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- W3014575594 abstract "Research on the natural history of scrub typhus took place predominantly before the 1970s. This project developed modern techniques to revisit fundamental aspects of the epidemiology and ecology of the disease in Thailand and Laos. Three sites of high scrub typhus disease transmission were identified. Vector chiggers and small mammal hosts were collected, identified and tested for Orientia tsutsugamushi, the causative agent and mapped using GIS. The complex ecological interactions of infected and uninfected vectors and hosts with habitats and seasons were investigated. A low-input targeted enrichment sequencing method was developed and applied to a subset of positive samples. Over 18 months, 244 small mammals and ~17,000 chiggers were tested resulting in 279 O. tsutsugamushi PCR positive samples. Sixty-nine positive human samples were collected. Overall 8.6% of individual chiggers and 25.9% of chigger pools tested positive. At most sites" @default.
- W3014575594 created "2020-04-10" @default.
- W3014575594 creator A5029433093 @default.
- W3014575594 date "2019-01-01" @default.
- W3014575594 modified "2023-09-27" @default.
- W3014575594 title "The clinical epidemiology of scrub typhus in humans, chiggers and rodents" @default.
- W3014575594 hasPublicationYear "2019" @default.
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