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- W3013535722 abstract "Background Treatment induced neuropathy of diabetes (TIND) is an iatrogenic painful sensory and autonomic neuropathy. Although the prevalence is not known, it is seen in up to 10% of tertiary cases referred for evaluation of diabetic neuropathy. Evidence TIND is associated with a decrease in the glycosylated hemoglobin A1C in individuals with longstanding hyperglycemia. TIND is more common in individuals with type 1 diabetes, but can occur in anyone with diabetes through the use of insulin, oral hypoglycemic medications or diet control. There is an acute or subacute onset of neuropathy that is linked to the change in glucose control. Although the primary clinical manifestation is neuropathic pain there is a concurrent development of autonomic dysfunction, retinopathy and nephropathy. Conclusion TIND is more common than previously suspected. The number of cases reported over the past 10 years is much greater than historical literature predicted. Increased attention to target glucose control as a physician metric could suggest a possible explanation for the increased in TIND cases reported in recent years. At present, supportive care is the only recommended treatment. Future research is necessary to define the underlying mechanism, prevent development and to guide treatment recommendations." @default.
- W3013535722 created "2020-04-03" @default.
- W3013535722 creator A5080318795 @default.
- W3013535722 date "2020-07-01" @default.
- W3013535722 modified "2023-10-03" @default.
- W3013535722 title "Treatment induced neuropathy of diabetes" @default.
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- W3013535722 doi "https://doi.org/10.1016/j.autneu.2020.102668" @default.
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