FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3014039480> ?p ?o ?g. }

• W3014039480 endingPage "1553" @default.
• W3014039480 startingPage "1545" @default.
• W3014039480 abstract "Although greater flavonoid intake is associated with a reduced risk of Alzheimer's disease (AD) and related dementias (ADRD), evidence relating dietary flavonoid intake to brain health based on MRI is lacking. The objective of this study was to explore the association between dietary flavonoid intake and MRI measures of brain health, including total brain tissue volume (TBV), white matter hyperintensities volume (WMHV), and hippocampal volume (HV). Eligible subjects included members of the Framingham Heart Study Offspring Cohort who were free of stroke at exam 7 and had at least 1 valid food frequency questionnaire from exams 5, 6, or 7 (n = 2086; mean age at exam 7, 60.6 y). Flavonoid intakes represented the cumulative mean of intakes across the 3 exams and were categorized based on quartiles categories of intake. TBV, WMHV, and HV were assessed at exam 7. Multiple linear regression models were used to examine the cross-sectional association between total and the 6 classes of flavonoids and the 3 aforementioned MRI measures. The mean (95% CI) of the WMHV of subjects in the highest quartile category of flavan-3-ols [0.56 (0.52, 0.61)] and flavonoid polymers [0.57 (0.52, 0.61)] intake was significantly smaller relative to that of subjects in the lowest quartile category of flavan-3-ols [0.65 (0.60, 0.71)] and flavonoid polymers [0.66 (0.60, 0.71)] after accounting for important demographic, lifestyle, and clinical factors. Inverse trend associations with WMHV were also seen for flavan-3-ols (P = 0.01) and flavonoid polymers (P = 0.01) as well as for total flavonoids (P = 0.01). TBV and HV were not associated with dietary flavonoid intake following the adjustment for potential confounders. Our results contribute to the literature on flavonoids and ADRD as they suggest that higher flavonoid intakes may affect ADRD risk in middle-aged and older adults by reducing WMHV, a marker strongly associated with ADRD." @default.
• W3014039480 created "2020-04-03" @default.
• W3014039480 creator A5017168859 @default.
• W3014039480 creator A5027262648 @default.
• W3014039480 creator A5049560816 @default.
• W3014039480 creator A5064192696 @default.
• W3014039480 creator A5071825455 @default.
• W3014039480 creator A5091165772 @default.
• W3014039480 date "2020-06-01" @default.
• W3014039480 modified "2023-10-18" @default.
• W3014039480 title "Flavonoid Intake and MRI Markers of Brain Health in the Framingham Offspring Cohort" @default.
• W3014039480 cites W1589418222 @default.
• W3014039480 cites W1795315872 @default.
• W3014039480 cites W1871783318 @default.
• W3014039480 cites W1908917727 @default.
• W3014039480 cites W1971548649 @default.
• W3014039480 cites W1987938319 @default.
• W3014039480 cites W1993391176 @default.
• W3014039480 cites W2000081470 @default.
• W3014039480 cites W2011167794 @default.
• W3014039480 cites W2017582512 @default.
• W3014039480 cites W2025578977 @default.
• W3014039480 cites W2041911313 @default.
• W3014039480 cites W2043084071 @default.
• W3014039480 cites W2054692171 @default.
• W3014039480 cites W2068629868 @default.
• W3014039480 cites W2068690916 @default.
• W3014039480 cites W2073294247 @default.
• W3014039480 cites W2089435027 @default.
• W3014039480 cites W2108909778 @default.
• W3014039480 cites W2113532044 @default.
• W3014039480 cites W2116424646 @default.
• W3014039480 cites W2120021843 @default.
• W3014039480 cites W2122477279 @default.
• W3014039480 cites W2133143931 @default.
• W3014039480 cites W2145629198 @default.
• W3014039480 cites W2156717321 @default.
• W3014039480 cites W2207219039 @default.
• W3014039480 cites W2324276018 @default.
• W3014039480 cites W2505127413 @default.
• W3014039480 cites W2520125036 @default.
• W3014039480 cites W2569405552 @default.
• W3014039480 cites W2776518474 @default.
• W3014039480 cites W2794075472 @default.
• W3014039480 cites W2797690486 @default.
• W3014039480 cites W2936365596 @default.
• W3014039480 cites W349215320 @default.
• W3014039480 doi "https://doi.org/10.1093/jn/nxaa068" @default.
• W3014039480 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7269753" @default.
• W3014039480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32211795" @default.
• W3014039480 hasPublicationYear "2020" @default.
• W3014039480 type Work @default.
• W3014039480 sameAs 3014039480 @default.
• W3014039480 citedByCount "10" @default.
• W3014039480 countsByYear W30140394802021 @default.
• W3014039480 countsByYear W30140394802022 @default.
• W3014039480 countsByYear W30140394802023 @default.
• W3014039480 crossrefType "journal-article" @default.
• W3014039480 hasAuthorship W3014039480A5017168859 @default.
• W3014039480 hasAuthorship W3014039480A5027262648 @default.
• W3014039480 hasAuthorship W3014039480A5049560816 @default.
• W3014039480 hasAuthorship W3014039480A5064192696 @default.
• W3014039480 hasAuthorship W3014039480A5071825455 @default.
• W3014039480 hasAuthorship W3014039480A5091165772 @default.
• W3014039480 hasBestOaLocation W30140394801 @default.
• W3014039480 hasConcept C111815664 @default.
• W3014039480 hasConcept C112672928 @default.
• W3014039480 hasConcept C11783203 @default.
• W3014039480 hasConcept C126322002 @default.
• W3014039480 hasConcept C201903717 @default.
• W3014039480 hasConcept C2778004101 @default.
• W3014039480 hasConcept C2779054382 @default.
• W3014039480 hasConcept C2779134260 @default.
• W3014039480 hasConcept C2779234561 @default.
• W3014039480 hasConcept C42407357 @default.
• W3014039480 hasConcept C44249647 @default.
• W3014039480 hasConcept C54355233 @default.
• W3014039480 hasConcept C55493867 @default.
• W3014039480 hasConcept C68443243 @default.
• W3014039480 hasConcept C71924100 @default.
• W3014039480 hasConcept C72563966 @default.
• W3014039480 hasConcept C86803240 @default.
• W3014039480 hasConceptScore W3014039480C111815664 @default.
• W3014039480 hasConceptScore W3014039480C112672928 @default.
• W3014039480 hasConceptScore W3014039480C11783203 @default.
• W3014039480 hasConceptScore W3014039480C126322002 @default.
• W3014039480 hasConceptScore W3014039480C201903717 @default.
• W3014039480 hasConceptScore W3014039480C2778004101 @default.
• W3014039480 hasConceptScore W3014039480C2779054382 @default.
• W3014039480 hasConceptScore W3014039480C2779134260 @default.
• W3014039480 hasConceptScore W3014039480C2779234561 @default.
• W3014039480 hasConceptScore W3014039480C42407357 @default.
• W3014039480 hasConceptScore W3014039480C44249647 @default.
• W3014039480 hasConceptScore W3014039480C54355233 @default.
• W3014039480 hasConceptScore W3014039480C55493867 @default.
• W3014039480 hasConceptScore W3014039480C68443243 @default.
• W3014039480 hasConceptScore W3014039480C71924100 @default.
• W3014039480 hasConceptScore W3014039480C72563966 @default.

• next