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- W3014516571 abstract "Kinetic models of copper (Cu) metabolism have been developed for rats, sheep, dairy cows and humans. A stable isotope of Cu was required in order to perform a lengthy study of Cu metabolism because the longest-lived radioisotope of Cu, Cu, has a half-life of only 62 h. The use of a stable isotope required considerations not normally associated with a radioisotope tracer. This chapter discusses the effects of using the stable isotope tracer on the development and interpretation of the model. It is usually advantageous to be able to apply an assumption of steady state in studies of tracer kinetics. However, the metabolism of producing livestock is not usually in steady state. Growth of body tissue, growth of fetal tissue, production of milk, etc. cause dynamic changes throughout the body. The size of the tracer dose was a function of the analytical precision for the determination of Cu stable isotope ratios." @default.
- W3014516571 created "2020-04-10" @default.
- W3014516571 creator A5091595205 @default.
- W3014516571 date "2020-01-29" @default.
- W3014516571 modified "2023-09-24" @default.
- W3014516571 title "Copper metabolism in dairy cows: development of a model based on a stable isotope tracer" @default.
- W3014516571 doi "https://doi.org/10.1201/9780367811716-5" @default.
- W3014516571 hasPublicationYear "2020" @default.
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