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• W3013668650 abstract "Contezolid (MRX-I), a new oxazolidinone, is an antibiotic in development for treating complicated skin and soft tissue infections caused by resistant Gram-positive bacteria. This was a thorough QT study conducted in 52 healthy subjects who were administered oral contezolid at a therapeutic (800 mg) dose, a supratherapeutic (1,600 mg) dose, placebo, and oral moxifloxacin at 400 mg in four separate treatment periods. The pharmacokinetic profile of contezolid was also evaluated." @default.
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• W3013668650 date "2020-05-21" @default.
• W3013668650 modified "2023-10-12" @default.
• W3013668650 title "Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers" @default.
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• W3013668650 doi "https://doi.org/10.1128/aac.02158-19" @default.
• W3013668650 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7269508" @default.
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