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• W3013623973 abstract "The cholinergic anti-inflammatory pathway (CAP) is a neuro-immunomodulatory pathway,in which acetylcholine (ACh) released by the interaction of vagal nerves with α7 nicotinic acetylcholine receptor (α7nAChR),which prevents the synthesis and release of pro-inflammatory cytokines and ultimately regulates the local or systemic inflammatory response in a feedback manner. It has been shown that there are many possible effective treatments for sepsis, including vagus nerve stimulation by physical therapy, drugs such as acetylcholine receptor agonist and ultrasound therapy.胆碱能抗炎通路是一种神经-免疫调节通路。迷走神经刺激释放的乙酰胆碱与α7烟碱型乙酰胆碱受体的相互作用可阻止促炎细胞因子的合成和释放，最终反馈地调节局部或全身性炎症反应。物理方法刺激迷走神经、药物(如乙酰胆碱受体激动剂)和超声的应用等均可通过胆碱能抗炎通路有效抑制脓毒症的发展。." @default.
• W3013623973 created "2020-04-03" @default.
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• W3013623973 date "2020-01-28" @default.
• W3013623973 modified "2023-09-26" @default.
• W3013623973 title "Cholinergic anti-inflammatory pathway and its role in treatment of sepsis." @default.
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• W3013623973 doi "https://doi.org/10.11817/j.issn.1672-7347.2020.180651" @default.
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