FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3013778595> ?p ?o ?g. }

• W3013778595 abstract "Abstract Molecular analysis techniques such as gene expression analysis and proteomics have contributed greatly to our understanding of cancer heterogeneity. In prior studies, gene expression analysis was shown to stratify patient outcome on the basis of tumor-microenvironment associated genes. A specific gene expression profile, referred to as ECM3 (Extracellular Matrix Cluster 3), indicated poorer survival in patients with grade III tumors. In this work, we aimed to visualize the downstream effects of this gene expression profile onto the tissue, thus providing a spatial context to altered gene expression profiles. Using infrared spectroscopic imaging, we identified spectral patterns specific to the ECM3 gene expression profile, achieving a high spectral classification performance of 0.87 as measured by the area under the curve of the receiver operating characteristic curve. On a patient level, we correctly identified 20 out of 22 ECM3 group patients and 19 out of 20 non-ECM3 group patients by using this spectroscopic imaging-based classifier. By comparing pixels that were identified as ECM3 or non-ECM3 with H&E and IHC images, we were also able to observe an association between tissue morphology and the gene expression clusters, showing the ability of our method to capture broad outcome associated features from infrared images." @default.
• W3013778595 created "2020-04-03" @default.
• W3013778595 creator A5016473783 @default.
• W3013778595 creator A5020820383 @default.
• W3013778595 creator A5023245938 @default.
• W3013778595 creator A5032157470 @default.
• W3013778595 creator A5049119014 @default.
• W3013778595 creator A5077890463 @default.
• W3013778595 creator A5083469846 @default.
• W3013778595 date "2020-03-25" @default.
• W3013778595 modified "2023-10-18" @default.
• W3013778595 title "Infrared Spectroscopic Imaging Visualizes a Prognostic Extracellular Matrix-Related Signature in Breast Cancer" @default.
• W3013778595 cites W1855871243 @default.
• W3013778595 cites W1967400010 @default.
• W3013778595 cites W1976790006 @default.
• W3013778595 cites W1989360915 @default.
• W3013778595 cites W1989773587 @default.
• W3013778595 cites W2006103332 @default.
• W3013778595 cites W2010356685 @default.
• W3013778595 cites W2011055829 @default.
• W3013778595 cites W2014446724 @default.
• W3013778595 cites W2019155872 @default.
• W3013778595 cites W2024971501 @default.
• W3013778595 cites W2033278321 @default.
• W3013778595 cites W2035244841 @default.
• W3013778595 cites W2047287346 @default.
• W3013778595 cites W2055644700 @default.
• W3013778595 cites W2060719207 @default.
• W3013778595 cites W2061931258 @default.
• W3013778595 cites W2077715347 @default.
• W3013778595 cites W2082225160 @default.
• W3013778595 cites W2090086153 @default.
• W3013778595 cites W2110909984 @default.
• W3013778595 cites W2119106121 @default.
• W3013778595 cites W2132897003 @default.
• W3013778595 cites W2141871922 @default.
• W3013778595 cites W2156934935 @default.
• W3013778595 cites W2177616800 @default.
• W3013778595 cites W2280761929 @default.
• W3013778595 cites W2293200316 @default.
• W3013778595 cites W2313075337 @default.
• W3013778595 cites W2527140315 @default.
• W3013778595 cites W2782787235 @default.
• W3013778595 cites W2790128158 @default.
• W3013778595 cites W2790986122 @default.
• W3013778595 cites W2796610682 @default.
• W3013778595 cites W2805890045 @default.
• W3013778595 cites W2808972377 @default.
• W3013778595 cites W2894588644 @default.
• W3013778595 cites W2900519915 @default.
• W3013778595 cites W2954442892 @default.
• W3013778595 cites W4250530726 @default.
• W3013778595 doi "https://doi.org/10.1038/s41598-020-62403-2" @default.
• W3013778595 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7096505" @default.
• W3013778595 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32214177" @default.
• W3013778595 hasPublicationYear "2020" @default.
• W3013778595 type Work @default.
• W3013778595 sameAs 3013778595 @default.
• W3013778595 citedByCount "5" @default.
• W3013778595 countsByYear W30137785952020 @default.
• W3013778595 countsByYear W30137785952021 @default.
• W3013778595 countsByYear W30137785952022 @default.
• W3013778595 countsByYear W30137785952023 @default.
• W3013778595 crossrefType "journal-article" @default.
• W3013778595 hasAuthorship W3013778595A5016473783 @default.
• W3013778595 hasAuthorship W3013778595A5020820383 @default.
• W3013778595 hasAuthorship W3013778595A5023245938 @default.
• W3013778595 hasAuthorship W3013778595A5032157470 @default.
• W3013778595 hasAuthorship W3013778595A5049119014 @default.
• W3013778595 hasAuthorship W3013778595A5077890463 @default.
• W3013778595 hasAuthorship W3013778595A5083469846 @default.
• W3013778595 hasBestOaLocation W30137785951 @default.
• W3013778595 hasConcept C104317684 @default.
• W3013778595 hasConcept C121608353 @default.
• W3013778595 hasConcept C126322002 @default.
• W3013778595 hasConcept C142724271 @default.
• W3013778595 hasConcept C150194340 @default.
• W3013778595 hasConcept C151730666 @default.
• W3013778595 hasConcept C18431079 @default.
• W3013778595 hasConcept C189165786 @default.
• W3013778595 hasConcept C2779343474 @default.
• W3013778595 hasConcept C502942594 @default.
• W3013778595 hasConcept C530470458 @default.
• W3013778595 hasConcept C54355233 @default.
• W3013778595 hasConcept C58471807 @default.
• W3013778595 hasConcept C60644358 @default.
• W3013778595 hasConcept C70721500 @default.
• W3013778595 hasConcept C71924100 @default.
• W3013778595 hasConcept C86803240 @default.
• W3013778595 hasConceptScore W3013778595C104317684 @default.
• W3013778595 hasConceptScore W3013778595C121608353 @default.
• W3013778595 hasConceptScore W3013778595C126322002 @default.
• W3013778595 hasConceptScore W3013778595C142724271 @default.
• W3013778595 hasConceptScore W3013778595C150194340 @default.
• W3013778595 hasConceptScore W3013778595C151730666 @default.
• W3013778595 hasConceptScore W3013778595C18431079 @default.
• W3013778595 hasConceptScore W3013778595C189165786 @default.
• W3013778595 hasConceptScore W3013778595C2779343474 @default.
• W3013778595 hasConceptScore W3013778595C502942594 @default.
• W3013778595 hasConceptScore W3013778595C530470458 @default.

• next