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• W3014611062 startingPage "518" @default.
• W3014611062 abstract "Long-term effects of conventional chemotherapy may be attributed to the stimulation of immunological responses. The intricate and delicate dialogue between the immune system, gut microbiota, and (immuno)chemotherapeutic approaches could have a decisive influence on patient outcome. Molecular mechanisms shared by ICD and cell-intrinsic pathogen defense responses could be harnessed to improve cancer immunogenicity. Manipulation of the gut microbiota could make an important contribution to successful therapy. The molecular mechanisms governing these elements, the interplay between them, and the concepts themselves require further elucidation, especially in the clinic. In recent years immunotherapy has provided new hope for cancer patients. However, some patients eventually relapse. Immunological responses are thought to underlie the long-term effects of conventional or targeted therapies. Whether this influence emerges from direct effects on cancer cells through immunogenic cell death (ICD) or by modulating the immune environment requires further clarification. ICD-related molecular mechanisms are also shared by cell-intrinsic defense responses that combat foreign intrusions. Indeed, we could potentially mimic and harness these processes to improve cancer immunogenicity. In addition, the microbiome is materializing as a missing factor in the cancer–immune therapy axis. The emerging idea of manipulating the gut microbiota to improve responses to anticancer therapy is becoming increasingly popular, but further clinical authentication is needed. In recent years immunotherapy has provided new hope for cancer patients. However, some patients eventually relapse. Immunological responses are thought to underlie the long-term effects of conventional or targeted therapies. Whether this influence emerges from direct effects on cancer cells through immunogenic cell death (ICD) or by modulating the immune environment requires further clarification. ICD-related molecular mechanisms are also shared by cell-intrinsic defense responses that combat foreign intrusions. Indeed, we could potentially mimic and harness these processes to improve cancer immunogenicity. In addition, the microbiome is materializing as a missing factor in the cancer–immune therapy axis. The emerging idea of manipulating the gut microbiota to improve responses to anticancer therapy is becoming increasingly popular, but further clinical authentication is needed." @default.
• W3014611062 created "2020-04-10" @default.
• W3014611062 creator A5031879006 @default.
• W3014611062 creator A5059782439 @default.
• W3014611062 creator A5078936429 @default.
• W3014611062 creator A5082373689 @default.
• W3014611062 date "2020-06-01" @default.
• W3014611062 modified "2023-10-14" @default.
• W3014611062 title "Novel Forms of Immunomodulation for Cancer Therapy" @default.
• W3014611062 cites W1481612531 @default.
• W3014611062 cites W1489012416 @default.
• W3014611062 cites W1545264161 @default.
• W3014611062 cites W1552872721 @default.
• W3014611062 cites W1573959016 @default.
• W3014611062 cites W1579469646 @default.
• W3014611062 cites W1591236327 @default.
• W3014611062 cites W1757016546 @default.
• W3014611062 cites W1907376618 @default.
• W3014611062 cites W1909092424 @default.
• W3014611062 cites W1923943509 @default.
• W3014611062 cites W1927999720 @default.
• W3014611062 cites W1964083798 @default.
• W3014611062 cites W1965130745 @default.
• W3014611062 cites W1972072031 @default.
• W3014611062 cites W1972687994 @default.
• W3014611062 cites W1973091654 @default.
• W3014611062 cites W1975410566 @default.
• W3014611062 cites W1987331911 @default.
• W3014611062 cites W1992416250 @default.
• W3014611062 cites W1993792235 @default.
• W3014611062 cites W1994993231 @default.
• W3014611062 cites W1998871454 @default.
• W3014611062 cites W1999998145 @default.
• W3014611062 cites W2000821185 @default.
• W3014611062 cites W2002225831 @default.
• W3014611062 cites W2003342633 @default.
• W3014611062 cites W2004266769 @default.
• W3014611062 cites W2008534009 @default.
• W3014611062 cites W2012743071 @default.
• W3014611062 cites W2015879727 @default.
• W3014611062 cites W2016612145 @default.
• W3014611062 cites W2022798707 @default.
• W3014611062 cites W2023374220 @default.
• W3014611062 cites W2026187026 @default.
• W3014611062 cites W2028107828 @default.
• W3014611062 cites W2033588946 @default.
• W3014611062 cites W2034751554 @default.
• W3014611062 cites W2038918212 @default.
• W3014611062 cites W2039745983 @default.
• W3014611062 cites W2039907390 @default.
• W3014611062 cites W2045122835 @default.
• W3014611062 cites W2047517931 @default.
• W3014611062 cites W2059128083 @default.
• W3014611062 cites W2067632426 @default.
• W3014611062 cites W2070805690 @default.
• W3014611062 cites W2073924079 @default.
• W3014611062 cites W2078164029 @default.
• W3014611062 cites W2078448383 @default.
• W3014611062 cites W2081796577 @default.
• W3014611062 cites W2085459501 @default.
• W3014611062 cites W2090662250 @default.
• W3014611062 cites W2093424661 @default.
• W3014611062 cites W2095472825 @default.
• W3014611062 cites W2105494088 @default.
• W3014611062 cites W2106949373 @default.
• W3014611062 cites W2119810076 @default.
• W3014611062 cites W2120426523 @default.
• W3014611062 cites W2124632458 @default.
• W3014611062 cites W2127152090 @default.
• W3014611062 cites W2130153302 @default.
• W3014611062 cites W2137049683 @default.
• W3014611062 cites W2137626178 @default.
• W3014611062 cites W2140145798 @default.
• W3014611062 cites W2142153200 @default.
• W3014611062 cites W2142541925 @default.
• W3014611062 cites W2144418568 @default.
• W3014611062 cites W2145736817 @default.
• W3014611062 cites W2146810078 @default.
• W3014611062 cites W2147810846 @default.
• W3014611062 cites W2150334056 @default.
• W3014611062 cites W2153512326 @default.
• W3014611062 cites W2153725546 @default.
• W3014611062 cites W2158360095 @default.
• W3014611062 cites W2164536401 @default.
• W3014611062 cites W2165456770 @default.
• W3014611062 cites W2169178790 @default.
• W3014611062 cites W2185075416 @default.
• W3014611062 cites W2210453860 @default.
• W3014611062 cites W2211069246 @default.
• W3014611062 cites W2229719906 @default.
• W3014611062 cites W2254632051 @default.
• W3014611062 cites W2264853310 @default.
• W3014611062 cites W2339405429 @default.
• W3014611062 cites W2340110554 @default.
• W3014611062 cites W2397189416 @default.
• W3014611062 cites W2409757753 @default.
• W3014611062 cites W2410581153 @default.
• W3014611062 cites W2536322725 @default.

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