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- W3014418260 endingPage "851" @default.
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- W3014418260 abstract "The blood–brain barrier (BBB) is one of the most complex and selective barriers in the human organism. Its role is to protect the brain and preserve the homeostasis of the central nervous system (CNS). The central elements of this physical and physiological barrier are the endothelial cells that form a monolayer of tightly joined cells covering the brain capillaries. However, as endothelial cells regulate nutrient delivery and waste product elimination, they are very sensitive to signals sent by surrounding cells and their environment. Indeed, the neuro-vascular unit (NVU) that corresponds to the assembly of extracellular matrix, pericytes, astrocytes, oligodendrocytes, microglia and neurons have the ability to influence BBB physiology. Extracellular vesicles (EVs) play a central role in terms of communication between cells. The NVU is no exception, as each cell can produce EVs that could help in the communication between cells in short or long distances. Studies have shown that EVs are able to cross the BBB from the brain to the bloodstream as well as from the blood to the CNS. Furthermore, peripheral EVs can interact with the BBB leading to changes in the barrier’s properties. This review focuses on current knowledge and potential applications regarding EVs associated with the BBB." @default.
- W3014418260 created "2020-04-10" @default.
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- W3014418260 date "2020-04-01" @default.
- W3014418260 modified "2023-10-18" @default.
- W3014418260 title "Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles" @default.
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- W3014418260 cites W1771659011 @default.
- W3014418260 cites W1832220924 @default.
- W3014418260 cites W1965522214 @default.
- W3014418260 cites W1971354690 @default.
- W3014418260 cites W1985458075 @default.
- W3014418260 cites W1995903088 @default.
- W3014418260 cites W2004017043 @default.
- W3014418260 cites W2009465113 @default.
- W3014418260 cites W2018522439 @default.
- W3014418260 cites W2025199750 @default.
- W3014418260 cites W2050497029 @default.
- W3014418260 cites W2051881287 @default.
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- W3014418260 cites W2066234893 @default.
- W3014418260 cites W2076722895 @default.
- W3014418260 cites W2077216169 @default.
- W3014418260 cites W2079966013 @default.
- W3014418260 cites W2087356761 @default.
- W3014418260 cites W2090794044 @default.
- W3014418260 cites W2091250479 @default.
- W3014418260 cites W2107325549 @default.
- W3014418260 cites W2107798346 @default.
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- W3014418260 cites W2266238367 @default.
- W3014418260 cites W2268364148 @default.
- W3014418260 cites W2287103293 @default.
- W3014418260 cites W2292758320 @default.
- W3014418260 cites W2295603197 @default.
- W3014418260 cites W2311868859 @default.
- W3014418260 cites W2337269107 @default.
- W3014418260 cites W2337879521 @default.
- W3014418260 cites W2352124481 @default.
- W3014418260 cites W2395300225 @default.
- W3014418260 cites W2399776559 @default.
- W3014418260 cites W2465939084 @default.
- W3014418260 cites W2511373877 @default.
- W3014418260 cites W2514206815 @default.
- W3014418260 cites W2537024319 @default.
- W3014418260 cites W2549374883 @default.
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- W3014418260 cites W2605627625 @default.
- W3014418260 cites W2606039495 @default.
- W3014418260 cites W2609176564 @default.
- W3014418260 cites W2619809678 @default.
- W3014418260 cites W2729896172 @default.
- W3014418260 cites W2738491178 @default.
- W3014418260 cites W2756085402 @default.
- W3014418260 cites W2757807906 @default.
- W3014418260 cites W2761598264 @default.
- W3014418260 cites W2770188847 @default.
- W3014418260 cites W2779249506 @default.
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- W3014418260 cites W2895430781 @default.
- W3014418260 cites W2900532810 @default.
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- W3014418260 doi "https://doi.org/10.3390/cells9040851" @default.
- W3014418260 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7226770" @default.
- W3014418260 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32244730" @default.
- W3014418260 hasPublicationYear "2020" @default.
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