Matches in SemOpenAlex for { <https://semopenalex.org/work/W3014004114> ?p ?o ?g. }
- W3014004114 abstract "ABSTRACT Background The 2019 novel coronavirus disease (COVID-19) emerged in Wuhan, Hubei province, China, and was characterized as pandemic by the World Health Organization. Diabetes mellitus is an established risk factor for poor clinical outcomes, but the association of diabetes with the prognosis of COVID-19 have not been reported yet. Methods In this cohort study, we retrospectively reviewed 258 consecutive hospitalized COVID-19 patients with or without diabetes at the West Court of Union Hospital of Huazhong University of Science and Technology in Wuhan, China, recruited from January 29 to February 12, 2020. The cases were confirmed by real-time PCR and the demographic, clinical, laboratory, radiological, and treatment data were collected and analyzed. Prognosis was defined as hospitalization, discharged survivor and death, which was followed up until March 12, 2020. Results Of the 258 hospitalized patients (63 with diabetes) with COVID-19, the median age was 64 years (range 23-91), and 138 (53.5%) were male. No significant differences in age and sex were identified between patients with and without diabetes. Common symptoms included fever (82.2%), dry cough (67.1%), polypnea (48.1%), and fatigue (38%). Patients with diabetes had significantly higher leucocyte and neutrophil counts, and higher levels of fasting blood glucose, serum creatinine, urea nitrogen and creatine kinase isoenzyme MB at admission compared with those without diabetes. COVID-19 patients with diabetes were more likely to develop severe or critical disease condition with more complications at presentation, and had higher incidence rates of antibiotic therapy, non-invasive and invasive mechanical ventilation, and death (11.1% vs. 4.1%). Cox proportional hazard model showed that diabetes (adjusted hazard ratio [aHR]=3.64; 95% confidence interval [CI]: 1.09, 12.21) and fasting blood glucose (aHR=1.19; 95% CI: 1.08, 1.31) were associated with the fatality of COVID-19, adjusting for potential confounders. Conclusions Diabetes mellitus is associated with greater disease severity and a higher risk of mortality in patients with COVID-19. Primary and secondary prevention strategies are needed for COVID-19 patients with diabetes." @default.
- W3014004114 created "2020-04-03" @default.
- W3014004114 creator A5001923911 @default.
- W3014004114 creator A5001969147 @default.
- W3014004114 creator A5006524322 @default.
- W3014004114 creator A5016167992 @default.
- W3014004114 creator A5017826942 @default.
- W3014004114 creator A5026304465 @default.
- W3014004114 creator A5052925180 @default.
- W3014004114 creator A5053368151 @default.
- W3014004114 creator A5058738192 @default.
- W3014004114 creator A5067139711 @default.
- W3014004114 creator A5068144237 @default.
- W3014004114 creator A5076768386 @default.
- W3014004114 creator A5086664284 @default.
- W3014004114 creator A5087525232 @default.
- W3014004114 creator A5090963267 @default.
- W3014004114 date "2020-03-26" @default.
- W3014004114 modified "2023-10-10" @default.
- W3014004114 title "Comorbid Diabetes Mellitus was Associated with Poorer Prognosis in Patients with COVID-19: A Retrospective Cohort Study" @default.
- W3014004114 cites W1803784511 @default.
- W3014004114 cites W1980717583 @default.
- W3014004114 cites W2023419926 @default.
- W3014004114 cites W2029648873 @default.
- W3014004114 cites W2115491405 @default.
- W3014004114 cites W2163567504 @default.
- W3014004114 cites W2286011088 @default.
- W3014004114 cites W2432313235 @default.
- W3014004114 cites W2469586991 @default.
- W3014004114 cites W2731349674 @default.
- W3014004114 cites W2955148946 @default.
- W3014004114 cites W2974984390 @default.
- W3014004114 cites W3001118548 @default.
- W3014004114 cites W3002108456 @default.
- W3014004114 cites W3004318991 @default.
- W3014004114 cites W3006480846 @default.
- W3014004114 cites W3007814559 @default.
- W3014004114 cites W3008090866 @default.
- W3014004114 cites W3008589801 @default.
- W3014004114 cites W3023991776 @default.
- W3014004114 cites W3165656738 @default.
- W3014004114 cites W4253731276 @default.
- W3014004114 doi "https://doi.org/10.1101/2020.03.24.20042358" @default.
- W3014004114 hasPublicationYear "2020" @default.
- W3014004114 type Work @default.
- W3014004114 sameAs 3014004114 @default.
- W3014004114 citedByCount "22" @default.
- W3014004114 countsByYear W30140041142020 @default.
- W3014004114 countsByYear W30140041142021 @default.
- W3014004114 countsByYear W30140041142022 @default.
- W3014004114 countsByYear W30140041142023 @default.
- W3014004114 crossrefType "posted-content" @default.
- W3014004114 hasAuthorship W3014004114A5001923911 @default.
- W3014004114 hasAuthorship W3014004114A5001969147 @default.
- W3014004114 hasAuthorship W3014004114A5006524322 @default.
- W3014004114 hasAuthorship W3014004114A5016167992 @default.
- W3014004114 hasAuthorship W3014004114A5017826942 @default.
- W3014004114 hasAuthorship W3014004114A5026304465 @default.
- W3014004114 hasAuthorship W3014004114A5052925180 @default.
- W3014004114 hasAuthorship W3014004114A5053368151 @default.
- W3014004114 hasAuthorship W3014004114A5058738192 @default.
- W3014004114 hasAuthorship W3014004114A5067139711 @default.
- W3014004114 hasAuthorship W3014004114A5068144237 @default.
- W3014004114 hasAuthorship W3014004114A5076768386 @default.
- W3014004114 hasAuthorship W3014004114A5086664284 @default.
- W3014004114 hasAuthorship W3014004114A5087525232 @default.
- W3014004114 hasAuthorship W3014004114A5090963267 @default.
- W3014004114 hasBestOaLocation W30140041141 @default.
- W3014004114 hasConcept C120665830 @default.
- W3014004114 hasConcept C121332964 @default.
- W3014004114 hasConcept C126322002 @default.
- W3014004114 hasConcept C134018914 @default.
- W3014004114 hasConcept C167135981 @default.
- W3014004114 hasConcept C2779134260 @default.
- W3014004114 hasConcept C2780306776 @default.
- W3014004114 hasConcept C555293320 @default.
- W3014004114 hasConcept C61511704 @default.
- W3014004114 hasConcept C71924100 @default.
- W3014004114 hasConcept C72563966 @default.
- W3014004114 hasConceptScore W3014004114C120665830 @default.
- W3014004114 hasConceptScore W3014004114C121332964 @default.
- W3014004114 hasConceptScore W3014004114C126322002 @default.
- W3014004114 hasConceptScore W3014004114C134018914 @default.
- W3014004114 hasConceptScore W3014004114C167135981 @default.
- W3014004114 hasConceptScore W3014004114C2779134260 @default.
- W3014004114 hasConceptScore W3014004114C2780306776 @default.
- W3014004114 hasConceptScore W3014004114C555293320 @default.
- W3014004114 hasConceptScore W3014004114C61511704 @default.
- W3014004114 hasConceptScore W3014004114C71924100 @default.
- W3014004114 hasConceptScore W3014004114C72563966 @default.
- W3014004114 hasLocation W30140041141 @default.
- W3014004114 hasOpenAccess W3014004114 @default.
- W3014004114 hasPrimaryLocation W30140041141 @default.
- W3014004114 hasRelatedWork W1563850031 @default.
- W3014004114 hasRelatedWork W1580426574 @default.
- W3014004114 hasRelatedWork W2089620537 @default.
- W3014004114 hasRelatedWork W2275480158 @default.
- W3014004114 hasRelatedWork W2371214482 @default.
- W3014004114 hasRelatedWork W2415759662 @default.
- W3014004114 hasRelatedWork W2603773853 @default.