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- W3013702502 endingPage "2000055" @default.
- W3013702502 startingPage "2000055" @default.
- W3013702502 abstract "Tailoring personalized cancer nanomedicines demands detailed understanding of the tumor microenvironment. In recent years, smart upconversion nanoparticles with the ability to exploit the unique characteristics of the tumor microenvironment for precise targeting have been designed. To activate upconversion nanoparticles, various bio-physicochemical characteristics of the tumor microenvironment, namely, acidic pH, redox reactants, and hypoxia, are exploited. Stimuli-responsive upconversion nanoparticles also utilize the excessive presence of adenosine triphosphate (ATP), riboflavin, and Zn2+ in tumors. An overview of the design of stimulus-responsive upconversion nanoparticles that precisely target and respond to tumors via targeting the tumor microenvironment and intracellular signals is provided. Detailed understanding of the tumor microenvironment and the personalized design of upconversion nanoparticles will result in more effective clinical translation." @default.
- W3013702502 created "2020-04-03" @default.
- W3013702502 creator A5036201261 @default.
- W3013702502 creator A5036476515 @default.
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- W3013702502 creator A5069459323 @default.
- W3013702502 creator A5073108451 @default.
- W3013702502 creator A5078707856 @default.
- W3013702502 date "2020-03-29" @default.
- W3013702502 modified "2023-10-10" @default.
- W3013702502 title "Designing Stimuli‐Responsive Upconversion Nanoparticles that Exploit the Tumor Microenvironment" @default.
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