Matches in SemOpenAlex for { <https://semopenalex.org/work/W3013735880> ?p ?o ?g. }
- W3013735880 endingPage "103740" @default.
- W3013735880 startingPage "103740" @default.
- W3013735880 abstract "Abstract When the head is rotated rapidly, the movement of the brain lags that of the skull. Intracranial contents between the brain and skull include meninges, cerebrospinal fluid (CSF), and cerebral vasculature. Among the cerebral vasculature in this space are the parasagittal bridging veins (BVs), which drain blood from the brain into the superior sagittal sinus (SSS), which is housed within the falx cerebri, adhered to the inner surface of the skull. Differential motion between the brain and skull that may occur during a traumatic event is thought to stretch BVs, causing damage and producing extra-axial hemorrhage (EAH). Finite element (FE) modeling is a technique often used to aid in the understanding and prediction of traumatic brain injury (TBI), and estimation of tissue deformation during traumatic events provides insight into kinematic injury thresholds. Using a FE model of the newborn porcine head with neonatal porcine brain and BV properties, single and cyclic rapid head rotations without impact were simulated. Measured BV failure properties were used to predict BV rupture. By comparing simulation outputs to observations of EAH in a development group of in vivo studies of rapid non-impact head rotations in the piglet, it was determined that failure of 16.7% of BV elements was associated with a 50% risk of EAH, and showed in a separate validation group that this threshold predicted the occurrence of EAH with 100% sensitivity and 100% specificity for single rapid non-impact rotations. This threshold for failed BV elements performed with 90% overall correct prediction in simulations of cyclic rotational head injuries. A 50% risk of EAH was associated with head angular velocities of 94.74 rad/s and angular accelerations of 29.60 krad/s2 in the newborn piglet. Future studies may build on these findings for BV failure in the piglet to develop predictive models for BV failure in human infants." @default.
- W3013735880 created "2020-04-03" @default.
- W3013735880 creator A5005906505 @default.
- W3013735880 creator A5007837816 @default.
- W3013735880 creator A5045558651 @default.
- W3013735880 creator A5060021761 @default.
- W3013735880 date "2020-06-01" @default.
- W3013735880 modified "2023-10-17" @default.
- W3013735880 title "Predictions of neonatal porcine bridging vein rupture and extra-axial hemorrhage during rapid head rotations" @default.
- W3013735880 cites W1843389589 @default.
- W3013735880 cites W1963892608 @default.
- W3013735880 cites W1979322643 @default.
- W3013735880 cites W1985664310 @default.
- W3013735880 cites W2006799916 @default.
- W3013735880 cites W2019613848 @default.
- W3013735880 cites W2020305188 @default.
- W3013735880 cites W2033898064 @default.
- W3013735880 cites W2055574236 @default.
- W3013735880 cites W2076922837 @default.
- W3013735880 cites W2078303558 @default.
- W3013735880 cites W2085582158 @default.
- W3013735880 cites W2086426203 @default.
- W3013735880 cites W2088974587 @default.
- W3013735880 cites W2090372763 @default.
- W3013735880 cites W2093259250 @default.
- W3013735880 cites W2126904329 @default.
- W3013735880 cites W2176428774 @default.
- W3013735880 cites W2549675927 @default.
- W3013735880 cites W2607352135 @default.
- W3013735880 cites W2791573553 @default.
- W3013735880 cites W2889178100 @default.
- W3013735880 cites W2891312953 @default.
- W3013735880 cites W2914501650 @default.
- W3013735880 cites W2919990205 @default.
- W3013735880 cites W2993414300 @default.
- W3013735880 cites W2113936837 @default.
- W3013735880 doi "https://doi.org/10.1016/j.jmbbm.2020.103740" @default.
- W3013735880 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7228785" @default.
- W3013735880 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32250951" @default.
- W3013735880 hasPublicationYear "2020" @default.
- W3013735880 type Work @default.
- W3013735880 sameAs 3013735880 @default.
- W3013735880 citedByCount "4" @default.
- W3013735880 countsByYear W30137358802021 @default.
- W3013735880 countsByYear W30137358802023 @default.
- W3013735880 crossrefType "journal-article" @default.
- W3013735880 hasAuthorship W3013735880A5005906505 @default.
- W3013735880 hasAuthorship W3013735880A5007837816 @default.
- W3013735880 hasAuthorship W3013735880A5045558651 @default.
- W3013735880 hasAuthorship W3013735880A5060021761 @default.
- W3013735880 hasBestOaLocation W30137358801 @default.
- W3013735880 hasConcept C105702510 @default.
- W3013735880 hasConcept C114793014 @default.
- W3013735880 hasConcept C127313418 @default.
- W3013735880 hasConcept C127413603 @default.
- W3013735880 hasConcept C136229726 @default.
- W3013735880 hasConcept C174348530 @default.
- W3013735880 hasConcept C192562407 @default.
- W3013735880 hasConcept C2780312720 @default.
- W3013735880 hasConcept C29694066 @default.
- W3013735880 hasConcept C31258907 @default.
- W3013735880 hasConcept C41008148 @default.
- W3013735880 hasConcept C66938386 @default.
- W3013735880 hasConcept C71924100 @default.
- W3013735880 hasConceptScore W3013735880C105702510 @default.
- W3013735880 hasConceptScore W3013735880C114793014 @default.
- W3013735880 hasConceptScore W3013735880C127313418 @default.
- W3013735880 hasConceptScore W3013735880C127413603 @default.
- W3013735880 hasConceptScore W3013735880C136229726 @default.
- W3013735880 hasConceptScore W3013735880C174348530 @default.
- W3013735880 hasConceptScore W3013735880C192562407 @default.
- W3013735880 hasConceptScore W3013735880C2780312720 @default.
- W3013735880 hasConceptScore W3013735880C29694066 @default.
- W3013735880 hasConceptScore W3013735880C31258907 @default.
- W3013735880 hasConceptScore W3013735880C41008148 @default.
- W3013735880 hasConceptScore W3013735880C66938386 @default.
- W3013735880 hasConceptScore W3013735880C71924100 @default.
- W3013735880 hasFunder F4320306230 @default.
- W3013735880 hasFunder F4320310224 @default.
- W3013735880 hasFunder F4320332161 @default.
- W3013735880 hasLocation W30137358801 @default.
- W3013735880 hasLocation W30137358802 @default.
- W3013735880 hasOpenAccess W3013735880 @default.
- W3013735880 hasPrimaryLocation W30137358801 @default.
- W3013735880 hasRelatedWork W1987392569 @default.
- W3013735880 hasRelatedWork W2059012321 @default.
- W3013735880 hasRelatedWork W2101112389 @default.
- W3013735880 hasRelatedWork W2128244667 @default.
- W3013735880 hasRelatedWork W2513791271 @default.
- W3013735880 hasRelatedWork W2899084033 @default.
- W3013735880 hasRelatedWork W2982110096 @default.
- W3013735880 hasRelatedWork W4233794016 @default.
- W3013735880 hasRelatedWork W4237448657 @default.
- W3013735880 hasRelatedWork W4248777835 @default.
- W3013735880 hasVolume "106" @default.
- W3013735880 isParatext "false" @default.
- W3013735880 isRetracted "false" @default.
- W3013735880 magId "3013735880" @default.