Matches in SemOpenAlex for { <https://semopenalex.org/work/W3014957758> ?p ?o ?g. }
- W3014957758 endingPage "987" @default.
- W3014957758 startingPage "987" @default.
- W3014957758 abstract "Polycystic ovary syndrome (PCOS) is a complex disorder associated with ovarian dysfunction, infertility, menstrual irregularity, and hormonal impairments. Over the last decade, several studies have shown that some PCOS women have insulin resistance (InsR) and hyperinsulinemia, apart from being overweight or obese. Therefore, a crucial clinical aspect is that PCOS patients might develop glucose intolerance and type 2 diabetes. Insulin-sensitizing drugs have been used as first-line treatment to improve hyperinsulinemia in women with PCOS. Although reducing PCOS symptoms and signs, several used insulin-sensitizer drugs may induce side effects, which reduces compliance. D-chiro-inositol (DCI), which is a naturally occurring stereoisomer of inositol, has been classified as an insulin-sensitizer and seems to mitigate multiple InsR-related metabolic alterations in PCOS with a safe profile. However, according to a multi-targeted design, the supplementation with DCI can be synergistically integrated by combining other potential insulin-sensitizing drugs and/or nutraceuticals. The literature provides the initial support for using several unexplored nutraceutical interventions that may target relevant metabolic abnormalities associated with InsR in PCOS. With a need to promote interest in clinical research, this review aims to discuss the efficacy of DCI and the role of emerging nutraceuticals for managing InsR in PCOS." @default.
- W3014957758 created "2020-04-10" @default.
- W3014957758 creator A5011686017 @default.
- W3014957758 creator A5028547131 @default.
- W3014957758 creator A5042319501 @default.
- W3014957758 creator A5055477283 @default.
- W3014957758 creator A5088300868 @default.
- W3014957758 date "2020-04-02" @default.
- W3014957758 modified "2023-09-29" @default.
- W3014957758 title "Targeting Metabolic Consequences of Insulin Resistance in Polycystic Ovary Syndrome by D-chiro-inositol and Emerging Nutraceuticals: A Focused Review" @default.
- W3014957758 cites W1211954221 @default.
- W3014957758 cites W1515802783 @default.
- W3014957758 cites W1563119396 @default.
- W3014957758 cites W1577097214 @default.
- W3014957758 cites W1825040602 @default.
- W3014957758 cites W1901396699 @default.
- W3014957758 cites W1942344155 @default.
- W3014957758 cites W1965883464 @default.
- W3014957758 cites W1967263394 @default.
- W3014957758 cites W1972337204 @default.
- W3014957758 cites W1986962958 @default.
- W3014957758 cites W1987409831 @default.
- W3014957758 cites W1989460894 @default.
- W3014957758 cites W1989993444 @default.
- W3014957758 cites W1991367080 @default.
- W3014957758 cites W1992142051 @default.
- W3014957758 cites W2003766374 @default.
- W3014957758 cites W2004483728 @default.
- W3014957758 cites W2015252890 @default.
- W3014957758 cites W2021923144 @default.
- W3014957758 cites W2024448718 @default.
- W3014957758 cites W2041987863 @default.
- W3014957758 cites W2043480976 @default.
- W3014957758 cites W2044333038 @default.
- W3014957758 cites W2045633069 @default.
- W3014957758 cites W2052736276 @default.
- W3014957758 cites W2056059444 @default.
- W3014957758 cites W2056399290 @default.
- W3014957758 cites W2059419260 @default.
- W3014957758 cites W2059615819 @default.
- W3014957758 cites W2061584346 @default.
- W3014957758 cites W2065879241 @default.
- W3014957758 cites W2072977298 @default.
- W3014957758 cites W2073700284 @default.
- W3014957758 cites W2078266853 @default.
- W3014957758 cites W2083939351 @default.
- W3014957758 cites W2086102771 @default.
- W3014957758 cites W2095365589 @default.
- W3014957758 cites W2096126402 @default.
- W3014957758 cites W2098730466 @default.
- W3014957758 cites W2101316067 @default.
- W3014957758 cites W2108512287 @default.
- W3014957758 cites W2112553362 @default.
- W3014957758 cites W2113329249 @default.
- W3014957758 cites W2113552399 @default.
- W3014957758 cites W2117685492 @default.
- W3014957758 cites W2119239158 @default.
- W3014957758 cites W2120699795 @default.
- W3014957758 cites W2134745348 @default.
- W3014957758 cites W2136809402 @default.
- W3014957758 cites W2136847880 @default.
- W3014957758 cites W2142003876 @default.
- W3014957758 cites W2153887285 @default.
- W3014957758 cites W2154859309 @default.
- W3014957758 cites W2171067844 @default.
- W3014957758 cites W2186218348 @default.
- W3014957758 cites W2277630267 @default.
- W3014957758 cites W2335535846 @default.
- W3014957758 cites W2337149187 @default.
- W3014957758 cites W2345301926 @default.
- W3014957758 cites W2350855832 @default.
- W3014957758 cites W2394706564 @default.
- W3014957758 cites W2400650732 @default.
- W3014957758 cites W2403554778 @default.
- W3014957758 cites W2503951330 @default.
- W3014957758 cites W2514231583 @default.
- W3014957758 cites W2520838590 @default.
- W3014957758 cites W2619835212 @default.
- W3014957758 cites W2625244462 @default.
- W3014957758 cites W2625716677 @default.
- W3014957758 cites W2680582898 @default.
- W3014957758 cites W2735201781 @default.
- W3014957758 cites W2765952410 @default.
- W3014957758 cites W2771116533 @default.
- W3014957758 cites W2810832714 @default.
- W3014957758 cites W2885654368 @default.
- W3014957758 cites W2897984491 @default.
- W3014957758 cites W2901913741 @default.
- W3014957758 cites W2909353973 @default.
- W3014957758 cites W2945878060 @default.
- W3014957758 cites W2979338290 @default.
- W3014957758 cites W3001472142 @default.
- W3014957758 cites W92396552 @default.
- W3014957758 doi "https://doi.org/10.3390/jcm9040987" @default.
- W3014957758 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7230532" @default.
- W3014957758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32252239" @default.
- W3014957758 hasPublicationYear "2020" @default.
- W3014957758 type Work @default.