FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3014531488> ?p ?o ?g. }

• W3014531488 endingPage "1934578X2090772" @default.
• W3014531488 startingPage "1934578X2090772" @default.
• W3014531488 abstract "We examined the antiosteoarthritis effect of a mixture of powdered pomegranate concentrate, eucommiae cortex, and achyranthis radix (5:4:1 w/w) (PEA-Mix). After the injection of monosodium iodoacetate (MIA), PEA-Mixs were orally administered. To assess pain-related behaviors, a von Frey filament test and open field test were performed. We also examined the knee thickness, maximum knee extension angle, bone mineral density (BMD), and compressive strength of the knee joint and performed a histopathologic analysis. The number of COX-2, tumor necrosis factor (TNF)-α, poly (ADP-ribose) polymerase (PARP), and 5-bromo-2′-deoxyuridine immunoreactive cells, the prostaglandin E 2 (PGE 2 ) and 5-lipoxygenase (LPO) levels, matrix metalloproteinase (MMP) activity, and mRNA levels of chondrogenesis-related genes were analyzed. PEA-Mix significantly inhibited the MIA-induced decrease in the paw-withdrawal threshold and total distance moved, and the MIA-induced increases in the maximum knee extension angle and knee thickness. Also, the MIA-induced loss of the knee joint articular surface region and decrease in the BMD were significantly suppressed by PEA-Mix. The MIA-induced increases in the 5-LPO, PGE 2 , MMP-2, MMP-9, COX-2, and TNF-α mRNA levels were reduced by PEA-Mix. PEA-Mix increased the MIA-mediated reduction in the SOX-9 and aggrecan mRNA levels. The number of PARP-positive cells was smaller in PEA-Mix-administered rats than in MIA-administered rats, while the number of 5-bromo-2′-deoxyuridine-positive cells was larger. Therefore, PEA-Mix relieved the MIA-induced pain-related behaviors, chondrocyte proliferation, and anti-inflammatory activity." @default.
• W3014531488 created "2020-04-10" @default.
• W3014531488 creator A5000419851 @default.
• W3014531488 creator A5046315131 @default.
• W3014531488 creator A5057504121 @default.
• W3014531488 creator A5062125510 @default.
• W3014531488 creator A5079304882 @default.
• W3014531488 date "2020-03-01" @default.
• W3014531488 modified "2023-09-23" @default.
• W3014531488 title "Effects of Pomegranate Concentrate Powder: Eucommiae Cortex: Achyranthis Radix 5:4:1 (w/w) Mixed Formula on Monosodium Iodoacetate-Induced Osteoarthritis in Rats" @default.
• W3014531488 cites W1973832004 @default.
• W3014531488 cites W1974528155 @default.
• W3014531488 cites W1986785675 @default.
• W3014531488 cites W1993283705 @default.
• W3014531488 cites W2001952131 @default.
• W3014531488 cites W2003642068 @default.
• W3014531488 cites W2003998378 @default.
• W3014531488 cites W2004236873 @default.
• W3014531488 cites W2006864238 @default.
• W3014531488 cites W2010404343 @default.
• W3014531488 cites W2013425466 @default.
• W3014531488 cites W2022219238 @default.
• W3014531488 cites W2026409525 @default.
• W3014531488 cites W2026522326 @default.
• W3014531488 cites W2029861410 @default.
• W3014531488 cites W2030161849 @default.
• W3014531488 cites W2038089520 @default.
• W3014531488 cites W2045400208 @default.
• W3014531488 cites W2047548115 @default.
• W3014531488 cites W2070416826 @default.
• W3014531488 cites W2071887366 @default.
• W3014531488 cites W2088858180 @default.
• W3014531488 cites W2094584843 @default.
• W3014531488 cites W2096874694 @default.
• W3014531488 cites W2099264907 @default.
• W3014531488 cites W2101709405 @default.
• W3014531488 cites W2107277218 @default.
• W3014531488 cites W2110379671 @default.
• W3014531488 cites W2114570899 @default.
• W3014531488 cites W2115601182 @default.
• W3014531488 cites W2117040516 @default.
• W3014531488 cites W2118519694 @default.
• W3014531488 cites W2118536886 @default.
• W3014531488 cites W2123897241 @default.
• W3014531488 cites W2135589358 @default.
• W3014531488 cites W2139882027 @default.
• W3014531488 cites W2141462478 @default.
• W3014531488 cites W2152096564 @default.
• W3014531488 cites W2167031471 @default.
• W3014531488 cites W2346313855 @default.
• W3014531488 cites W2740118744 @default.
• W3014531488 cites W2777589129 @default.
• W3014531488 cites W2908041074 @default.
• W3014531488 cites W2943881367 @default.
• W3014531488 cites W4254025084 @default.
• W3014531488 cites W1914755369 @default.
• W3014531488 doi "https://doi.org/10.1177/1934578x20907725" @default.
• W3014531488 hasPublicationYear "2020" @default.
• W3014531488 type Work @default.
• W3014531488 sameAs 3014531488 @default.
• W3014531488 citedByCount "2" @default.
• W3014531488 countsByYear W30145314882021 @default.
• W3014531488 countsByYear W30145314882022 @default.
• W3014531488 crossrefType "journal-article" @default.
• W3014531488 hasAuthorship W3014531488A5000419851 @default.
• W3014531488 hasAuthorship W3014531488A5046315131 @default.
• W3014531488 hasAuthorship W3014531488A5057504121 @default.
• W3014531488 hasAuthorship W3014531488A5062125510 @default.
• W3014531488 hasAuthorship W3014531488A5079304882 @default.
• W3014531488 hasBestOaLocation W30145314881 @default.
• W3014531488 hasConcept C126322002 @default.
• W3014531488 hasConcept C134018914 @default.
• W3014531488 hasConcept C142724271 @default.
• W3014531488 hasConcept C181199279 @default.
• W3014531488 hasConcept C185592680 @default.
• W3014531488 hasConcept C204787440 @default.
• W3014531488 hasConcept C2776164576 @default.
• W3014531488 hasConcept C2779689624 @default.
• W3014531488 hasConcept C55493867 @default.
• W3014531488 hasConcept C71924100 @default.
• W3014531488 hasConceptScore W3014531488C126322002 @default.
• W3014531488 hasConceptScore W3014531488C134018914 @default.
• W3014531488 hasConceptScore W3014531488C142724271 @default.
• W3014531488 hasConceptScore W3014531488C181199279 @default.
• W3014531488 hasConceptScore W3014531488C185592680 @default.
• W3014531488 hasConceptScore W3014531488C204787440 @default.
• W3014531488 hasConceptScore W3014531488C2776164576 @default.
• W3014531488 hasConceptScore W3014531488C2779689624 @default.
• W3014531488 hasConceptScore W3014531488C55493867 @default.
• W3014531488 hasConceptScore W3014531488C71924100 @default.
• W3014531488 hasFunder F4320322120 @default.
• W3014531488 hasIssue "3" @default.
• W3014531488 hasLocation W30145314881 @default.
• W3014531488 hasOpenAccess W3014531488 @default.
• W3014531488 hasPrimaryLocation W30145314881 @default.
• W3014531488 hasRelatedWork W1966504330 @default.
• W3014531488 hasRelatedWork W1974041167 @default.
• W3014531488 hasRelatedWork W1979139803 @default.

• next