Matches in SemOpenAlex for { <https://semopenalex.org/work/W3013942580> ?p ?o ?g. }
- W3013942580 endingPage "151" @default.
- W3013942580 startingPage "145" @default.
- W3013942580 abstract "Background and objective To evaluate the efficacy of intravitreal ziv-aflibercept (IVZ) in patients with diabetic macular edema (DME) resistant to intravitreal bevacizumab (IVB). Patients and methods This prospective study was conducted in patients with persistent DME. Patients were switched to IVZ no longer than 6 weeks after the last three consecutive monthly IVB treatments and monitored over a course of 12 weeks. Changes in best-corrected visual acuity (BCVA), central macular thickness (CMT), and macular volume on optical coherence tomography were compared. Results A total of 59 eyes (38 patients) were included. Mean BCVA improved from 0.84 to 0.71 logMAR (P = .001) after first IVZ treatment and remained significant. In a subgroup analysis, this significance was observed only in the group with baseline visual acuity of less than 20/50. Mean CMT decreased from 479 μm to 364 μm (P = .004) after the first IVZ injections and remained significant. Conclusion IVZ may be best reserved for patients with persistent DME after initial failure with bevacizumab, with less likelihood for anatomic or functional improvement in those with mild persistent DME. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:145-151.]." @default.
- W3013942580 created "2020-04-03" @default.
- W3013942580 creator A5004439899 @default.
- W3013942580 creator A5014786041 @default.
- W3013942580 creator A5015986829 @default.
- W3013942580 creator A5024597084 @default.
- W3013942580 creator A5025974785 @default.
- W3013942580 creator A5027722795 @default.
- W3013942580 creator A5029590455 @default.
- W3013942580 creator A5029725974 @default.
- W3013942580 creator A5030347575 @default.
- W3013942580 creator A5034957818 @default.
- W3013942580 creator A5058515738 @default.
- W3013942580 creator A5065255070 @default.
- W3013942580 creator A5069180488 @default.
- W3013942580 creator A5074544685 @default.
- W3013942580 creator A5078618807 @default.
- W3013942580 date "2020-03-01" @default.
- W3013942580 modified "2023-10-18" @default.
- W3013942580 title "Intravitreal Ziv-Aflibercept in Patients With Diabetic Macular Edema Refractory to Intravitreal Bevacizumab" @default.
- W3013942580 cites W1965165229 @default.
- W3013942580 cites W1976005612 @default.
- W3013942580 cites W2004117352 @default.
- W3013942580 cites W2079899325 @default.
- W3013942580 cites W2082962539 @default.
- W3013942580 cites W2090248679 @default.
- W3013942580 cites W2129525239 @default.
- W3013942580 cites W2130626478 @default.
- W3013942580 cites W2146673937 @default.
- W3013942580 cites W2216901845 @default.
- W3013942580 cites W2251610588 @default.
- W3013942580 cites W2289200040 @default.
- W3013942580 cites W2316338492 @default.
- W3013942580 cites W2320591489 @default.
- W3013942580 cites W2567410172 @default.
- W3013942580 cites W2568884027 @default.
- W3013942580 cites W2583068534 @default.
- W3013942580 cites W2612315570 @default.
- W3013942580 cites W2737460962 @default.
- W3013942580 cites W2763559849 @default.
- W3013942580 cites W2765838647 @default.
- W3013942580 cites W2789784671 @default.
- W3013942580 cites W2885896167 @default.
- W3013942580 doi "https://doi.org/10.3928/23258160-20200228-03" @default.
- W3013942580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32211904" @default.
- W3013942580 hasPublicationYear "2020" @default.
- W3013942580 type Work @default.
- W3013942580 sameAs 3013942580 @default.
- W3013942580 citedByCount "7" @default.
- W3013942580 countsByYear W30139425802020 @default.
- W3013942580 countsByYear W30139425802021 @default.
- W3013942580 countsByYear W30139425802022 @default.
- W3013942580 countsByYear W30139425802023 @default.
- W3013942580 crossrefType "journal-article" @default.
- W3013942580 hasAuthorship W3013942580A5004439899 @default.
- W3013942580 hasAuthorship W3013942580A5014786041 @default.
- W3013942580 hasAuthorship W3013942580A5015986829 @default.
- W3013942580 hasAuthorship W3013942580A5024597084 @default.
- W3013942580 hasAuthorship W3013942580A5025974785 @default.
- W3013942580 hasAuthorship W3013942580A5027722795 @default.
- W3013942580 hasAuthorship W3013942580A5029590455 @default.
- W3013942580 hasAuthorship W3013942580A5029725974 @default.
- W3013942580 hasAuthorship W3013942580A5030347575 @default.
- W3013942580 hasAuthorship W3013942580A5034957818 @default.
- W3013942580 hasAuthorship W3013942580A5058515738 @default.
- W3013942580 hasAuthorship W3013942580A5065255070 @default.
- W3013942580 hasAuthorship W3013942580A5069180488 @default.
- W3013942580 hasAuthorship W3013942580A5074544685 @default.
- W3013942580 hasAuthorship W3013942580A5078618807 @default.
- W3013942580 hasConcept C118487528 @default.
- W3013942580 hasConcept C126322002 @default.
- W3013942580 hasConcept C134018914 @default.
- W3013942580 hasConcept C142424586 @default.
- W3013942580 hasConcept C159985019 @default.
- W3013942580 hasConcept C192562407 @default.
- W3013942580 hasConcept C2776694085 @default.
- W3013942580 hasConcept C2777802072 @default.
- W3013942580 hasConcept C2778749236 @default.
- W3013942580 hasConcept C2779829184 @default.
- W3013942580 hasConcept C2781100027 @default.
- W3013942580 hasConcept C2985127711 @default.
- W3013942580 hasConcept C555293320 @default.
- W3013942580 hasConcept C71924100 @default.
- W3013942580 hasConceptScore W3013942580C118487528 @default.
- W3013942580 hasConceptScore W3013942580C126322002 @default.
- W3013942580 hasConceptScore W3013942580C134018914 @default.
- W3013942580 hasConceptScore W3013942580C142424586 @default.
- W3013942580 hasConceptScore W3013942580C159985019 @default.
- W3013942580 hasConceptScore W3013942580C192562407 @default.
- W3013942580 hasConceptScore W3013942580C2776694085 @default.
- W3013942580 hasConceptScore W3013942580C2777802072 @default.
- W3013942580 hasConceptScore W3013942580C2778749236 @default.
- W3013942580 hasConceptScore W3013942580C2779829184 @default.
- W3013942580 hasConceptScore W3013942580C2781100027 @default.
- W3013942580 hasConceptScore W3013942580C2985127711 @default.
- W3013942580 hasConceptScore W3013942580C555293320 @default.
- W3013942580 hasConceptScore W3013942580C71924100 @default.
- W3013942580 hasIssue "3" @default.