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- W3013904011 abstract "目的探讨高危患者入院时血浆TNF-α及IL-6水平在预测急性呼吸窘迫综合征(acute respiratory distress syndrome，ARDS)发生中的作用。 方法纳入2018年6月至2019年4月本院呼吸与危重症医学中心ICU的高危患者30例，其中13例发展成为ARDS(ARDS组)，其余17例为高危组。收集入组患者的临床资料及刚入院时的血浆标本。此外，收集18例正常人血浆标本作为对照(对照组)。应用流式细胞仪，用两种因子同步检测试剂盒对样本中的TNF-α、IL-6进行定量检测。 结果ARDS组患者血浆TNF-α和IL-6水平明显高于高危组及对照组，高危组患者血浆TNF-α和IL-6水平明显高于对照组(P 0.05)。死亡组APACHE-Ⅱ评分、C反应蛋白、尿素、尿酸水平明显高于存活组，而血浆总蛋白、白蛋白及氧合指数明显低于存活组(P 结论入院时血浆中TNF-α水平与高危患者进展成为ARDS有密切关联，可作为预测ARDS发生的标志物。" @default.
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- W3013904011 date "2020-03-15" @default.
- W3013904011 modified "2023-09-26" @default.
- W3013904011 title "基于两种因子同步检测方法探讨TNF-α及IL-6在预测ARDS发生中的作用" @default.
- W3013904011 doi "https://doi.org/10.16016/j.1000-5404.201909207" @default.
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