Matches in SemOpenAlex for { <https://semopenalex.org/work/W3013296593> ?p ?o ?g. }
- W3013296593 endingPage "e000357" @default.
- W3013296593 startingPage "e000357" @default.
- W3013296593 abstract "Objective To examine the effects of belimumab initiation on healthcare resource utilisation (HCRU) and costs in SLE. Methods This retrospective observational cohort study used healthcare administrative claims data from the IBM MarketScan Commercial Claims and Encounters Database to identify patients with SLE billing codes who received ≥1 intravenous belimumab infusion between March 2011 and December 2015. The first belimumab administration was the ‘index date’. During the 6-month postindex period, nine belimumab infusions were recommended: three during the initiation period and six during the maintenance period. HCRU and cost data for inpatient admissions, emergency department visits, physician office visits, hospital-based outpatient visits, laboratory services, other outpatient services and outpatient pharmacy prescriptions were compared in the 6-month pre/postindex periods. Results Of the 1879 patients with SLE included, 43% received ≥3 intravenous initiation administrations. An average of 5.3 (SD: 2.4) of the nine recommended belimumab administrations were received within 6 months. In the 6-month preindex versus postindex periods, significant reductions were noted for inpatient hospitalisations (18% vs 9%, p<0.001; mean visits: 0.3 vs 0.14, p<0.001) and emergency department visits (40% vs 24%, p<0.001; mean visits; 3.53 vs 1.96, p<0.001). Mean total costs were higher in the 6-month postindex versus preindex period ($41 426 vs $29 270; p<0.001). Conclusions In this study of real-world intravenous belimumab for SLE, adherence to recommended infusion schedules was low. Outpatient healthcare and associated costs were higher in the 6 months after belimumab was initiated, although inpatient costs were lower. Reasons for non-adherence with belimumab and implications should be investigated." @default.
- W3013296593 created "2020-04-03" @default.
- W3013296593 creator A5010362958 @default.
- W3013296593 creator A5023104531 @default.
- W3013296593 creator A5024277355 @default.
- W3013296593 creator A5064604780 @default.
- W3013296593 creator A5067531937 @default.
- W3013296593 creator A5071090995 @default.
- W3013296593 creator A5077494238 @default.
- W3013296593 creator A5081884902 @default.
- W3013296593 creator A5086351530 @default.
- W3013296593 date "2020-03-01" @default.
- W3013296593 modified "2023-10-16" @default.
- W3013296593 title "Real-world treatment patterns, healthcare resource utilisation and costs in patients with systemic lupus erythematosus treated with belimumab: a retrospective analysis of claims data in the USA" @default.
- W3013296593 cites W1518483167 @default.
- W3013296593 cites W1898467809 @default.
- W3013296593 cites W2000445173 @default.
- W3013296593 cites W2004227465 @default.
- W3013296593 cites W2018760896 @default.
- W3013296593 cites W2042719511 @default.
- W3013296593 cites W2052801802 @default.
- W3013296593 cites W2053709659 @default.
- W3013296593 cites W2060208115 @default.
- W3013296593 cites W2064999867 @default.
- W3013296593 cites W2071937222 @default.
- W3013296593 cites W2096286605 @default.
- W3013296593 cites W2104867619 @default.
- W3013296593 cites W2107216509 @default.
- W3013296593 cites W2108905161 @default.
- W3013296593 cites W2111511771 @default.
- W3013296593 cites W2129931607 @default.
- W3013296593 cites W2131457901 @default.
- W3013296593 cites W2136149088 @default.
- W3013296593 cites W2138217467 @default.
- W3013296593 cites W2151986880 @default.
- W3013296593 cites W2154001276 @default.
- W3013296593 cites W2255119417 @default.
- W3013296593 cites W2338584698 @default.
- W3013296593 cites W2547795930 @default.
- W3013296593 cites W2549420521 @default.
- W3013296593 cites W2575131381 @default.
- W3013296593 cites W2593714154 @default.
- W3013296593 cites W2756377741 @default.
- W3013296593 cites W2775607224 @default.
- W3013296593 cites W2782542157 @default.
- W3013296593 cites W2783899083 @default.
- W3013296593 cites W2789623741 @default.
- W3013296593 cites W2791812865 @default.
- W3013296593 cites W2883386662 @default.
- W3013296593 cites W2884398163 @default.
- W3013296593 cites W2885717820 @default.
- W3013296593 cites W2897481945 @default.
- W3013296593 cites W2898166905 @default.
- W3013296593 doi "https://doi.org/10.1136/lupus-2019-000357" @default.
- W3013296593 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7174061" @default.
- W3013296593 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32341790" @default.
- W3013296593 hasPublicationYear "2020" @default.
- W3013296593 type Work @default.
- W3013296593 sameAs 3013296593 @default.
- W3013296593 citedByCount "13" @default.
- W3013296593 countsByYear W30132965932020 @default.
- W3013296593 countsByYear W30132965932021 @default.
- W3013296593 countsByYear W30132965932022 @default.
- W3013296593 countsByYear W30132965932023 @default.
- W3013296593 crossrefType "journal-article" @default.
- W3013296593 hasAuthorship W3013296593A5010362958 @default.
- W3013296593 hasAuthorship W3013296593A5023104531 @default.
- W3013296593 hasAuthorship W3013296593A5024277355 @default.
- W3013296593 hasAuthorship W3013296593A5064604780 @default.
- W3013296593 hasAuthorship W3013296593A5067531937 @default.
- W3013296593 hasAuthorship W3013296593A5071090995 @default.
- W3013296593 hasAuthorship W3013296593A5077494238 @default.
- W3013296593 hasAuthorship W3013296593A5081884902 @default.
- W3013296593 hasAuthorship W3013296593A5086351530 @default.
- W3013296593 hasBestOaLocation W30132965931 @default.
- W3013296593 hasConcept C104863432 @default.
- W3013296593 hasConcept C126322002 @default.
- W3013296593 hasConcept C159110408 @default.
- W3013296593 hasConcept C159654299 @default.
- W3013296593 hasConcept C160735492 @default.
- W3013296593 hasConcept C162324750 @default.
- W3013296593 hasConcept C167135981 @default.
- W3013296593 hasConcept C170286685 @default.
- W3013296593 hasConcept C194828623 @default.
- W3013296593 hasConcept C203014093 @default.
- W3013296593 hasConcept C2426938 @default.
- W3013296593 hasConcept C2778453870 @default.
- W3013296593 hasConcept C2779457091 @default.
- W3013296593 hasConcept C2780724011 @default.
- W3013296593 hasConcept C2781205201 @default.
- W3013296593 hasConcept C50522688 @default.
- W3013296593 hasConcept C512399662 @default.
- W3013296593 hasConcept C71924100 @default.
- W3013296593 hasConcept C98274493 @default.
- W3013296593 hasConceptScore W3013296593C104863432 @default.
- W3013296593 hasConceptScore W3013296593C126322002 @default.
- W3013296593 hasConceptScore W3013296593C159110408 @default.
- W3013296593 hasConceptScore W3013296593C159654299 @default.