Matches in SemOpenAlex for { <https://semopenalex.org/work/W3014602425> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3014602425 abstract "Abstract Background Axial spondyloarthritis (axSpA) frequently presents during working age and therefore impacts work participation. Biologic therapies have demonstrated a positive impact on work-related outcomes in clinical trials but real world data are limited. Therefore, we investigated the prevalence and predictors of work impairment and disability among axSpA patients attending a biologic therapy clinic. Methods This was a single-centre, cross-sectional study of patients with axSpA treated with biologic therapy. Work participation was assessed with the Work Productivity and Activity Impairment (WPAI) Questionnaire. Work outcomes (presenteeism, absenteeism, health-related job loss) were compared for gender, time since diagnosis, smoking status and disease outcome measures. Results Data were available for 165 patients (mean age 47.6 years, 75% male, 21% current smokers). Mean time since diagnosis was 15.5 years and mean duration of biologic therapy 4.7 years; 19/165 (11.5%) were on a tapered-dose regimen. Occupational data were available for 144 patients amongst whom 101 (70.1%) were either currently employed or in full time education. Of those eligible to work, 17/118 (14.4%) reported inability to work due to their axSpA. Amongst those in employment, 10.8% reported absenteeism due to axSpA in the week prior to their clinic visit (mean hours missed = 13). The mean work productivity impairment was 23%. Higher disease activity (BASDAI) and markers of global health, quality of life and pain, (BAS-G, ASQoL and spinal pain VAS) were associated with axSpA related job loss, absenteeism and presenteeism. Conclusions In this group of axSpA patients on biologic therapy (mean age 47.6 years), almost 1 in 6 (14.4%) reported axSpA related job loss. Poor work outcomes: axSpA-related work disability, absenteeism and presenteeism were associated with poorer scores for patient-reported disease outcome measures. Strategies for enhancing work productivity should be directed towards those patients at risk of poor work outcomes. More data are needed including details of the types of work that are most difficult with axSpA." @default.
- W3014602425 created "2020-04-10" @default.
- W3014602425 creator A5006225555 @default.
- W3014602425 creator A5016149716 @default.
- W3014602425 creator A5048469465 @default.
- W3014602425 creator A5079841924 @default.
- W3014602425 creator A5080267247 @default.
- W3014602425 creator A5084421334 @default.
- W3014602425 date "2020-04-06" @default.
- W3014602425 modified "2023-10-17" @default.
- W3014602425 title "Amongst patients taking biologic therapies for axial spondyloarthritis, which factors are associated with work non-participation?" @default.
- W3014602425 cites W1824831608 @default.
- W3014602425 cites W1857312731 @default.
- W3014602425 cites W1996797227 @default.
- W3014602425 cites W2040253550 @default.
- W3014602425 cites W2041594495 @default.
- W3014602425 cites W2086325363 @default.
- W3014602425 cites W2132885878 @default.
- W3014602425 cites W2139924244 @default.
- W3014602425 cites W2156605473 @default.
- W3014602425 cites W2157825261 @default.
- W3014602425 cites W2167682661 @default.
- W3014602425 cites W2313350004 @default.
- W3014602425 cites W2330918984 @default.
- W3014602425 cites W2462554540 @default.
- W3014602425 cites W2550757803 @default.
- W3014602425 cites W2624809462 @default.
- W3014602425 cites W2805456607 @default.
- W3014602425 cites W2886701099 @default.
- W3014602425 cites W2896718049 @default.
- W3014602425 cites W4206848228 @default.
- W3014602425 doi "https://doi.org/10.1186/s12891-020-03247-9" @default.
- W3014602425 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7137257" @default.
- W3014602425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32252744" @default.
- W3014602425 hasPublicationYear "2020" @default.
- W3014602425 type Work @default.
- W3014602425 sameAs 3014602425 @default.
- W3014602425 citedByCount "4" @default.
- W3014602425 countsByYear W30146024252022 @default.
- W3014602425 countsByYear W30146024252023 @default.
- W3014602425 crossrefType "journal-article" @default.
- W3014602425 hasAuthorship W3014602425A5006225555 @default.
- W3014602425 hasAuthorship W3014602425A5016149716 @default.
- W3014602425 hasAuthorship W3014602425A5048469465 @default.
- W3014602425 hasAuthorship W3014602425A5079841924 @default.
- W3014602425 hasAuthorship W3014602425A5080267247 @default.
- W3014602425 hasAuthorship W3014602425A5084421334 @default.
- W3014602425 hasBestOaLocation W30146024251 @default.
- W3014602425 hasConcept C126322002 @default.
- W3014602425 hasConcept C159110408 @default.
- W3014602425 hasConcept C162324750 @default.
- W3014602425 hasConcept C1862650 @default.
- W3014602425 hasConcept C187736073 @default.
- W3014602425 hasConcept C198451711 @default.
- W3014602425 hasConcept C27400517 @default.
- W3014602425 hasConcept C2776260265 @default.
- W3014602425 hasConcept C2776737852 @default.
- W3014602425 hasConcept C2777453003 @default.
- W3014602425 hasConcept C2779134260 @default.
- W3014602425 hasConcept C2779382274 @default.
- W3014602425 hasConcept C2779951463 @default.
- W3014602425 hasConcept C71924100 @default.
- W3014602425 hasConceptScore W3014602425C126322002 @default.
- W3014602425 hasConceptScore W3014602425C159110408 @default.
- W3014602425 hasConceptScore W3014602425C162324750 @default.
- W3014602425 hasConceptScore W3014602425C1862650 @default.
- W3014602425 hasConceptScore W3014602425C187736073 @default.
- W3014602425 hasConceptScore W3014602425C198451711 @default.
- W3014602425 hasConceptScore W3014602425C27400517 @default.
- W3014602425 hasConceptScore W3014602425C2776260265 @default.
- W3014602425 hasConceptScore W3014602425C2776737852 @default.
- W3014602425 hasConceptScore W3014602425C2777453003 @default.
- W3014602425 hasConceptScore W3014602425C2779134260 @default.
- W3014602425 hasConceptScore W3014602425C2779382274 @default.
- W3014602425 hasConceptScore W3014602425C2779951463 @default.
- W3014602425 hasConceptScore W3014602425C71924100 @default.
- W3014602425 hasIssue "1" @default.
- W3014602425 hasLocation W30146024251 @default.
- W3014602425 hasLocation W30146024252 @default.
- W3014602425 hasLocation W30146024253 @default.
- W3014602425 hasLocation W30146024254 @default.
- W3014602425 hasLocation W30146024255 @default.
- W3014602425 hasOpenAccess W3014602425 @default.
- W3014602425 hasPrimaryLocation W30146024251 @default.
- W3014602425 hasRelatedWork W1933575742 @default.
- W3014602425 hasRelatedWork W2099240226 @default.
- W3014602425 hasRelatedWork W2163021619 @default.
- W3014602425 hasRelatedWork W2242682076 @default.
- W3014602425 hasRelatedWork W2331943274 @default.
- W3014602425 hasRelatedWork W2796142344 @default.
- W3014602425 hasRelatedWork W2896718049 @default.
- W3014602425 hasRelatedWork W3014602425 @default.
- W3014602425 hasRelatedWork W3032422111 @default.
- W3014602425 hasRelatedWork W3204944663 @default.
- W3014602425 hasVolume "21" @default.
- W3014602425 isParatext "false" @default.
- W3014602425 isRetracted "false" @default.
- W3014602425 magId "3014602425" @default.
- W3014602425 workType "article" @default.