606397279 @default.
- W3012485859 cites W2614002269 @default.
- W3012485859 cites W2739533874 @default.
- W3012485859 cites W2748414394 @default.
- W3012485859 cites W2765505237 @default.
- W3012485859 cites W2790974348 @default.
- W3012485859 cites W2795273851 @default.
- W3012485859 cites W2802375498 @default.
- W3012485859 cites W2807553218 @default.
- W3012485859 cites W2897397885 @default.
- W3012485859 cites W2901123376 @default.
- W3012485859 cites W2905392225 @default.
- W3012485859 cites W2908509300 @default.
- W3012485859 cites W2913951443 @default.
- W3012485859 cites W2917021347 @default.
- W3012485859 cites W2917129046 @default.
- W3012485859 cites W2936212010 @default.
- W3012485859 cites W2948762819 @default.
- W3012485859 cites W2951833150 @default.
- W3012485859 cites W4211064852 @default.
- W3012485859 cites W4243963808 @default.
- W3012485859 doi "https://doi.org/10.3390/genes11030295" @default.
- W3012485859 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7140828" @default.
- W3012485859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32168744" @default.
- W3012485859 hasPublicationYear "2020" @default.
- W3012485859 type Work @default.
- W3012485859 sameAs 3012485859 @default.
- W3012485859 citedByCount "31" @default.
- W3012485859 countsByYear W30124858592020 @default.
- W3012485859 countsByYear W30124858592021 @default.
- W3012485859 countsByYear W30124858592022 @default.
- W3012485859 countsByYear W30124858592023 @default.