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- W3014562809 abstract "Background and aims We evaluated the association of egg consumption with liver tests (LTs) and non-alcoholic fatty liver disease (NAFLD). This relationship is poorly documented. Methods The National Health and Nutrition Examination Survey (NHANES, 2005–2010) database was used. Analysis of covariance, adjusted linear and logistic regression models were used. Results Of the 14,369 participants, 46.8% were men and 45.2% had NAFLD. After correction for several variables including: age, gender, race, education, poverty to income ratio, alcohol intake, energy intake, smoking, and physical activity - fatty liver index (FLI), serum aspartate aminotransferase (AST) alanine aminotransferase (ALT) were 36.9, 25.8 (U/L) and 23.9 (U/L), respectively, in the first tertile (T1) reaching 68.7, 34.9 and 36.5, respectively, in the third tertile (T3) (p < 0.001 for all comparisons). In the model with same covariates, there was significant positive linear relationship between FLI (standard β coefficient (β): 0.196), AST (β: 0.099) and ALT (β: 0.112) with egg consumption and participants in the highest tertile (T3) of egg consumption had 11% higher chance of NAFLD compared with T1 (odds ratio: 1.11 and 95% confidence interval: 1.07–1.17). Of note, after more correction for triglycerides, hypertension and diabetes, the significant link between egg consumption and LTs and/or NAFLD attenuated and disappeared. Conclusion Our findings highlight the adverse role of egg consumption on LTs and likelihood of NAFLD. These associations seem to be attributable to cardio-metabolic risk factors. These findings require confirmation to improve our understanding of the role of egg consumption in the pathogenesis of NAFLD." @default.
- W3014562809 created "2020-04-10" @default.
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- W3014562809 date "2020-12-01" @default.
- W3014562809 modified "2023-10-03" @default.
- W3014562809 title "Adverse impact of egg consumption on fatty liver is partially explained by cardiometabolic risk factors: A population-based study" @default.
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- W3014562809 doi "https://doi.org/10.1016/j.clnu.2020.03.035" @default.
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