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• W3013121256 abstract "Abstract Gadolinium metallofullerene (Gd@C 82 ), a novel star carbonaceous material, has allured considerable attention due to its attractive properties. Increasing evidence exhibits that functionalized Gd@C 82 nanomaterials have great potential in various biomedical applications. Except for the earliest bioapplication as the next‐generation of magnetic resonance imaging contrast agent, Gd@C 82 nanomaterials perform excellent anti‐cancer activities. Functionalized Gd@C 82 nanomaterials could inhibit tumor growth by suppressing tumor angiogenesis, cutting off the existing tumor vasculature under radiofrequency irradiation or modulating immune cells. In addition, Gd@C 82 nanomaterials could be adjuvant agents to lower the toxicity of chemotherapeutic drugs and alleviate drug resistance. In particular, Gd@C 82 nanomaterials are demonstrated to regulate glucose and lipid metabolism, presenting superior anti‐type 2 diabetes mellitus effects. With no detectable toxicity and pleiotropic biological effects, Gd@C 82 nanomaterials could be promising biomedical platforms in the future." @default.
• W3013121256 created "2020-04-03" @default.
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• W3013121256 date "2020-03-01" @default.
• W3013121256 modified "2023-10-05" @default.
• W3013121256 title "The potential biomedical platforms based on the functionalized Gd@C₈₂ nanomaterials" @default.
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• W3013121256 doi "https://doi.org/10.1002/viw2.7" @default.
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