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- W3014378189 abstract "Purpose Diaphragm dysfunction due to phrenic nerve injury following cardiac surgery has been attributed to surgical trauma or topical hypothermia. The close proximity of the left phrenic nerve to the adjacent left ventricle makes it particularly vulnerable to insult following left ventricular assist device (LVAD) explantation during heart transplantation (HT). We aimed to evaluate the incidence of diaphragm dysfunction in patients after HT and correlate to LVAD support. Methods A review of the HT patients at our Center in 2000-2019 identified those with postoperative diaphragm dysfunction, diagnosed by chest X-ray or ultrasound during the two months following HT. Patients with diaphragm dysfunction pre-HT were excluded from the analysis. Results Of the 204 HT patients, 54 were bridged with LVAD and 150 were not (NoLVAD). In the LVAD group, there was a higher history of smoking (56 vs 35%, p=0.013), more men (89 vs 75%, p=0.047), and more re-do operations (mean/patient 1.1 vs 0.24, p Conclusion Phrenic nerve injury is a relatively common complication in HT recipients bridged with LVAD. However, the resulting diaphragm dysfunction is not associated with untoward early and late outcomes." @default.
- W3014378189 created "2020-04-10" @default.
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- W3014378189 date "2020-04-01" @default.
- W3014378189 modified "2023-10-16" @default.
- W3014378189 title "Explantation of Left Ventricular Assist Device as Bridge Therapy is Associated with Diaphragm Dysfunction after Heart Transplantation" @default.
- W3014378189 doi "https://doi.org/10.1016/j.healun.2020.01.141" @default.
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