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• W3013046175 abstract "Zika Virus (ZIKV) is transmitted primarily by Aedes aegypti mosquitoes, resulting in asymptomatic infection, or acute illness with a fever and headache, or neurological complications, such as Guillain-Barre syndrome or fetal microcephaly. Previously, we determined that AgBR1, a mosquito salivary protein, induces inflammatory responses at the bite site, and that passive immunization with AgBR1 antiserum influences mosquito-transmitted ZIKV infection. Here, we show that the active immunization of mice with AgBR1 adjuvanted with aluminum hydroxide delays lethal mosquito-borne ZIKV infection, suggesting that AgBR1 may be used as part of a vaccine to combat ZIKV." @default.
• W3013046175 created "2020-04-03" @default.
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• W3013046175 date "2020-03-25" @default.
• W3013046175 modified "2023-10-12" @default.
• W3013046175 title "Vaccination with Aedes aegypti AgBR1 Delays Lethal Mosquito-Borne Zika Virus Infection in Mice" @default.
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• W3013046175 doi "https://doi.org/10.3390/vaccines8020145" @default.
• W3013046175 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7348886" @default.
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