Matches in SemOpenAlex for { <https://semopenalex.org/work/W3014339710> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3014339710 endingPage "002215" @default.
- W3014339710 startingPage "ejhpharm" @default.
- W3014339710 abstract "<h3>Objective</h3> We investigated factors associated with a reduction in the quality of life and their OR of patients with chronic hepatitis C who underwent ledipasvir/sofosbuvir therapy. <h3>Methods</h3> The subjects were 141 outpatients who had undergone ledipasvir/sofosbuvir therapy under a diagnosis of genotype I chronic hepatitis C or Child-Pugh A compensated cirrhosis at Hitachi General Hospital. The patient background before ledipasvir/sofosbuvir therapy, laboratory data and the Chronic Liver Disease Questionnaire scores during ledipasvir/sofosbuvir therapy were investigated. The Chronic Liver Disease Questionnaire consists of 29 questions, and the mean value is calculated as the overall score through a 7-step assessment by patients. Using two divisions: a Chronic Liver Disease Questionnaire score of <7 (symptoms are present) and that of 7 (no symptoms), as objective variables, patients with a Chronic Liver Disease Questionnaire score of <7 were defined as having a reduced quality of life. Independent factors significantly associated with a reduction in the quality of life were extracted using logistic regression analysis. <h3>Results</h3> Based on the multivariate analysis, an alanine aminotransferase level of ≥23 U/L (OR: 4.380, 95% CI: 1.394 to 13.756) was extracted as an independent factor associated with a reduction in the quality of life (p<0.05). <h3>Conclusion</h3> An increase in the baseline level of alanine aminotransferase was found to play a role in the reduction in the quality of life of patients with chronic hepatitis C who had undergone ledipasvir/sofosbuvir therapy." @default.
- W3014339710 created "2020-04-10" @default.
- W3014339710 creator A5015554745 @default.
- W3014339710 creator A5037098930 @default.
- W3014339710 creator A5046764083 @default.
- W3014339710 creator A5052839056 @default.
- W3014339710 creator A5076128696 @default.
- W3014339710 date "2020-04-03" @default.
- W3014339710 modified "2023-09-24" @default.
- W3014339710 title "Factors associated with a reduction in the quality of life of patients with chronic hepatitis C treated by ledipasvir/sofosbuvir therapy" @default.
- W3014339710 cites W1981496642 @default.
- W3014339710 cites W1984722270 @default.
- W3014339710 cites W2092646281 @default.
- W3014339710 cites W2101598010 @default.
- W3014339710 cites W2115495766 @default.
- W3014339710 cites W2122469445 @default.
- W3014339710 cites W2135001286 @default.
- W3014339710 cites W2143468834 @default.
- W3014339710 cites W2317888030 @default.
- W3014339710 cites W2777856481 @default.
- W3014339710 cites W2795863480 @default.
- W3014339710 cites W2986704134 @default.
- W3014339710 doi "https://doi.org/10.1136/ejhpharm-2020-002215" @default.
- W3014339710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34728543" @default.
- W3014339710 hasPublicationYear "2020" @default.
- W3014339710 type Work @default.
- W3014339710 sameAs 3014339710 @default.
- W3014339710 citedByCount "0" @default.
- W3014339710 crossrefType "journal-article" @default.
- W3014339710 hasAuthorship W3014339710A5015554745 @default.
- W3014339710 hasAuthorship W3014339710A5037098930 @default.
- W3014339710 hasAuthorship W3014339710A5046764083 @default.
- W3014339710 hasAuthorship W3014339710A5052839056 @default.
- W3014339710 hasAuthorship W3014339710A5076128696 @default.
- W3014339710 hasBestOaLocation W30143397102 @default.
- W3014339710 hasConcept C126322002 @default.
- W3014339710 hasConcept C151956035 @default.
- W3014339710 hasConcept C159110408 @default.
- W3014339710 hasConcept C203014093 @default.
- W3014339710 hasConcept C2522874641 @default.
- W3014339710 hasConcept C2775999097 @default.
- W3014339710 hasConcept C2776455275 @default.
- W3014339710 hasConcept C2777075537 @default.
- W3014339710 hasConcept C2777214474 @default.
- W3014339710 hasConcept C2778390639 @default.
- W3014339710 hasConcept C2779102576 @default.
- W3014339710 hasConcept C2779951463 @default.
- W3014339710 hasConcept C2780040827 @default.
- W3014339710 hasConcept C3020491458 @default.
- W3014339710 hasConcept C71924100 @default.
- W3014339710 hasConcept C90924648 @default.
- W3014339710 hasConceptScore W3014339710C126322002 @default.
- W3014339710 hasConceptScore W3014339710C151956035 @default.
- W3014339710 hasConceptScore W3014339710C159110408 @default.
- W3014339710 hasConceptScore W3014339710C203014093 @default.
- W3014339710 hasConceptScore W3014339710C2522874641 @default.
- W3014339710 hasConceptScore W3014339710C2775999097 @default.
- W3014339710 hasConceptScore W3014339710C2776455275 @default.
- W3014339710 hasConceptScore W3014339710C2777075537 @default.
- W3014339710 hasConceptScore W3014339710C2777214474 @default.
- W3014339710 hasConceptScore W3014339710C2778390639 @default.
- W3014339710 hasConceptScore W3014339710C2779102576 @default.
- W3014339710 hasConceptScore W3014339710C2779951463 @default.
- W3014339710 hasConceptScore W3014339710C2780040827 @default.
- W3014339710 hasConceptScore W3014339710C3020491458 @default.
- W3014339710 hasConceptScore W3014339710C71924100 @default.
- W3014339710 hasConceptScore W3014339710C90924648 @default.
- W3014339710 hasLocation W30143397101 @default.
- W3014339710 hasLocation W30143397102 @default.
- W3014339710 hasLocation W30143397103 @default.
- W3014339710 hasOpenAccess W3014339710 @default.
- W3014339710 hasPrimaryLocation W30143397101 @default.
- W3014339710 hasRelatedWork W1190940090 @default.
- W3014339710 hasRelatedWork W1477057853 @default.
- W3014339710 hasRelatedWork W2379566638 @default.
- W3014339710 hasRelatedWork W2612654848 @default.
- W3014339710 hasRelatedWork W2613889000 @default.
- W3014339710 hasRelatedWork W2773649489 @default.
- W3014339710 hasRelatedWork W2793060991 @default.
- W3014339710 hasRelatedWork W2898412124 @default.
- W3014339710 hasRelatedWork W4247984509 @default.
- W3014339710 hasRelatedWork W2562781132 @default.
- W3014339710 isParatext "false" @default.
- W3014339710 isRetracted "false" @default.
- W3014339710 magId "3014339710" @default.
- W3014339710 workType "article" @default.