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- W3012988067 abstract "Background and purpose: Candidiasis is an opportunistic infection caused by Candida species which occurs following the host´s immunological weakness. Restrictions in treatment of fungal disease such as drug resistance and side-effects of drugs have led researchers to new drugs, especially herbal medicines. The objective of this study was to compare the antifangal effects of methanolic extract of Rhus Coriaria and nystatin on candida albicans strains.Materials and Methods: the specimens were taken from oral mucus of kids with different kinds of cancers who underwent chemotherapy and were cultured in malt extract agar medium. Then methanolic extract from Rhus Coriaria were prepared by maceration method and antifungal effect of extract of this herb was evaluated on strains of Candida albicans through broth microdilution test. MIC was determined after 24 hours of culture.Results: results showed that the methanolic extract of Rhus coriaria did not have the ability to inhibit strains of Candida albicans and at concentration of at least 512 mg/L, it can exert its inhibitory effect, while the effective range of Nystatin was 0.016 to 0.125 mg/L. In addition results of MIC, MIC50, MIC90 and Gmean revealed lower values which demonstrate the higher inhibitory potency of this drug.Conclusion: methanolic extract of sumac have inhibitory effect on Candida albicans at high concentration and could be used in traditional medicine more broadly against Candida albicans yeast. However the effect was weaker than that of Nystatin.Key words: Sumac, Candida albicans, Methanolic Extract, Nystatin." @default.
- W3012988067 created "2020-04-03" @default.
- W3012988067 creator A5062811279 @default.
- W3012988067 date "2019-09-01" @default.
- W3012988067 modified "2023-09-27" @default.
- W3012988067 title "In vitro Comparison of antifungal effects of Sumac extract and Nystatin on Candida albicans" @default.
- W3012988067 hasPublicationYear "2019" @default.
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