Matches in SemOpenAlex for { <https://semopenalex.org/work/W3012912789> ?p ?o ?g. }
- W3012912789 endingPage "1979" @default.
- W3012912789 startingPage "1965" @default.
- W3012912789 abstract "Large-scale association analyses based on observational health care databases such as electronic health records have been a topic of increasing interest in the scientific community. However, challenges due to nonprobability sampling and phenotype misclassification associated with the use of these data sources are often ignored in standard analyses. The extent of the bias introduced by ignoring these factors is not well-characterized. In this paper, we develop an analytic framework for characterizing the bias expected in disease-gene association studies based on electronic health records when disease status misclassification and the sampling mechanism are ignored. Through a sensitivity analysis approach, this framework can be used to obtain plausible values for parameters of interest given summary results from standard analysis. We develop an online tool for performing this sensitivity analysis. Simulations demonstrate promising properties of the proposed method. We apply our approach to study bias in disease-gene association studies using electronic health record data from the Michigan Genomics Initiative, a longitudinal biorepository effort within The University Michigan health system." @default.
- W3012912789 created "2020-03-27" @default.
- W3012912789 creator A5004806713 @default.
- W3012912789 creator A5019297905 @default.
- W3012912789 creator A5082251592 @default.
- W3012912789 date "2020-03-20" @default.
- W3012912789 modified "2023-09-30" @default.
- W3012912789 title "An analytic framework for exploring sampling and observation process biases in genome and phenome‐wide association studies using electronic health records" @default.
- W3012912789 cites W1969857958 @default.
- W3012912789 cites W1982609346 @default.
- W3012912789 cites W1997338841 @default.
- W3012912789 cites W2068629909 @default.
- W3012912789 cites W2102215872 @default.
- W3012912789 cites W2106036991 @default.
- W3012912789 cites W2107369573 @default.
- W3012912789 cites W2113105800 @default.
- W3012912789 cites W2138162199 @default.
- W3012912789 cites W2148563768 @default.
- W3012912789 cites W2149750314 @default.
- W3012912789 cites W2169682586 @default.
- W3012912789 cites W2274048411 @default.
- W3012912789 cites W2551682144 @default.
- W3012912789 cites W2555058594 @default.
- W3012912789 cites W2760829732 @default.
- W3012912789 cites W2765828622 @default.
- W3012912789 cites W2771201185 @default.
- W3012912789 cites W2773666933 @default.
- W3012912789 cites W2782865667 @default.
- W3012912789 cites W2788633781 @default.
- W3012912789 cites W2791246728 @default.
- W3012912789 cites W2803332630 @default.
- W3012912789 cites W2809403876 @default.
- W3012912789 cites W2890017919 @default.
- W3012912789 doi "https://doi.org/10.1002/sim.8524" @default.
- W3012912789 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32198773" @default.
- W3012912789 hasPublicationYear "2020" @default.
- W3012912789 type Work @default.
- W3012912789 sameAs 3012912789 @default.
- W3012912789 citedByCount "11" @default.
- W3012912789 countsByYear W30129127892019 @default.
- W3012912789 countsByYear W30129127892020 @default.
- W3012912789 countsByYear W30129127892021 @default.
- W3012912789 countsByYear W30129127892022 @default.
- W3012912789 countsByYear W30129127892023 @default.
- W3012912789 crossrefType "journal-article" @default.
- W3012912789 hasAuthorship W3012912789A5004806713 @default.
- W3012912789 hasAuthorship W3012912789A5019297905 @default.
- W3012912789 hasAuthorship W3012912789A5082251592 @default.
- W3012912789 hasBestOaLocation W30129127892 @default.
- W3012912789 hasConcept C104317684 @default.
- W3012912789 hasConcept C105795698 @default.
- W3012912789 hasConcept C106131492 @default.
- W3012912789 hasConcept C124101348 @default.
- W3012912789 hasConcept C129848803 @default.
- W3012912789 hasConcept C140779682 @default.
- W3012912789 hasConcept C141231307 @default.
- W3012912789 hasConcept C142853389 @default.
- W3012912789 hasConcept C15744967 @default.
- W3012912789 hasConcept C160735492 @default.
- W3012912789 hasConcept C162324750 @default.
- W3012912789 hasConcept C2522767166 @default.
- W3012912789 hasConcept C3019952477 @default.
- W3012912789 hasConcept C31972630 @default.
- W3012912789 hasConcept C33923547 @default.
- W3012912789 hasConcept C41008148 @default.
- W3012912789 hasConcept C50522688 @default.
- W3012912789 hasConcept C542102704 @default.
- W3012912789 hasConcept C54355233 @default.
- W3012912789 hasConcept C75917345 @default.
- W3012912789 hasConcept C7952369 @default.
- W3012912789 hasConcept C86803240 @default.
- W3012912789 hasConceptScore W3012912789C104317684 @default.
- W3012912789 hasConceptScore W3012912789C105795698 @default.
- W3012912789 hasConceptScore W3012912789C106131492 @default.
- W3012912789 hasConceptScore W3012912789C124101348 @default.
- W3012912789 hasConceptScore W3012912789C129848803 @default.
- W3012912789 hasConceptScore W3012912789C140779682 @default.
- W3012912789 hasConceptScore W3012912789C141231307 @default.
- W3012912789 hasConceptScore W3012912789C142853389 @default.
- W3012912789 hasConceptScore W3012912789C15744967 @default.
- W3012912789 hasConceptScore W3012912789C160735492 @default.
- W3012912789 hasConceptScore W3012912789C162324750 @default.
- W3012912789 hasConceptScore W3012912789C2522767166 @default.
- W3012912789 hasConceptScore W3012912789C3019952477 @default.
- W3012912789 hasConceptScore W3012912789C31972630 @default.
- W3012912789 hasConceptScore W3012912789C33923547 @default.
- W3012912789 hasConceptScore W3012912789C41008148 @default.
- W3012912789 hasConceptScore W3012912789C50522688 @default.
- W3012912789 hasConceptScore W3012912789C542102704 @default.
- W3012912789 hasConceptScore W3012912789C54355233 @default.
- W3012912789 hasConceptScore W3012912789C75917345 @default.
- W3012912789 hasConceptScore W3012912789C7952369 @default.
- W3012912789 hasConceptScore W3012912789C86803240 @default.
- W3012912789 hasFunder F4320306076 @default.
- W3012912789 hasIssue "14" @default.
- W3012912789 hasLocation W30129127891 @default.
- W3012912789 hasLocation W30129127892 @default.
- W3012912789 hasLocation W30129127893 @default.