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- W3013898070 abstract "Triple negative breast cancers (TNBCs) are characterized by worse prognosis, higher propensity to earlier metastases, and shorter survival after recurrence compared with other breast cancer subtypes. Anthracycline- and taxane-based chemotherapy is still the mainstay of treatment in early stages, although several escalation approaches have been evaluated to improve survival outcomes. The addition of platinum salts to standard neoadjuvant chemotherapy (NACT) remains controversial due to the lack of clear survival advantage, and the use of adjuvant capecitabine represents a valid treatment option in TNBC patients with residual disease after NACT. Recently, several clinical trials showed promising results through the use of poly ADP-ribose polymerase (PARP) inhibitors and by incorporating immunotherapy with chemotherapy, enriching treatment options beyond conventional cytotoxic agents. In this review, we provided an overview on the current standard of care and a comprehensive update of the recent advances in the management of early stage TNBC and focused on the latest emerging biomarkers and their clinical application to select the best therapeutic strategy in this hard-to-treat population." @default.
- W3013898070 created "2020-04-03" @default.
- W3013898070 creator A5000459628 @default.
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- W3013898070 date "2020-03-29" @default.
- W3013898070 modified "2023-10-13" @default.
- W3013898070 title "Early Triple Negative Breast Cancer: Conventional Treatment and Emerging Therapeutic Landscapes" @default.
- W3013898070 cites W1546709038 @default.
- W3013898070 cites W1575220727 @default.
- W3013898070 cites W1940241680 @default.
- W3013898070 cites W1949237903 @default.
- W3013898070 cites W1973268287 @default.
- W3013898070 cites W2015921398 @default.
- W3013898070 cites W2044702943 @default.
- W3013898070 cites W2074952360 @default.
- W3013898070 cites W2075894019 @default.
- W3013898070 cites W2094523134 @default.
- W3013898070 cites W2095646155 @default.
- W3013898070 cites W2096745115 @default.
- W3013898070 cites W2097255042 @default.
- W3013898070 cites W2098804778 @default.
- W3013898070 cites W2103970959 @default.
- W3013898070 cites W2104638648 @default.
- W3013898070 cites W2105265201 @default.
- W3013898070 cites W2106292881 @default.
- W3013898070 cites W2114397636 @default.
- W3013898070 cites W2114505219 @default.
- W3013898070 cites W2118605519 @default.
- W3013898070 cites W2127232551 @default.
- W3013898070 cites W2127395702 @default.
- W3013898070 cites W2128458647 @default.
- W3013898070 cites W2134539328 @default.
- W3013898070 cites W2135800076 @default.
- W3013898070 cites W2136776783 @default.
- W3013898070 cites W2140654333 @default.
- W3013898070 cites W2142486051 @default.
- W3013898070 cites W2143459396 @default.
- W3013898070 cites W2144090846 @default.
- W3013898070 cites W2147415463 @default.
- W3013898070 cites W2147629880 @default.
- W3013898070 cites W2148823465 @default.
- W3013898070 cites W2152276633 @default.
- W3013898070 cites W2154888253 @default.
- W3013898070 cites W2159274850 @default.
- W3013898070 cites W2159890963 @default.
- W3013898070 cites W2162760540 @default.
- W3013898070 cites W2167926320 @default.
- W3013898070 cites W2168409298 @default.
- W3013898070 cites W2169914436 @default.
- W3013898070 cites W2171544336 @default.
- W3013898070 cites W2191558617 @default.
- W3013898070 cites W2225739806 @default.
- W3013898070 cites W2259802687 @default.
- W3013898070 cites W2287133162 @default.
- W3013898070 cites W2295085830 @default.
- W3013898070 cites W2336410037 @default.
- W3013898070 cites W2340000092 @default.
- W3013898070 cites W2340129316 @default.
- W3013898070 cites W2340735966 @default.
- W3013898070 cites W2402222196 @default.
- W3013898070 cites W2402636472 @default.
- W3013898070 cites W2430731787 @default.
- W3013898070 cites W2474664935 @default.
- W3013898070 cites W2561439167 @default.
- W3013898070 cites W2572458419 @default.
- W3013898070 cites W2585697071 @default.
- W3013898070 cites W2596164112 @default.
- W3013898070 cites W2598264809 @default.
- W3013898070 cites W2599332339 @default.
- W3013898070 cites W2606920283 @default.
- W3013898070 cites W2609430257 @default.
- W3013898070 cites W2618058692 @default.
- W3013898070 cites W2621271973 @default.
- W3013898070 cites W2745285076 @default.
- W3013898070 cites W2761452338 @default.
- W3013898070 cites W2765484031 @default.
- W3013898070 cites W2771978163 @default.
- W3013898070 cites W2774580734 @default.
- W3013898070 cites W2784030537 @default.
- W3013898070 cites W2784775153 @default.
- W3013898070 cites W2788106879 @default.
- W3013898070 cites W2792644868 @default.
- W3013898070 cites W2801956643 @default.
- W3013898070 cites W2806557019 @default.
- W3013898070 cites W2807418950 @default.
- W3013898070 cites W2807966236 @default.
- W3013898070 cites W2809205318 @default.
- W3013898070 cites W2883848636 @default.
- W3013898070 cites W2885139325 @default.
- W3013898070 cites W2886477543 @default.
- W3013898070 cites W2888149157 @default.
- W3013898070 cites W2889499644 @default.