Matches in SemOpenAlex for { <https://semopenalex.org/work/W3013609568> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3013609568 abstract "Background Patients with demyelination may manifest features of autoimmune rheumatic diseases. We evaluated patients presenting with a demyelinating syndrome and clinical or autoantibody evidence for an underlying connective tissue disease (CTD). Methods Patients with clinical and/or imaging evidence of demyelination referred to a rheumatology unit. Diagnoses of multiple sclerosis (MS) and systemic lupus erythematosus (SLE) were made according to McDonald and SLICC classification criteria, respectively. Patients with features of CTD not fulfilling criteria for a specific disease were labelled as demyelination with autoimmune features (DAF). Demographics, clinical/serological/imaging data and treatments were recorded at every visit, following multidisciplinary evaluation (neurology, rheumatology, neuroimaging). Results Sixty-five patients (n=65) were included in the study [93.8% female, mean (SD) age at first demyelinating episode 37.3 (11.8) and median (IQR) duration to last follow-up 4 (7) years]. Rheumatologic clinical manifestations and autoantibodies of all patients are summarized in table 1. Fifty-two patients had lesions in the brain (80%), 32 in the spinal cord (49.2%) and 5 in the brainstem (7.7%), while 17 developed optic neuritis (26.2%). Among the 65 patients, at last follow-up, 32 patients (49.2%) had fulfilled diagnostic criteria for MS with 11 patients (34.4)) diagnosed as overlap between SLE and MS and 16 patients (50%) had CTD features not fulfilling criteria for any known CTD. Of patients with demyelinating syndrome not fulfilling criteria for MS (n=33), 7 patients (21.2%) had SLE while 22 patients (66.7%) were classified as DAF. Most common features of DAF patients were ANA, arthritis and mucocutaneous features of SLE. Conclusions Among patients with demyelination and features of CTD a significant number of patients do not fulfil criteria for either MS or SLE. These patients exhibit lupus-like autoimmune features and may represent a distinct group of patients." @default.
- W3013609568 created "2020-04-03" @default.
- W3013609568 creator A5003622109 @default.
- W3013609568 creator A5009369726 @default.
- W3013609568 creator A5020562135 @default.
- W3013609568 creator A5023351538 @default.
- W3013609568 creator A5025805658 @default.
- W3013609568 creator A5029760845 @default.
- W3013609568 creator A5037662290 @default.
- W3013609568 creator A5065825596 @default.
- W3013609568 creator A5067637059 @default.
- W3013609568 creator A5073207822 @default.
- W3013609568 date "2020-03-01" @default.
- W3013609568 modified "2023-09-27" @default.
- W3013609568 title "P151 Demyelination with autoimmune features (DAF) – results from the attikon cohort" @default.
- W3013609568 doi "https://doi.org/10.1136/lupus-2020-eurolupus.194" @default.
- W3013609568 hasPublicationYear "2020" @default.
- W3013609568 type Work @default.
- W3013609568 sameAs 3013609568 @default.
- W3013609568 citedByCount "0" @default.
- W3013609568 crossrefType "proceedings-article" @default.
- W3013609568 hasAuthorship W3013609568A5003622109 @default.
- W3013609568 hasAuthorship W3013609568A5009369726 @default.
- W3013609568 hasAuthorship W3013609568A5020562135 @default.
- W3013609568 hasAuthorship W3013609568A5023351538 @default.
- W3013609568 hasAuthorship W3013609568A5025805658 @default.
- W3013609568 hasAuthorship W3013609568A5029760845 @default.
- W3013609568 hasAuthorship W3013609568A5037662290 @default.
- W3013609568 hasAuthorship W3013609568A5065825596 @default.
- W3013609568 hasAuthorship W3013609568A5067637059 @default.
- W3013609568 hasAuthorship W3013609568A5073207822 @default.
- W3013609568 hasBestOaLocation W30136095681 @default.
- W3013609568 hasConcept C111368507 @default.
- W3013609568 hasConcept C118552586 @default.
- W3013609568 hasConcept C125533998 @default.
- W3013609568 hasConcept C126322002 @default.
- W3013609568 hasConcept C127313418 @default.
- W3013609568 hasConcept C159654299 @default.
- W3013609568 hasConcept C163764329 @default.
- W3013609568 hasConcept C16568411 @default.
- W3013609568 hasConcept C187382586 @default.
- W3013609568 hasConcept C198451711 @default.
- W3013609568 hasConcept C203014093 @default.
- W3013609568 hasConcept C2775941666 @default.
- W3013609568 hasConcept C2776670291 @default.
- W3013609568 hasConcept C2777185649 @default.
- W3013609568 hasConcept C2778962941 @default.
- W3013609568 hasConcept C2779075594 @default.
- W3013609568 hasConcept C2779134260 @default.
- W3013609568 hasConcept C2780640218 @default.
- W3013609568 hasConcept C2781028063 @default.
- W3013609568 hasConcept C2781137167 @default.
- W3013609568 hasConcept C71924100 @default.
- W3013609568 hasConcept C72563966 @default.
- W3013609568 hasConceptScore W3013609568C111368507 @default.
- W3013609568 hasConceptScore W3013609568C118552586 @default.
- W3013609568 hasConceptScore W3013609568C125533998 @default.
- W3013609568 hasConceptScore W3013609568C126322002 @default.
- W3013609568 hasConceptScore W3013609568C127313418 @default.
- W3013609568 hasConceptScore W3013609568C159654299 @default.
- W3013609568 hasConceptScore W3013609568C163764329 @default.
- W3013609568 hasConceptScore W3013609568C16568411 @default.
- W3013609568 hasConceptScore W3013609568C187382586 @default.
- W3013609568 hasConceptScore W3013609568C198451711 @default.
- W3013609568 hasConceptScore W3013609568C203014093 @default.
- W3013609568 hasConceptScore W3013609568C2775941666 @default.
- W3013609568 hasConceptScore W3013609568C2776670291 @default.
- W3013609568 hasConceptScore W3013609568C2777185649 @default.
- W3013609568 hasConceptScore W3013609568C2778962941 @default.
- W3013609568 hasConceptScore W3013609568C2779075594 @default.
- W3013609568 hasConceptScore W3013609568C2779134260 @default.
- W3013609568 hasConceptScore W3013609568C2780640218 @default.
- W3013609568 hasConceptScore W3013609568C2781028063 @default.
- W3013609568 hasConceptScore W3013609568C2781137167 @default.
- W3013609568 hasConceptScore W3013609568C71924100 @default.
- W3013609568 hasConceptScore W3013609568C72563966 @default.
- W3013609568 hasLocation W30136095681 @default.
- W3013609568 hasOpenAccess W3013609568 @default.
- W3013609568 hasPrimaryLocation W30136095681 @default.
- W3013609568 hasRelatedWork W12443314 @default.
- W3013609568 hasRelatedWork W13695726 @default.
- W3013609568 hasRelatedWork W15039402 @default.
- W3013609568 hasRelatedWork W15084687 @default.
- W3013609568 hasRelatedWork W15147048 @default.
- W3013609568 hasRelatedWork W17808429 @default.
- W3013609568 hasRelatedWork W19024072 @default.
- W3013609568 hasRelatedWork W2222768 @default.
- W3013609568 hasRelatedWork W2683960 @default.
- W3013609568 hasRelatedWork W1815238 @default.
- W3013609568 isParatext "false" @default.
- W3013609568 isRetracted "false" @default.
- W3013609568 magId "3013609568" @default.
- W3013609568 workType "article" @default.