Matches in SemOpenAlex for { <https://semopenalex.org/work/W3012742419> ?p ?o ?g. }
- W3012742419 endingPage "e582" @default.
- W3012742419 startingPage "e575" @default.
- W3012742419 abstract "Objectives: This study describes the hormone profiles for gonadal late effects after alkylator-based hematopoietic stem cell transplant (HSCT) regimens used for sickle-cell disease (SCD). Methods: This is a retrospective chart review of subjects followed in the post-HSCT clinic for sickle-cell disease. Patient demographics, pubertal development, characteristics of pre-HSCT disease severity, treatment before HSCT, conditioning regimens, presence of graft versus host disease and follicle-stimulating hormone, anti-Müllerian hormone (AMH), luteinizing hormone and testosterone were abstracted from the medical record. Results: Forty subjects (24 female individuals) with SCD were 9 (±4.3) years old at HSCT and 7.9 years (±5.6) from HSCT. At the time of transplant, 8% of female individuals and no male individuals were pubertal and 58% of female individuals and 38% of male individuals had been treated with hydroxyurea. Post-HSCT, all of the female individuals had diminished ovarian reserve on the basis of low AMH values and 10 of the pubertal female individuals (71%) had premature ovarian insufficiency defined as follicle-stimulating hormone >40 mIU/mL ×2. There was no ovarian recovery and AMH remained very low or undetectable up to 13 years post-HSCT. In male individuals, luteinizing hormone and testosterone levels were normal for age. Conclusions: Post-HSCT for SCD, all female individuals had diminished ovarian reserve and most female individuals had POI, whereas male individuals had normal testosterone hormone production." @default.
- W3012742419 created "2020-03-27" @default.
- W3012742419 creator A5017265867 @default.
- W3012742419 creator A5063557553 @default.
- W3012742419 creator A5077259938 @default.
- W3012742419 creator A5081419587 @default.
- W3012742419 creator A5081473405 @default.
- W3012742419 creator A5087007852 @default.
- W3012742419 date "2020-03-20" @default.
- W3012742419 modified "2023-10-11" @default.
- W3012742419 title "Longitudinal Description of Gonadal Function in Sickle-cell Patients Treated With Hematopoietic Stem Cell Transplant Using Alkylator-based Conditioning Regimens" @default.
- W3012742419 cites W1590229730 @default.
- W3012742419 cites W1839076539 @default.
- W3012742419 cites W1901858058 @default.
- W3012742419 cites W1964202414 @default.
- W3012742419 cites W1974274088 @default.
- W3012742419 cites W1980048890 @default.
- W3012742419 cites W1987823938 @default.
- W3012742419 cites W1999077488 @default.
- W3012742419 cites W2000187706 @default.
- W3012742419 cites W2001065516 @default.
- W3012742419 cites W2002791371 @default.
- W3012742419 cites W2012818193 @default.
- W3012742419 cites W2014086006 @default.
- W3012742419 cites W2019583814 @default.
- W3012742419 cites W2021296266 @default.
- W3012742419 cites W2021688469 @default.
- W3012742419 cites W2028135932 @default.
- W3012742419 cites W2032423016 @default.
- W3012742419 cites W2036724879 @default.
- W3012742419 cites W2038697609 @default.
- W3012742419 cites W2039291692 @default.
- W3012742419 cites W2049091575 @default.
- W3012742419 cites W2053941291 @default.
- W3012742419 cites W2056855884 @default.
- W3012742419 cites W2057331844 @default.
- W3012742419 cites W2060481605 @default.
- W3012742419 cites W2070348012 @default.
- W3012742419 cites W2075293740 @default.
- W3012742419 cites W2076457632 @default.
- W3012742419 cites W2076575287 @default.
- W3012742419 cites W2079796390 @default.
- W3012742419 cites W2108915340 @default.
- W3012742419 cites W2109474968 @default.
- W3012742419 cites W2111668625 @default.
- W3012742419 cites W2115798190 @default.
- W3012742419 cites W2119533233 @default.
- W3012742419 cites W2131891646 @default.
- W3012742419 cites W2144504411 @default.
- W3012742419 cites W2149503337 @default.
- W3012742419 cites W2167241499 @default.
- W3012742419 cites W2171611684 @default.
- W3012742419 cites W2318407007 @default.
- W3012742419 cites W2334263927 @default.
- W3012742419 cites W2362542081 @default.
- W3012742419 cites W2414601706 @default.
- W3012742419 cites W2482801690 @default.
- W3012742419 cites W2490064445 @default.
- W3012742419 cites W2558024815 @default.
- W3012742419 cites W2588114258 @default.
- W3012742419 cites W2761047277 @default.
- W3012742419 cites W2894667403 @default.
- W3012742419 cites W4243745865 @default.
- W3012742419 cites W4317928731 @default.
- W3012742419 cites W4361745875 @default.
- W3012742419 doi "https://doi.org/10.1097/mph.0000000000001782" @default.
- W3012742419 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32205784" @default.
- W3012742419 hasPublicationYear "2020" @default.
- W3012742419 type Work @default.
- W3012742419 sameAs 3012742419 @default.
- W3012742419 citedByCount "17" @default.
- W3012742419 countsByYear W30127424192021 @default.
- W3012742419 countsByYear W30127424192022 @default.
- W3012742419 countsByYear W30127424192023 @default.
- W3012742419 crossrefType "journal-article" @default.
- W3012742419 hasAuthorship W3012742419A5017265867 @default.
- W3012742419 hasAuthorship W3012742419A5063557553 @default.
- W3012742419 hasAuthorship W3012742419A5077259938 @default.
- W3012742419 hasAuthorship W3012742419A5081419587 @default.
- W3012742419 hasAuthorship W3012742419A5081473405 @default.
- W3012742419 hasAuthorship W3012742419A5087007852 @default.
- W3012742419 hasConcept C126322002 @default.
- W3012742419 hasConcept C134018914 @default.
- W3012742419 hasConcept C2776600139 @default.
- W3012742419 hasConcept C2777408962 @default.
- W3012742419 hasConcept C2777688143 @default.
- W3012742419 hasConcept C2778575703 @default.
- W3012742419 hasConcept C2778780466 @default.
- W3012742419 hasConcept C2779234561 @default.
- W3012742419 hasConcept C2779279165 @default.
- W3012742419 hasConcept C2779279991 @default.
- W3012742419 hasConcept C2911091166 @default.
- W3012742419 hasConcept C42407357 @default.
- W3012742419 hasConcept C54355233 @default.
- W3012742419 hasConcept C71315377 @default.
- W3012742419 hasConcept C71924100 @default.
- W3012742419 hasConcept C86803240 @default.
- W3012742419 hasConceptScore W3012742419C126322002 @default.